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etodolac and Asthma, Bronchial

etodolac has been researched along with Asthma, Bronchial in 2 studies

Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.

Research Excerpts

ExcerptRelevanceReference
"The effect of etodolac, a potent COX-2 inhibitor, on cough response to inhaled capsaicin was examined in 17 patients with stable asthma in a randomized, placebo-controlled crossover study."9.14COX-2 inhibition attenuates cough reflex sensitivity to inhaled capsaicin in patients with asthma. ( Fujimura, M; Ishiguro, T; Ishiura, Y; Myou, S; Ohkura, N; Yamamoto, H, 2009)
"The effect of etodolac, a potent COX-2 inhibitor, on cough response to inhaled capsaicin was examined in 17 patients with stable asthma in a randomized, placebo-controlled crossover study."5.14COX-2 inhibition attenuates cough reflex sensitivity to inhaled capsaicin in patients with asthma. ( Fujimura, M; Ishiguro, T; Ishiura, Y; Myou, S; Ohkura, N; Yamamoto, H, 2009)
"Etodolac was found to have no effect on 5-lipoxygenase activity."1.29Effect of anti-inflammatory agent etodolac on antigen-induced contractions of the trachea and lung parenchyma of guinea pigs. ( Hamada, K; Inoue, K; Kimura, K; Shibata, Y; Ueda, F, 1994)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ishiura, Y1
Fujimura, M1
Yamamoto, H1
Ishiguro, T1
Ohkura, N1
Myou, S1
Inoue, K1
Hamada, K1
Ueda, F1
Shibata, Y1
Kimura, K1

Trials

1 trial available for etodolac and Asthma, Bronchial

ArticleYear
COX-2 inhibition attenuates cough reflex sensitivity to inhaled capsaicin in patients with asthma.
    Journal of investigational allergology & clinical immunology, 2009, Volume: 19, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Asthma; Capsaicin; Cough; Cross-Over Studies; Cyclooxygenase 2; Cycl

2009

Other Studies

1 other study available for etodolac and Asthma, Bronchial

ArticleYear
Effect of anti-inflammatory agent etodolac on antigen-induced contractions of the trachea and lung parenchyma of guinea pigs.
    Prostaglandins, leukotrienes, and essential fatty acids, 1994, Volume: 51, Issue:6

    Topics: Animals; Asthma; Benzoquinones; Disease Models, Animal; Etodolac; Guinea Pigs; Immunization, Passive

1994