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etodolac and Canine Diseases

etodolac has been researched along with Canine Diseases in 9 studies

Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.

Research Excerpts

ExcerptRelevanceReference
"A total of 249 client-owned dogs with osteoarthritis were treated with firocoxib (5 mg/kg/day) or a positive control, etodolac (10-15 mg/kg/day), for 30 days."9.12Efficacy and safety of firocoxib in the management of canine osteoarthritis under field conditions. ( Alva, R; Bell, L; Brooks, KC; Case, J; Conzemius, M; Drag, M; Fleishman, C; Gordon, W; Hanson, PD; Romano, D; Schuessler, J; Shelley, B; Sifferman, R, 2006)
"To characterize features and response to treatment of keratoconjunctivitis sicca (KCS) associated with oral administration of etodolac in dogs."7.74Keratoconjunctivitis sicca associated with administration of etodolac in dogs: 211 cases (1992-2002). ( Crawford, DA; Fitzgerald, KE; Giuliano, EA; Klauss, G; Martin, SL; Moore, CP; Stuhr, CM; Tyler, JW, 2007)
"To evaluate in vivo activity of carprofen, deracoxib, and etodolac on prostanoid production in several target tissues in dogs with chronic osteoarthritis."7.73In vivo effects of carprofen, deracoxib, and etodolac on prostanoid production in blood, gastric mucosa, and synovial fluid in dogs with chronic osteoarthritis. ( Budsberg, SC; Reynolds, LR; Sessions, JK, 2005)
"A total of 249 client-owned dogs with osteoarthritis were treated with firocoxib (5 mg/kg/day) or a positive control, etodolac (10-15 mg/kg/day), for 30 days."5.12Efficacy and safety of firocoxib in the management of canine osteoarthritis under field conditions. ( Alva, R; Bell, L; Brooks, KC; Case, J; Conzemius, M; Drag, M; Fleishman, C; Gordon, W; Hanson, PD; Romano, D; Schuessler, J; Shelley, B; Sifferman, R, 2006)
"To characterize features and response to treatment of keratoconjunctivitis sicca (KCS) associated with oral administration of etodolac in dogs."3.74Keratoconjunctivitis sicca associated with administration of etodolac in dogs: 211 cases (1992-2002). ( Crawford, DA; Fitzgerald, KE; Giuliano, EA; Klauss, G; Martin, SL; Moore, CP; Stuhr, CM; Tyler, JW, 2007)
"To evaluate in vivo activity of carprofen, deracoxib, and etodolac on prostanoid production in several target tissues in dogs with chronic osteoarthritis."3.73In vivo effects of carprofen, deracoxib, and etodolac on prostanoid production in blood, gastric mucosa, and synovial fluid in dogs with chronic osteoarthritis. ( Budsberg, SC; Reynolds, LR; Sessions, JK, 2005)
"To evaluate adverse effects of long-term oral administration of carprofen, etodolac, flunixin meglumine, ketoprofen, and meloxicam in dogs."2.73Evaluation of adverse effects of long-term oral administration of carprofen, etodolac, flunixin meglumine, ketoprofen, and meloxicam in dogs. ( Basílio, AC; Brandão, CV; Luna, SP; Machado, LP; Moutinho, FQ; Steagall, PV; Takahira, RK, 2007)
" Improvement in force transmission was dosage dependent for the primary outcome measurement (vertical impulse)."2.69Efficacy of etodolac for the treatment of osteoarthritis of the hip joints in dogs. ( Budsberg, SC; Claxton, R; DeCamp, CE; Johnston, SA; Schwarz, PD, 1999)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's8 (88.89)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ness, TA1
Torres, SM1
Kramek, EA1
Blauvelt, MM1
Stiles, J1
Hampshire, VA1
Doddy, FM1
Post, LO1
Koogler, TL1
Burgess, TM1
Batten, PO1
Hudson, R1
McAdams, DR1
Brown, MA1
Sessions, JK1
Reynolds, LR1
Budsberg, SC3
Hanson, PD1
Brooks, KC1
Case, J1
Conzemius, M1
Gordon, W1
Schuessler, J1
Shelley, B1
Sifferman, R1
Drag, M1
Alva, R1
Bell, L1
Romano, D1
Fleishman, C1
Klauss, G1
Giuliano, EA1
Moore, CP1
Stuhr, CM1
Martin, SL1
Tyler, JW1
Fitzgerald, KE1
Crawford, DA1
Luna, SP1
Basílio, AC1
Steagall, PV1
Machado, LP1
Moutinho, FQ1
Takahira, RK1
Brandão, CV1
Johnston, SA1
Schwarz, PD1
DeCamp, CE1
Claxton, R1

Trials

4 trials available for etodolac and Canine Diseases

ArticleYear
Effect of dosing and sampling time on serum thyroxine, free thyroxine, and thyrotropin concentrations in dogs following multidose etodolac administration.
    Veterinary therapeutics : research in applied veterinary medicine, 2003,Winter, Volume: 4, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dog Diseases; Dogs; Drug Administration Schedule;

2003
Efficacy and safety of firocoxib in the management of canine osteoarthritis under field conditions.
    Veterinary therapeutics : research in applied veterinary medicine, 2006,Summer, Volume: 7, Issue:2

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dog Diseases; Dogs; Etodolac; Fem

2006
Evaluation of adverse effects of long-term oral administration of carprofen, etodolac, flunixin meglumine, ketoprofen, and meloxicam in dogs.
    American journal of veterinary research, 2007, Volume: 68, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Coagulation; Carbazole

2007
Efficacy of etodolac for the treatment of osteoarthritis of the hip joints in dogs.
    Journal of the American Veterinary Medical Association, 1999, Jan-15, Volume: 214, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dog Diseases; Dogs; Dos

1999

Other Studies

5 other studies available for etodolac and Canine Diseases

ArticleYear
Warning of an adverse effect of etodolac.
    Journal of the American Veterinary Medical Association, 2004, Aug-15, Volume: 225, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dog Diseases; Dogs; Etodolac; Keratoconjunctivitis

2004
Adverse drug event reports at the United States Food And Drug Administration Center for Veterinary Medicine.
    Journal of the American Veterinary Medical Association, 2004, Aug-15, Volume: 225, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Animals; Anthelmintics; Anti-Inflammatory Agents, Non-Stero

2004
In vivo effects of carprofen, deracoxib, and etodolac on prostanoid production in blood, gastric mucosa, and synovial fluid in dogs with chronic osteoarthritis.
    American journal of veterinary research, 2005, Volume: 66, Issue:5

    Topics: Animals; Carbazoles; Cyclooxygenase Inhibitors; Dinoprostone; Dog Diseases; Dogs; Drug Administratio

2005
Keratoconjunctivitis sicca associated with administration of etodolac in dogs: 211 cases (1992-2002).
    Journal of the American Veterinary Medical Association, 2007, Feb-15, Volume: 230, Issue:4

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dog Diseases; Dogs; Etodolac

2007
Long-term temporal evaluation of ground reaction forces during development of experimentally induced osteoarthritis in dogs.
    American journal of veterinary research, 2001, Volume: 62, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomechanical Phenomena; Carbazoles; Dog Diseases;

2001