etodolac has been researched along with Cancer of Endometrium in 4 studies
Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.
| Excerpt | Relevance | Reference |
|---|---|---|
| "COX-2 is highly expressed in endometrial cancers, suggesting that a selective COX-2 inhibitor could be valuable for treating endometrial cancers that overexpress COX-2." | 1.37 | Effects of a selective COX-2 inhibitor in patients with uterine endometrial cancers. ( Hasegawa, K; Ishii, R; Kato, R; Oe, S; Torii, Y; Udagawa, Y, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hasegawa, K | 4 |
| Ishikawa, K | 2 |
| Kawai, S | 1 |
| Torii, Y | 2 |
| Kawamura, K | 2 |
| Kato, R | 4 |
| Tsukada, K | 1 |
| Udagawa, Y | 4 |
| Ishii, R | 1 |
| Oe, S | 1 |
| Komiyama, S | 1 |
| Kaneko, C | 1 |
| Ohashi, Y | 1 |
| Yasue, A | 1 |
| Achiwa, Y | 1 |
| Nishio, E | 1 |
1 trial available for etodolac and Cancer of Endometrium
| Article | Year |
|---|---|
The effects of the selective cyclooxygenase-2 inhibitor on endometrial cytological findings in uterine endometrial cancer patients.
Topics: Aged; Antineoplastic Agents; Cyclooxygenase 2 Inhibitors; Endometrial Neoplasms; Endometrium; Etodol | 2012 |
3 other studies available for etodolac and Cancer of Endometrium
| Article | Year |
|---|---|
Overcoming paclitaxel resistance in uterine endometrial cancer using a COX-2 inhibitor.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member | 2013 |
Effects of a selective COX-2 inhibitor in patients with uterine endometrial cancers.
Topics: Aged; Apoptosis; Case-Control Studies; Cell Cycle Proteins; Cyclooxygenase 2; Cyclooxygenase 2 Inhib | 2011 |
Expression of cyclooxygenase-2 in uterine endometrial cancer and anti-tumor effects of a selective COX-2 inhibitor.
Topics: Cell Cycle; Cell Cycle Proteins; Chemoprevention; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygen | 2005 |