etodolac has been researched along with Chronic Kidney Failure in 3 studies
Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The mean half-life (t1/2) was 6 to 7 hours." | 2.38 | Profile of etodolac: pharmacokinetic evaluation in special populations. ( Brater, DC; Lasseter, KC, 1989) |
| "Twenty subjects (10 with normal renal function and 10 with moderate renal insufficiency) participated in an 8-day study to assess the effects of acute and chronic etodolac dosing on renal function." | 1.27 | Effect of etodolac in patients with moderate renal impairment compared with normal subjects. ( Anderson, SA; Brater, DC; Brown-Cartwright, D; Chen, A; Jacob, GB; Toto, RD, 1985) |
| " However, the baseline control collections after chronic dosing did not differ from the no-drug control periods." | 1.27 | Effects of nonsteroidal antiinflammatory drugs on renal function in patients with renal insufficiency and in cirrhotics. ( Anderson, SA; Brater, DC; Brown-Cartwright, D; Toto, RD, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brater, DC | 3 |
| Lasseter, KC | 1 |
| Anderson, SA | 2 |
| Brown-Cartwright, D | 2 |
| Toto, RD | 2 |
| Chen, A | 1 |
| Jacob, GB | 1 |
1 review available for etodolac and Chronic Kidney Failure
| Article | Year |
|---|---|
Profile of etodolac: pharmacokinetic evaluation in special populations.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Etodolac; Half-Life; Hum | 1989 |
2 other studies available for etodolac and Chronic Kidney Failure
| Article | Year |
|---|---|
Effect of etodolac in patients with moderate renal impairment compared with normal subjects.
Topics: Acetates; Adolescent; Adult; Aged; Chlorides; Creatinine; Drug Evaluation; Etodolac; Female; Humans; | 1985 |
Effects of nonsteroidal antiinflammatory drugs on renal function in patients with renal insufficiency and in cirrhotics.
Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Creatinine; Dinoprostone; Etodolac; Humans; Indom | 1986 |