Page last updated: 2024-10-26

etodolac and Colonic Polyps

etodolac has been researched along with Colonic Polyps in 2 studies

Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.

Colonic Polyps: Discrete tissue masses that protrude into the lumen of the COLON. These POLYPS are connected to the wall of the colon either by a stalk, pedunculus, or by a broad base.

Research Excerpts

ExcerptRelevanceReference
"On the basis of the results of our preliminary trial suggesting that aberrant crypt foci (ACF) could be eradicated by short-term administration of sulindac, in the present study, we explored the feasibility of using ACF as surrogate markers for chemoprevention of colorectal cancer."9.15Randomized double-blind trial of sulindac and etodolac to eradicate aberrant crypt foci and to prevent sporadic colorectal polyps. ( Hirayama, M; Kato, J; Kimura, T; Maeda, M; Mori, M; Nagashima, H; Nakano, Y; Niitsu, Y; Nojiri, S; Sato, Y; Sekikawa, H; Sonoda, T; Takahashi, Y; Takayama, T, 2011)
"On the basis of the results of our preliminary trial suggesting that aberrant crypt foci (ACF) could be eradicated by short-term administration of sulindac, in the present study, we explored the feasibility of using ACF as surrogate markers for chemoprevention of colorectal cancer."5.15Randomized double-blind trial of sulindac and etodolac to eradicate aberrant crypt foci and to prevent sporadic colorectal polyps. ( Hirayama, M; Kato, J; Kimura, T; Maeda, M; Mori, M; Nagashima, H; Nakano, Y; Niitsu, Y; Nojiri, S; Sato, Y; Sekikawa, H; Sonoda, T; Takahashi, Y; Takayama, T, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takayama, T1
Nagashima, H1
Maeda, M1
Nojiri, S1
Hirayama, M1
Nakano, Y1
Takahashi, Y1
Sato, Y1
Sekikawa, H1
Mori, M1
Sonoda, T1
Kimura, T1
Kato, J1
Niitsu, Y1
Kaihara, T1
Fu, KI1
Sano, Y1
Yamashita, K1
Ochiai, A1
Yoshida, S1
Fujimori, T1

Trials

1 trial available for etodolac and Colonic Polyps

ArticleYear
Randomized double-blind trial of sulindac and etodolac to eradicate aberrant crypt foci and to prevent sporadic colorectal polyps.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Jun-01, Volume: 17, Issue:11

    Topics: Aberrant Crypt Foci; Adenoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocol

2011

Other Studies

1 other study available for etodolac and Colonic Polyps

ArticleYear
Depressed-type early invasive colon cancer in a patient treated with cyclooxygenase-2 inhibitor.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:5

    Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Colonic Neoplasms; Colonic Polyps; Cyclooxy

2006