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etodolac and Cirrhosis, Liver

etodolac has been researched along with Cirrhosis, Liver in 2 studies

Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.

Research Excerpts

ExcerptRelevanceReference
"Etodolac is a chiral nonsteroidal anti-inflammatory drug (NSAID) that is marked as the racemate."2.39Etodolac clinical pharmacokinetics. ( Brocks, DR; Jamali, F, 1994)
" The mean half-life (t1/2) was 6 to 7 hours."2.38Profile of etodolac: pharmacokinetic evaluation in special populations. ( Brater, DC; Lasseter, KC, 1989)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brocks, DR1
Jamali, F1
Brater, DC1
Lasseter, KC1

Reviews

2 reviews available for etodolac and Cirrhosis, Liver

ArticleYear
Etodolac clinical pharmacokinetics.
    Clinical pharmacokinetics, 1994, Volume: 26, Issue:4

    Topics: Aging; Animals; Drug Interactions; Etodolac; Humans; Intestinal Absorption; Kidney Diseases; Liver C

1994
Profile of etodolac: pharmacokinetic evaluation in special populations.
    Clinical rheumatology, 1989, Volume: 8 Suppl 1

    Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Etodolac; Half-Life; Hum

1989