etodolac has been researched along with Bone Loss, Osteoclastic in 2 studies
Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Case studies of hindlimbs from normal, adjuvant arthritic, and etodolac-treated arthritic rats demonstrated the association of disease severity with inflammation, chondromalacia, replacement of adipose bone marrow with a fibroid marrow, osteoclastic bone resorption, synovial cysts, and pannus formation within the joints." | 3.67 | Prostaglandins in inflammatory bone pathology: mechanism and therapeutic benefit of etodolac. ( Hayward, MA; Howard, GA; Neuman, RG; Van Sickle, DC; Weichman, BM; Wood, DD, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kawaguchi, H | 1 |
| Chikazu, D | 1 |
| Nakamura, K | 1 |
| Kumegawa, M | 1 |
| Hakeda, Y | 1 |
| Hayward, MA | 1 |
| Howard, GA | 1 |
| Neuman, RG | 1 |
| Wood, DD | 1 |
| Weichman, BM | 1 |
| Van Sickle, DC | 1 |
2 other studies available for etodolac and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Direct and indirect actions of fibroblast growth factor 2 on osteoclastic bone resorption in cultures.
Topics: Acid Phosphatase; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Bo | 2000 |
Prostaglandins in inflammatory bone pathology: mechanism and therapeutic benefit of etodolac.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Bone and Bones | 1989 |