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etodolac and Colitis

etodolac has been researched along with Colitis in 5 studies

Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
"We describe two patients in whom acute colitis developed during etodolac treatment."7.69Acute colitis associated with etodolac. ( Porensky, RS; Wilcox, GM, 1997)
"iii) Treatment with etodolac alone."5.35Inhibitory effects of the cyclooxygenase-2 inhibitor, etodolac, on colitis-associated tumorigenesis in p53-deficient mice treated with dextran sulfate sodium. ( Abe, A; Fujii, S; Fujimori, T; Fukui, H; Hiraishi, H; Ichikawa, K; Imura, J; Kono, T; Mukawa, K; Ono, Y; Sekikawa, A; Shinoda, M; Tominaga, K; Tomita, S; Yoshitake, N, 2008)
"We describe two patients in whom acute colitis developed during etodolac treatment."3.69Acute colitis associated with etodolac. ( Porensky, RS; Wilcox, GM, 1997)
"iii) Treatment with etodolac alone."1.35Inhibitory effects of the cyclooxygenase-2 inhibitor, etodolac, on colitis-associated tumorigenesis in p53-deficient mice treated with dextran sulfate sodium. ( Abe, A; Fujii, S; Fujimori, T; Fukui, H; Hiraishi, H; Ichikawa, K; Imura, J; Kono, T; Mukawa, K; Ono, Y; Sekikawa, A; Shinoda, M; Tominaga, K; Tomita, S; Yoshitake, N, 2008)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inoue, T1
Murano, M1
Yoda, Y1
Kuramoto, T1
Kakimoto, K1
Ishida, K1
Kawakami, K1
Abe, Y1
Morita, E1
Murano, N1
Tokioka, S1
Maemura, K1
Umegaki, E1
Higuchi, K1
Campbell, NB1
Jones, SL1
Blikslager, AT1
Takeda, J1
Kitajima, K1
Fujii, S2
Horiuchi, H1
Hori, H1
Chibana, Y1
Okuyama, T1
Tominaga, K2
Ichikawa, K2
Ono, Y2
Teramoto, T1
Ohkura, Y1
Imura, J2
Shinoda, M2
Chiba, T1
Sakamoto, C1
Kawamata, H1
Fujimori, T2
Mukawa, K1
Yoshitake, N1
Abe, A1
Kono, T1
Sekikawa, A1
Fukui, H1
Tomita, S1
Hiraishi, H1
Wilcox, GM1
Porensky, RS1

Other Studies

5 other studies available for etodolac and Colitis

ArticleYear
R-etodolac induces E-cadherin and suppresses colitis-related mouse colon tumorigenesis.
    Oncology reports, 2010, Volume: 24, Issue:6

    Topics: Animals; Antineoplastic Agents; Cadherins; Carcinoma; Colitis; Colonic Neoplasms; Cyclooxygenase 2;

2010
The effects of cyclo-oxygenase inhibitors on bile-injured and normal equine colon.
    Equine veterinary journal, 2002, Volume: 34, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Colitis; Colon; Cyclooxygenase 1; Cycloo

2002
Inhibitory effects of etodolac, a selective COX-2 inhibitor, on the occurrence of tumors in colitis-induced tumorigenesis model in rats.
    Oncology reports, 2004, Volume: 11, Issue:5

    Topics: Animals; Colitis; Colonic Neoplasms; Cyclooxygenase Inhibitors; Disease Models, Animal; Etodolac; In

2004
Inhibitory effects of the cyclooxygenase-2 inhibitor, etodolac, on colitis-associated tumorigenesis in p53-deficient mice treated with dextran sulfate sodium.
    Oncology reports, 2008, Volume: 19, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; Chemoprevention; Colitis; Colonic Neoplasms; Cyclooxygenas

2008
Acute colitis associated with etodolac.
    Journal of clinical gastroenterology, 1997, Volume: 25, Issue:1

    Topics: Acute Disease; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Colitis; Etodolac; Humans;

1997