etodolac has been researched along with Invasiveness, Neoplasm in 4 studies
Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Etodolac did not increase the inhibitory effect of 5-FU on cell proliferation." | 1.32 | Combined treatment with selective cyclooxygenase-2 inhibitor and fluorinated pyrimidines for liver metastasis of colon cancer. ( Hirakawa, K; Matsunaga, N; Nishiguchi, Y; Nishino, H; Ohira, M; Seki, S; Tachimori, A; Yamada, N, 2004) |
| "Three different colon cancer cell lines, SW620, Lovo, HT-29 and a metastatic variant of HT-29, HT-29/Inv3, were employed to evaluate COX-2 expression and prostaglandin E(2) (PGE2) production in relation to their invasive abilities in vitro." | 1.31 | Tumor invasiveness and liver metastasis of colon cancer cells correlated with cyclooxygenase-2 (COX-2) expression and inhibited by a COX-2-selective inhibitor, etodolac. ( Chen, WS; Hsiao, M; Kou-Lin, J; Liu, JM; Wei, SJ; Yang, WK, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, WS | 2 |
| Liu, JH | 1 |
| Wei, SJ | 2 |
| Liu, JM | 2 |
| Hong, CY | 1 |
| Yang, WK | 2 |
| Matsunaga, N | 2 |
| Yamada, N | 2 |
| Hirakawa, K | 2 |
| Ohira, M | 1 |
| Tachimori, A | 1 |
| Nishiguchi, Y | 1 |
| Nishino, H | 1 |
| Seki, S | 1 |
| Hsiao, M | 1 |
| Kou-Lin, J | 1 |
4 other studies available for etodolac and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Colon cancer cells with high invasive potential are susceptible to induction of apoptosis by a selective COX-2 inhibitor.
Topics: Animals; Apoptosis; Cell Survival; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; | 2003 |
[Combined treatment with fluorinated pyrimidines and selective cyclooxygenase-2 inhibitors for liver metastasis of colon cancer].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Colonic Neoplasms; Cyclooxyg | 2003 |
Combined treatment with selective cyclooxygenase-2 inhibitor and fluorinated pyrimidines for liver metastasis of colon cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cell Line, Tumor; Cell Movem | 2004 |
Tumor invasiveness and liver metastasis of colon cancer cells correlated with cyclooxygenase-2 (COX-2) expression and inhibited by a COX-2-selective inhibitor, etodolac.
Topics: Aged; Aged, 80 and over; Cell Division; Cell Survival; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxy | 2001 |