Page last updated: 2024-10-26

etodolac and Fatty Liver

etodolac has been researched along with Fatty Liver in 1 studies

Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.

Fatty Liver: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.

Research Excerpts

ExcerptRelevanceReference
"Etodolac was administered at a low (2 mg/kg) or high (10 mg/kg) dose three times a week for 16 months starting at the age of 3 months."1.33Chemoprevention of spontaneous development of hepatocellular carcinomas in fatty liver Shionogi mice by a cyclooxygenase-2 inhibitor. ( Cheng, J; Hada, T; Hirasawa, T; Imanishi, H; Inagaki, S; Iwamoto, Y; Liu, W; Nakamura, H; Nishiguchi, S; Shimomura, S; Tsujimura, T; Yamamoto, T, 2006)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, W1
Nakamura, H1
Tsujimura, T1
Cheng, J1
Yamamoto, T2
Iwamoto, Y1
Imanishi, H1
Shimomura, S1
Hirasawa, T1
Inagaki, S1
Nishiguchi, S1
Hada, T1

Other Studies

1 other study available for etodolac and Fatty Liver

ArticleYear
Chemoprevention of spontaneous development of hepatocellular carcinomas in fatty liver Shionogi mice by a cyclooxygenase-2 inhibitor.
    Cancer science, 2006, Volume: 97, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Chemoprevention; Cyclooxygenase 2 Inhibitors; Dinoprostone; Etodol

2006