etodolac and Colitis
etodolac has been researched along with Colitis in 5 studies
Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe two patients in whom acute colitis developed during etodolac treatment." | 7.69 | Acute colitis associated with etodolac. ( Porensky, RS; Wilcox, GM, 1997) |
| "iii) Treatment with etodolac alone." | 5.35 | Inhibitory effects of the cyclooxygenase-2 inhibitor, etodolac, on colitis-associated tumorigenesis in p53-deficient mice treated with dextran sulfate sodium. ( Abe, A; Fujii, S; Fujimori, T; Fukui, H; Hiraishi, H; Ichikawa, K; Imura, J; Kono, T; Mukawa, K; Ono, Y; Sekikawa, A; Shinoda, M; Tominaga, K; Tomita, S; Yoshitake, N, 2008) |
| "We describe two patients in whom acute colitis developed during etodolac treatment." | 3.69 | Acute colitis associated with etodolac. ( Porensky, RS; Wilcox, GM, 1997) |
| "iii) Treatment with etodolac alone." | 1.35 | Inhibitory effects of the cyclooxygenase-2 inhibitor, etodolac, on colitis-associated tumorigenesis in p53-deficient mice treated with dextran sulfate sodium. ( Abe, A; Fujii, S; Fujimori, T; Fukui, H; Hiraishi, H; Ichikawa, K; Imura, J; Kono, T; Mukawa, K; Ono, Y; Sekikawa, A; Shinoda, M; Tominaga, K; Tomita, S; Yoshitake, N, 2008) |
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Inoue, T | 1 |
| Murano, M | 1 |
| Yoda, Y | 1 |
| Kuramoto, T | 1 |
| Kakimoto, K | 1 |
| Ishida, K | 1 |
| Kawakami, K | 1 |
| Abe, Y | 1 |
| Morita, E | 1 |
| Murano, N | 1 |
| Tokioka, S | 1 |
| Maemura, K | 1 |
| Umegaki, E | 1 |
| Higuchi, K | 1 |
| Campbell, NB | 1 |
| Jones, SL | 1 |
| Blikslager, AT | 1 |
| Takeda, J | 1 |
| Kitajima, K | 1 |
| Fujii, S | 2 |
| Horiuchi, H | 1 |
| Hori, H | 1 |
| Chibana, Y | 1 |
| Okuyama, T | 1 |
| Tominaga, K | 2 |
| Ichikawa, K | 2 |
| Ono, Y | 2 |
| Teramoto, T | 1 |
| Ohkura, Y | 1 |
| Imura, J | 2 |
| Shinoda, M | 2 |
| Chiba, T | 1 |
| Sakamoto, C | 1 |
| Kawamata, H | 1 |
| Fujimori, T | 2 |
| Mukawa, K | 1 |
| Yoshitake, N | 1 |
| Abe, A | 1 |
| Kono, T | 1 |
| Sekikawa, A | 1 |
| Fukui, H | 1 |
| Tomita, S | 1 |
| Hiraishi, H | 1 |
| Wilcox, GM | 1 |
| Porensky, RS | 1 |
Other Studies
5 other studies available for etodolac and Colitis
| Article | Year |
|---|---|
R-etodolac induces E-cadherin and suppresses colitis-related mouse colon tumorigenesis.
Topics: Animals; Antineoplastic Agents; Cadherins; Carcinoma; Colitis; Colonic Neoplasms; Cyclooxygenase 2; | 2010 |
The effects of cyclo-oxygenase inhibitors on bile-injured and normal equine colon.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Colitis; Colon; Cyclooxygenase 1; Cycloo | 2002 |
Inhibitory effects of etodolac, a selective COX-2 inhibitor, on the occurrence of tumors in colitis-induced tumorigenesis model in rats.
Topics: Animals; Colitis; Colonic Neoplasms; Cyclooxygenase Inhibitors; Disease Models, Animal; Etodolac; In | 2004 |
Inhibitory effects of the cyclooxygenase-2 inhibitor, etodolac, on colitis-associated tumorigenesis in p53-deficient mice treated with dextran sulfate sodium.
Topics: Animals; Cell Transformation, Neoplastic; Chemoprevention; Colitis; Colonic Neoplasms; Cyclooxygenas | 2008 |
Acute colitis associated with etodolac.
Topics: Acute Disease; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Colitis; Etodolac; Humans; | 1997 |