Page last updated: 2024-10-26

etizolam and Neuroleptic Malignant Syndrome

etizolam has been researched along with Neuroleptic Malignant Syndrome in 1 studies

etizolam: structure given in first source

Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)

Research Excerpts

ExcerptRelevanceReference
"A 59-year-old man, who was diagnosed as having Parkinson's disease and depression seven years ago and was on oral antiparkinsonian agents, antianxiety agents, and antidepressants, developed a high fever, disturbed consciousness, and marked muscle rigidity after discontinuation of etizolam and amitriptyline."7.71[A patient with Parkinson's disease complicated by hypothyroidism who developed malignant syndrome after discontinuation of etizolam]. ( Araki, T; Esaki, S; Furuya, H; Inoue, N; Kawajiri, M; Kira, J; Ohyagi, Y; Yamada, T, 2002)
"A 59-year-old man, who was diagnosed as having Parkinson's disease and depression seven years ago and was on oral antiparkinsonian agents, antianxiety agents, and antidepressants, developed a high fever, disturbed consciousness, and marked muscle rigidity after discontinuation of etizolam and amitriptyline."3.71[A patient with Parkinson's disease complicated by hypothyroidism who developed malignant syndrome after discontinuation of etizolam]. ( Araki, T; Esaki, S; Furuya, H; Inoue, N; Kawajiri, M; Kira, J; Ohyagi, Y; Yamada, T, 2002)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kawajiri, M1
Ohyagi, Y1
Furuya, H1
Araki, T1
Inoue, N1
Esaki, S1
Yamada, T1
Kira, J1

Other Studies

1 other study available for etizolam and Neuroleptic Malignant Syndrome

ArticleYear
[A patient with Parkinson's disease complicated by hypothyroidism who developed malignant syndrome after discontinuation of etizolam].
    Rinsho shinkeigaku = Clinical neurology, 2002, Volume: 42, Issue:2

    Topics: Antidepressive Agents; Depression; Diazepam; Humans; Hypothyroidism; Male; Middle Aged; Neuroleptic

2002