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etodolac and Aging

etodolac has been researched along with Aging in 4 studies

Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"The effects of age and chronic dosing on the pharmacokinetics of the anti-inflammatory drug etodolac were evaluated in healthy young subjects, healthy elderly subjects, and elderly patients with osteoarthritis."3.67Etodolac kinetics in the elderly. ( Garg, D; Hicks, D; Kraml, M; Sanda, M; Scatina, J; Weidler, D, 1986)
"Etodolac is a chiral nonsteroidal anti-inflammatory drug (NSAID) that is marked as the racemate."2.39Etodolac clinical pharmacokinetics. ( Brocks, DR; Jamali, F, 1994)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's3 (75.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Todesco, S1
Del Ross, T1
Marigliano, V1
Ariani, A1
Brocks, DR2
Jamali, F2
Russell, AS1
Skeith, KJ1
Scatina, J1
Hicks, D1
Kraml, M1
Weidler, D1
Garg, D1
Sanda, M1

Reviews

1 review available for etodolac and Aging

ArticleYear
Etodolac clinical pharmacokinetics.
    Clinical pharmacokinetics, 1994, Volume: 26, Issue:4

    Topics: Aging; Animals; Drug Interactions; Etodolac; Humans; Intestinal Absorption; Kidney Diseases; Liver C

1994

Trials

1 trial available for etodolac and Aging

ArticleYear
Efficacy and tolerability of etodolac in aged patients affected by degenerative joint disease (osteoarthritis) in its active phase.
    International journal of clinical pharmacology research, 1994, Volume: 14, Issue:1

    Topics: Administration, Oral; Affect; Aged; Aged, 80 and over; Aging; Anti-Inflammatory Agents, Non-Steroida

1994

Other Studies

2 other studies available for etodolac and Aging

ArticleYear
The stereoselective pharmacokinetics of etodolac in young and elderly subjects, and after cholecystectomy.
    Journal of clinical pharmacology, 1992, Volume: 32, Issue:11

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Bile; Cholecystectomy; Etodolac; Female

1992
Etodolac kinetics in the elderly.
    Clinical pharmacology and therapeutics, 1986, Volume: 39, Issue:5

    Topics: Absorption; Acetates; Administration, Oral; Adult; Aged; Aging; Blood Proteins; Chromatography, High

1986