etodolac has been researched along with Aging in 4 studies
Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of age and chronic dosing on the pharmacokinetics of the anti-inflammatory drug etodolac were evaluated in healthy young subjects, healthy elderly subjects, and elderly patients with osteoarthritis." | 3.67 | Etodolac kinetics in the elderly. ( Garg, D; Hicks, D; Kraml, M; Sanda, M; Scatina, J; Weidler, D, 1986) |
| "Etodolac is a chiral nonsteroidal anti-inflammatory drug (NSAID) that is marked as the racemate." | 2.39 | Etodolac clinical pharmacokinetics. ( Brocks, DR; Jamali, F, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Todesco, S | 1 |
| Del Ross, T | 1 |
| Marigliano, V | 1 |
| Ariani, A | 1 |
| Brocks, DR | 2 |
| Jamali, F | 2 |
| Russell, AS | 1 |
| Skeith, KJ | 1 |
| Scatina, J | 1 |
| Hicks, D | 1 |
| Kraml, M | 1 |
| Weidler, D | 1 |
| Garg, D | 1 |
| Sanda, M | 1 |
1 review available for etodolac and Aging
| Article | Year |
|---|---|
Etodolac clinical pharmacokinetics.
Topics: Aging; Animals; Drug Interactions; Etodolac; Humans; Intestinal Absorption; Kidney Diseases; Liver C | 1994 |
1 trial available for etodolac and Aging
| Article | Year |
|---|---|
Efficacy and tolerability of etodolac in aged patients affected by degenerative joint disease (osteoarthritis) in its active phase.
Topics: Administration, Oral; Affect; Aged; Aged, 80 and over; Aging; Anti-Inflammatory Agents, Non-Steroida | 1994 |
2 other studies available for etodolac and Aging
| Article | Year |
|---|---|
The stereoselective pharmacokinetics of etodolac in young and elderly subjects, and after cholecystectomy.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Bile; Cholecystectomy; Etodolac; Female | 1992 |
Etodolac kinetics in the elderly.
Topics: Absorption; Acetates; Administration, Oral; Adult; Aged; Aging; Blood Proteins; Chromatography, High | 1986 |