etodolac has been researched along with Experimental Mammary Neoplasms in 2 studies
Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Celecoxib (100 µM) was found to induce downregulation of COX-2 protein expression." | 1.40 | Usefulness of selective COX-2 inhibitors as therapeutic agents against canine mammary tumors. ( Asano, R; Saito, T; Tamura, D, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saito, T | 1 |
| Tamura, D | 1 |
| Asano, R | 1 |
| Sugihara, I | 1 |
| Yoshida, M | 1 |
| Shigenobu, T | 1 |
| Takagi, H | 1 |
| Maruyama, K | 1 |
| Takeuchi, N | 1 |
| Toda, M | 1 |
| Inoue, M | 1 |
| Nakada, H | 1 |
2 other studies available for etodolac and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
Usefulness of selective COX-2 inhibitors as therapeutic agents against canine mammary tumors.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Celecoxib; Cell Line, Tumor; Cell Prol | 2014 |
Different progression of tumor xenografts between mucin-producing and mucin-non-producing mammary adenocarcinoma-bearing mice.
Topics: Adenocarcinoma; Animals; Cell Growth Processes; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 | 2006 |