etodolac has been researched along with Acute Disease in 9 studies
Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe two patients in whom acute colitis developed during etodolac treatment." | 7.69 | Acute colitis associated with etodolac. ( Porensky, RS; Wilcox, GM, 1997) |
| "Etodolac is a selective cyclo-oxygenase-2 (COX-2) inhibitor, with evidence of efficacy in osteoarthritis and rheumatoid arthritis." | 6.45 | Single dose oral etodolac for acute postoperative pain in adults. ( Derry, S; McQuay, HJ; Moore, RA; Tirunagari, SK, 2009) |
| " This results in an increase in the rate of absorption of the active compound and, consequently, in an earlier onset of analgesic action." | 6.38 | Piroxicam-beta-cyclodextrin in the treatment of acute pain of rheumatic disease. ( Franchimont, P; Reginster, JY, 1993) |
| "A double-blind, parallel group study was carried out in 61 patients suffering from acute gouty arthritis to compare the effectiveness of etodolac and naproxen in the relief of symptoms." | 5.07 | Effectiveness of etodolac ('Lodine') compared with naproxen in patients with acute gout. ( Di Giorgio, E; Maccagno, A; Romanowicz, A, 1991) |
| "We describe two patients in whom acute colitis developed during etodolac treatment." | 3.69 | Acute colitis associated with etodolac. ( Porensky, RS; Wilcox, GM, 1997) |
| "Etodolac is a new nonsteroidal anti-inflammatory drug (NSAID)." | 2.67 | Clinical response to etodolac in the management of pain. ( Mizraji, M, 1990) |
| "Etodolac is a selective cyclo-oxygenase-2 (COX-2) inhibitor, with evidence of efficacy in osteoarthritis and rheumatoid arthritis." | 2.45 | Single dose oral etodolac for acute postoperative pain in adults. ( Derry, S; McQuay, HJ; Moore, RA; Tirunagari, SK, 2009) |
| " This results in an increase in the rate of absorption of the active compound and, consequently, in an earlier onset of analgesic action." | 2.38 | Piroxicam-beta-cyclodextrin in the treatment of acute pain of rheumatic disease. ( Franchimont, P; Reginster, JY, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tirunagari, SK | 1 |
| Derry, S | 1 |
| Moore, RA | 1 |
| McQuay, HJ | 1 |
| Nakamura, Y | 1 |
| Takemoto, A | 1 |
| Muto, M | 1 |
| Reginster, JY | 1 |
| Franchimont, P | 1 |
| Wilcox, GM | 1 |
| Porensky, RS | 1 |
| Cunha, PD | 1 |
| Lord, RS | 1 |
| Johnson, ST | 1 |
| Wilker, PR | 1 |
| Aster, RH | 1 |
| Bougie, DW | 1 |
| Menke, ER | 1 |
| Jackson, CR | 1 |
| Bagby, MD | 1 |
| Tracy, TS | 1 |
| Grosso, VG | 1 |
| Mantero, MA | 1 |
| Mizraji, M | 1 |
| Maccagno, A | 1 |
| Di Giorgio, E | 1 |
| Romanowicz, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Incidence of Postoperative Pain After Using Different Types of Sealers (A Randomized Clinical Trial)[NCT05841290] | 40 participants (Anticipated) | Interventional | 2023-05-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for etodolac and Acute Disease
| Article | Year |
|---|---|
Single dose oral etodolac for acute postoperative pain in adults.
Topics: Acute Disease; Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase | 2009 |
Piroxicam-beta-cyclodextrin in the treatment of acute pain of rheumatic disease.
Topics: Acute Disease; Adult; beta-Cyclodextrins; Controlled Clinical Trials as Topic; Cyclodextrins; Diclof | 1993 |
4 trials available for etodolac and Acute Disease
| Article | Year |
|---|---|
The effectiveness of prophylactic etodolac on postendodontic pain.
Topics: Acute Disease; Administration, Oral; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammato | 2000 |
[Etodolac vs. piroxicam in subacute pathologies of the musculoskeletal apparatus. A double-open study].
Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Drug Evaluation; Drug Tolerance; Etod | 1992 |
Clinical response to etodolac in the management of pain.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Athletic Injuries; Bursitis; Diclofenac; Eto | 1990 |
Effectiveness of etodolac ('Lodine') compared with naproxen in patients with acute gout.
Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; D | 1991 |
3 other studies available for etodolac and Acute Disease
| Article | Year |
|---|---|
Acute generalized exanthematous pustulosis due to etodolac in a patient with an iliopsoas muscle abscess.
Topics: Acute Disease; Aged; Biopsy; Cyclooxygenase 2 Inhibitors; Drug Eruptions; Etodolac; Exanthema; Human | 2011 |
Acute colitis associated with etodolac.
Topics: Acute Disease; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Colitis; Etodolac; Humans; | 1997 |
Immune hemolytic anemia caused by sensitivity to a metabolite of etodolac, a nonsteroidal anti-inflammatory drug.
Topics: Acute Disease; Adult; Anemia, Hemolytic, Autoimmune; Animals; Anti-Inflammatory Agents, Non-Steroida | 2000 |