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etodolac and Bone Diseases

etodolac has been researched along with Bone Diseases in 2 studies

Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.

Bone Diseases: Diseases of BONES.

Research Excerpts

ExcerptRelevanceReference
" Case studies of hindlimbs from normal, adjuvant arthritic, and etodolac-treated arthritic rats demonstrated the association of disease severity with inflammation, chondromalacia, replacement of adipose bone marrow with a fibroid marrow, osteoclastic bone resorption, synovial cysts, and pannus formation within the joints."3.67Prostaglandins in inflammatory bone pathology: mechanism and therapeutic benefit of etodolac. ( Hayward, MA; Howard, GA; Neuman, RG; Van Sickle, DC; Weichman, BM; Wood, DD, 1989)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Feng, R1
Lentzsch, S1
Hayward, MA1
Howard, GA1
Neuman, RG1
Wood, DD1
Weichman, BM1
Van Sickle, DC1

Reviews

1 review available for etodolac and Bone Diseases

ArticleYear
Treatment of multiple myeloma with SDX-308.
    Drug news & perspectives, 2007, Volume: 20, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Bone Diseases; Drug Therapy; Etodola

2007

Other Studies

1 other study available for etodolac and Bone Diseases

ArticleYear
Prostaglandins in inflammatory bone pathology: mechanism and therapeutic benefit of etodolac.
    Agents and actions, 1989, Volume: 26, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Bone and Bones

1989