Page last updated: 2024-10-26

etodolac and B-Cell Leukemia

etodolac has been researched along with B-Cell Leukemia in 2 studies

Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.

Research Excerpts

ExcerptRelevanceReference
"R-etodolac (SDX-101) is an isoform of the non-steroidal anti-inflammatory drug, etodolac, and is currently being tested in phase II clinical trials for the treatment of refractory B-cell chronic lymphocytic leukemia (B-CLL)."7.73Cytotoxic effect of R-etodolac (SDX-101) in combination with purine analogs or monoclonal antibodies on ex vivo B-cell chronic lymphocytic leukemia cells. ( Cebula, B; Linke, A; Robak, P; Robak, T; Smolewski, P, 2006)
"R-etodolac (SDX-101) is an isoform of the non-steroidal anti-inflammatory drug, etodolac, and is currently being tested in phase II clinical trials for the treatment of refractory B-cell chronic lymphocytic leukemia (B-CLL)."3.73Cytotoxic effect of R-etodolac (SDX-101) in combination with purine analogs or monoclonal antibodies on ex vivo B-cell chronic lymphocytic leukemia cells. ( Cebula, B; Linke, A; Robak, P; Robak, T; Smolewski, P, 2006)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yasui, H1
Hideshima, T1
Anderson, KC1
Robak, P1
Linke, A1
Cebula, B1
Robak, T1
Smolewski, P1

Other Studies

2 other studies available for etodolac and B-Cell Leukemia

ArticleYear
Non-steroidal anti-inflammatory drug therapy for chronic lymphocytic leukemia.
    Leukemia & lymphoma, 2006, Volume: 47, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Anticarcinogenic Agents; Antineopla

2006
Cytotoxic effect of R-etodolac (SDX-101) in combination with purine analogs or monoclonal antibodies on ex vivo B-cell chronic lymphocytic leukemia cells.
    Leukemia & lymphoma, 2006, Volume: 47, Issue:12

    Topics: Alemtuzumab; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal

2006