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etodolac and Carcinoma, Epidermoid

etodolac has been researched along with Carcinoma, Epidermoid in 3 studies

Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.

Research Excerpts

ExcerptRelevanceReference
"The human tongue well-differentiated squamous carcinoma cell line, SCC-25, shows Fas-dependent apoptosis by treatment with carboplatin (CBDCA)."1.33Etodolac, a selective cyclo-oxygenase-2 inhibitor, enhances carboplatin-induced apoptosis of human tongue carcinoma cells by down-regulation of FAP-1 expression. ( Mishima, K; Nariai, Y; Yoshimura, Y, 2005)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yamamoto, K2
Kitayama, W2
Denda, A2
Morisaki, A2
Kuniyasu, H2
Kirita, T2
Mishima, K1
Nariai, Y1
Yoshimura, Y1
Inoue, M1

Other Studies

3 other studies available for etodolac and Carcinoma, Epidermoid

ArticleYear
Inhibitory effects of selective cyclooxygenase-2 inhibitors, nimesulide and etodolac, on the development of squamous cell dysplasias and carcinomas of the tongue in rats initiated with 4-nitroquinoline 1-oxide.
    Cancer letters, 2003, Sep-25, Volume: 199, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Animals; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cell Di

2003
Etodolac, a selective cyclo-oxygenase-2 inhibitor, enhances carboplatin-induced apoptosis of human tongue carcinoma cells by down-regulation of FAP-1 expression.
    Oral oncology, 2005, Volume: 41, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Carboplatin; Carcinoma, Squamous Cell; Carrier

2005
Suppressive effects of a selective cyclooxygenase-2 inhibitor, etodolac, on 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2004, Volume: 56, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Administration, Oral; Animals; Anticarcinogenic Agents; Carcinogens; Carci

2004