Page last updated: 2024-10-26

etodolac and Carcinoma, Anaplastic

etodolac has been researched along with Carcinoma, Anaplastic in 4 studies

Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.

Research Excerpts

ExcerptRelevanceReference
"As part of our screening program for cancer inhibitory agents effective specifically in the promotion stage of cancer development, we have evaluated the possible inhibitory effects of 36 non-steroidal anti-inflammatory drugs (NSAIDs) on the Epstein-Barr virus early antigen (EBV-EA) activation which was induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells."1.31Inhibition of epstein-barr virus early antigen activation promoted by 12-O-tetradecanoylphorbol-13-acetate by the non-steroidal anti-inflammatory drugs. ( Azuine, MA; Kapadia, GJ; Konoshima, T; Nishino, H; Takasaki, M; Takayasu, J; Tokuda, H, 2000)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inoue, T1
Murano, M1
Yoda, Y1
Kuramoto, T1
Kakimoto, K1
Ishida, K1
Kawakami, K1
Abe, Y1
Morita, E1
Murano, N1
Tokioka, S1
Maemura, K1
Umegaki, E1
Higuchi, K1
Noda, M1
Tatsumi, Y1
Tomizawa, M1
Takama, T1
Mitsufuji, S1
Sugihara, H1
Kashima, K1
Hattori, T1
Tsuneoka, N1
Tajima, Y1
Kitazato, A1
Fukuda, K1
Kitajima, T1
Kuroki, T1
Onizuka, S1
Kanematsu, T1
Kapadia, GJ1
Azuine, MA1
Takayasu, J1
Konoshima, T1
Takasaki, M1
Nishino, H1
Tokuda, H1

Other Studies

4 other studies available for etodolac and Carcinoma, Anaplastic

ArticleYear
R-etodolac induces E-cadherin and suppresses colitis-related mouse colon tumorigenesis.
    Oncology reports, 2010, Volume: 24, Issue:6

    Topics: Animals; Antineoplastic Agents; Cadherins; Carcinoma; Colitis; Colonic Neoplasms; Cyclooxygenase 2;

2010
Effects of etodolac, a selective cyclooxygenase-2 inhibitor, on the expression of E-cadherin-catenin complexes in gastrointestinal cell lines.
    Journal of gastroenterology, 2002, Volume: 37, Issue:11

    Topics: alpha Catenin; Animals; beta Catenin; Caco-2 Cells; Cadherins; Carcinoma; Cyclooxygenase 2; Cyclooxy

2002
Chemopreventative effect of a cyclooxygenase-2-specific inhibitor (etodolac) on chemically induced biliary carcinogenesis in hamsters.
    Carcinogenesis, 2005, Volume: 26, Issue:2

    Topics: Animals; Biliary Tract Neoplasms; Carcinoma; Choledochostomy; Cricetinae; Cyclooxygenase 2; Cyclooxy

2005
Inhibition of epstein-barr virus early antigen activation promoted by 12-O-tetradecanoylphorbol-13-acetate by the non-steroidal anti-inflammatory drugs.
    Cancer letters, 2000, Dec-20, Volume: 161, Issue:2

    Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Viral; Benzene; Carcinogens; Carcinoma;

2000