etodolac has been researched along with Endometrial Neoplasms in 4 studies
Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.
Endometrial Neoplasms: Tumors or cancer of ENDOMETRIUM, the mucous lining of the UTERUS. These neoplasms can be benign or malignant. Their classification and grading are based on the various cell types and the percent of undifferentiated cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "COX-2 is highly expressed in endometrial cancers, suggesting that a selective COX-2 inhibitor could be valuable for treating endometrial cancers that overexpress COX-2." | 1.37 | Effects of a selective COX-2 inhibitor in patients with uterine endometrial cancers. ( Hasegawa, K; Ishii, R; Kato, R; Oe, S; Torii, Y; Udagawa, Y, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hasegawa, K | 4 |
| Ishikawa, K | 2 |
| Kawai, S | 1 |
| Torii, Y | 2 |
| Kawamura, K | 2 |
| Kato, R | 4 |
| Tsukada, K | 1 |
| Udagawa, Y | 4 |
| Ishii, R | 1 |
| Oe, S | 1 |
| Komiyama, S | 1 |
| Kaneko, C | 1 |
| Ohashi, Y | 1 |
| Yasue, A | 1 |
| Achiwa, Y | 1 |
| Nishio, E | 1 |
1 trial available for etodolac and Endometrial Neoplasms
| Article | Year |
|---|---|
The effects of the selective cyclooxygenase-2 inhibitor on endometrial cytological findings in uterine endometrial cancer patients.
Topics: Aged; Antineoplastic Agents; Cyclooxygenase 2 Inhibitors; Endometrial Neoplasms; Endometrium; Etodol | 2012 |
3 other studies available for etodolac and Endometrial Neoplasms
| Article | Year |
|---|---|
Overcoming paclitaxel resistance in uterine endometrial cancer using a COX-2 inhibitor.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member | 2013 |
Effects of a selective COX-2 inhibitor in patients with uterine endometrial cancers.
Topics: Aged; Apoptosis; Case-Control Studies; Cell Cycle Proteins; Cyclooxygenase 2; Cyclooxygenase 2 Inhib | 2011 |
Expression of cyclooxygenase-2 in uterine endometrial cancer and anti-tumor effects of a selective COX-2 inhibitor.
Topics: Cell Cycle; Cell Cycle Proteins; Chemoprevention; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygen | 2005 |