etiocholanolone has been researched along with Porphyrias in 9 studies
Etiocholanolone: The 5-beta-reduced isomer of ANDROSTERONE. Etiocholanolone is a major metabolite of TESTOSTERONE and ANDROSTENEDIONE in many mammalian species including humans. It is excreted in the URINE.
3alpha-hydroxy-5beta-androstan-17-one : An androstanoid that is 5beta-androstane substituted by an alpha-hydroxy group at position 3 and an oxo group at position 17. It is a metabolite of testosterone in mammals.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adult female rats were fed with a diet containing hexachlorobenzene to induce a porphyria." | 7.66 | Further evidence for the participation of 5 beta-steroids in the development of a porphyria induced by hexachlorobenzene. ( Golf, SW; Graef, V; Tyrell, C, 1982) |
| "Adult female rats were fed with a diet containing hexachlorobenzene to induce a porphyria." | 3.66 | Further evidence for the participation of 5 beta-steroids in the development of a porphyria induced by hexachlorobenzene. ( Golf, SW; Graef, V; Tyrell, C, 1982) |
| "Acute intermittent porphyria is a gentic disease associated with changes in the activity of some of the hepatic enzymes in the heme biosynthetic pathway and in the activity of delta4-5alpha-steroid reductase, an enzyme involved in steroid metabolism." | 1.25 | Cytoplasmic receptor protein for etiochalanolone in chick embryo liver. ( Gidari, AS; Lane, SE; Levere, RD, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kappas, A | 2 |
| Granick, S | 1 |
| Graef, V | 1 |
| Golf, SW | 1 |
| Tyrell, C | 1 |
| Lane, SE | 1 |
| Gidari, AS | 1 |
| Levere, RD | 1 |
| Paxton, JW | 2 |
| Moore, MR | 3 |
| Beattie, AD | 2 |
| Goldberg, A | 3 |
| Hall, PE | 1 |
| McCallum, J | 1 |
| Grant, JK | 1 |
| Bradlow, HL | 1 |
| Gillette, PN | 1 |
| Gallagher, TF | 1 |
| Pinelli, A | 1 |
| Pozzo, G | 1 |
| Formento, ML | 1 |
| Deattie, AD | 1 |
| Shanley, BC | 1 |
| Zail, SS | 1 |
| Joubert, SM | 1 |
9 other studies available for etiocholanolone and Porphyrias
| Article | Year |
|---|---|
Steroid induction of porphyrin synthesis in liver cell culture.
Topics: Culture Techniques; Etiocholanolone; Glucocorticoids; Heme; Humans; Liver; Porphyrias; Porphyrins | 1967 |
Further evidence for the participation of 5 beta-steroids in the development of a porphyria induced by hexachlorobenzene.
Topics: Animals; Chlorobenzenes; Etiocholanolone; Female; Flutamide; Hexachlorobenzene; Liver; Oxidoreductas | 1982 |
Cytoplasmic receptor protein for etiochalanolone in chick embryo liver.
Topics: Animals; Binding Sites; Binding, Competitive; Chick Embryo; Chloromercuribenzoates; Cytosol; Ethylma | 1975 |
Urinary excretion of 17-oxosteroids in hereditary coproporphyria.
Topics: 17-Ketosteroids; Adult; Aminolevulinic Acid; Androsterone; Coproporphyrins; Etiocholanolone; Female; | 1975 |
Excessive urinary excretion of certain porphyrinogenic steroids in human acute intermittent porphyria.
Topics: Acute Disease; Adult; Androsterone; Animals; Chromatography, Gas; Chromatography, Thin Layer; Dehydr | 1969 |
Studies in porphyria. I. A defect in the reductive transformation of natural steroid hormones in the hereditary liver disease, acute intermittent porphyria.
Topics: 5-Aminolevulinate Synthetase; Adult; Androsterone; Carbon Isotopes; Dehydroepiandrosterone; Enzyme I | 1972 |
[Study of urinary steroids in 2 cases of porphyria cutanea tarda. Effects of the administration of vitamin E in large doses].
Topics: Androsterone; Dehydroepiandrosterone; Etiocholanolone; Humans; Porphyrias; Pregnanediol; Vitamin E | 1970 |
17-Oxosteroid conjugates in plasma and urine of patients with acute intermittent porphyria.
Topics: 17-Ketosteroids; 5-Aminolevulinate Synthetase; Adult; Androgens; Androsterone; Animals; Chromatograp | 1974 |
Aetiocholanolone conjugation in symptomatic porphyria.
Topics: Adult; Ethanol; Etiocholanolone; Female; Humans; Liver Diseases; Male; Middle Aged; Porphyrias; Porp | 1970 |