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etiocholanolone and Polycystic Ovary Syndrome

etiocholanolone has been researched along with Polycystic Ovary Syndrome in 19 studies

Etiocholanolone: The 5-beta-reduced isomer of ANDROSTERONE. Etiocholanolone is a major metabolite of TESTOSTERONE and ANDROSTENEDIONE in many mammalian species including humans. It is excreted in the URINE.
3alpha-hydroxy-5beta-androstan-17-one : An androstanoid that is 5beta-androstane substituted by an alpha-hydroxy group at position 3 and an oxo group at position 17. It is a metabolite of testosterone in mammals.

Polycystic Ovary Syndrome: A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading.

Research Excerpts

ExcerptRelevanceReference
"Insulin sensitivity, GH, adiponectin, and IGF-I significantly increased during pioglitazone treatment, whereas alloTHF/THF levels significantly decreased."9.14A randomized placebo-controlled study on the effects of pioglitazone on cortisol metabolism in polycystic ovary syndrome. ( Andersen, M; Bennett, P; Flyvbjerg, A; Frystyk, J; Glintborg, D; Hagen, C; Hermann, AP; Jensen, LT, 2009)
"Insulin sensitivity, GH, adiponectin, and IGF-I significantly increased during pioglitazone treatment, whereas alloTHF/THF levels significantly decreased."5.14A randomized placebo-controlled study on the effects of pioglitazone on cortisol metabolism in polycystic ovary syndrome. ( Andersen, M; Bennett, P; Flyvbjerg, A; Frystyk, J; Glintborg, D; Hagen, C; Hermann, AP; Jensen, LT, 2009)
" Dose-response studies revealed that the concentration of 5 alpha-androstane-3, 17-dione present in FF form normal dominant follicles (79."1.29A mechanism for the suppression of estrogen production in polycystic ovary syndrome. ( Agarwal, SK; Judd, HL; Magoffin, DA, 1996)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199014 (73.68)18.7374
1990's3 (15.79)18.2507
2000's2 (10.53)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KLEINFELDER, H1
HUSMAN, F1
ZAMPI, G1
BORGHI, A1
TOCCAFONDI, R1
GIUSTI, G1
Glintborg, D1
Hermann, AP1
Hagen, C1
Jensen, LT1
Frystyk, J1
Bennett, P1
Flyvbjerg, A1
Andersen, M1
Agarwal, SK1
Judd, HL1
Magoffin, DA1
Szilágyi, A1
Homoki, J1
Bellyei, S1
Szabó, I1
Vejlsted, H1
Albrechtsen, R1
Stewart, PM1
Shackleton, CH1
Beastall, GH1
Edwards, CR1
Mauvais-Jarvis, P2
Rivera, R1
Dorfman, RI1
Forchielli, E1
Stárka, L1
Sulcová, J1
Solomon, D1
Strummer, D1
Nair, PP1
Garmendia, F1
Nicolis, GL1
Gabrilove, JL1
Bird, CE1
Clark, AF1
Hofmann, P1
König, A1
Haller, J1
Yamada, S1
Hoek, W1
van Kampen, EJ1
Lawrence, DM1
Bercovici, JP1
Floch, HH1

Reviews

1 review available for etiocholanolone and Polycystic Ovary Syndrome

ArticleYear
[CLINICAL AND ANATOMO-HISTOLOGICAL STUDY OF 21 CASES OF HIRSUTISM WITH MENSTRUAL DISORDERS AND POLYCYSTIC OVARY, WITH REFERENCE TO THE PROBLEMS OF OVARIAN ORIGIN OF HIRSUTISM AND OF THE SO-CALLED STEIN-LEVENTHAL SYNDROME].
    Archivio "de Vecchi" per l'anatomia patologica e la medicina clinica, 1963, Volume: 40

    Topics: 17-Ketosteroids; Adolescent; Amenorrhea; Androsterone; Cysts; Etiocholanolone; Female; Hirsutism; Hu

1963

Trials

2 trials available for etiocholanolone and Polycystic Ovary Syndrome

ArticleYear
A randomized placebo-controlled study on the effects of pioglitazone on cortisol metabolism in polycystic ovary syndrome.
    Fertility and sterility, 2009, Volume: 91, Issue:3

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adiponectin; Androsterone; Blood Glucose; Denmark; Etiocholan

2009
Hormonal and clinical effects of chronic gonadotropin-releasing hormone agonist treatment in polycystic ovary syndrome.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2000, Volume: 14, Issue:5

    Topics: Adult; Androsterone; Drug Implants; Estradiol; Etiocholanolone; Female; Follicle Stimulating Hormone

2000

Other Studies

16 other studies available for etiocholanolone and Polycystic Ovary Syndrome

ArticleYear
[THE EXCRETION OF ADRENAL CORTEX STEROIDS IN PATIENTS WITH HIRSUTISM AFTER ORAL ADMINISTRATION OF METOPIRON].
    Klinische Wochenschrift, 1963, Dec-01, Volume: 41

    Topics: 17-Ketosteroids; Administration, Oral; Adrenal Cortex; Adrenal Cortex Hormones; Androsterone; Etioch

1963
A mechanism for the suppression of estrogen production in polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:10

    Topics: Adolescent; Adult; Androstenedione; Aromatase; Aromatase Inhibitors; Cells, Cultured; Enzyme Inhibit

1996
Biochemical and Clinical Effect of Ovarian Wedge Resection in the Polycystic Ovary Syndrome.
    Obstetrics and gynecology, 1976, Volume: 47, Issue:5

    Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Function Tests; Adult; Androgens; Androsterone; Dehydroe

1976
5 alpha-reductase activity in polycystic ovary syndrome.
    Lancet (London, England), 1990, Feb-24, Volume: 335, Issue:8687

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adrenocorticotropic Hormone; Adult; Androstenedione; Androste

1990
5 alpha-reductase and polycystic ovaries.
    Lancet (London, England), 1990, May-26, Volume: 335, Issue:8700

    Topics: Androsterone; Cholestenone 5 alpha-Reductase; Etiocholanolone; Female; Humans; Oxidoreductases; Poly

1990
[In vivo studies on metabolism of androgens following administration of steroidal inhibitors of ovulation. II. Metabolism of radioactive testosterone and dehydroepiandrosterone sulfate in subjects treated with lynestrenol, synthetic estrogens and their co
    Acta endocrinologica, 1966, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Androsterone; Chromatography, Paper; Dehydroepiandrosterone; Ethinyl Estradiol; E

1966
A modified method for the analysis of urinary 17-ketosteroids, pregnanediol and pregnanetriol by gas liquid chromatography in normal subjects and subjects with various endocrine disorders.
    Acta endocrinologica, 1967, Volume: 54, Issue:1

    Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Androsterone; Chromatography, Gas; Cushing Syndrom

1967
[Influence of dehydroepiandrosterone on the secretion of corticoids].
    Endokrinologie, 1964, Volume: 46, Issue:5

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adult; Androsterone; Cholesterol; Circadia

1964
Routine assay of 11-deoxy-17-ketosteroids in human urinary gas-liquid chromatography with a standardized column.
    American journal of clinical pathology, 1967, Volume: 48, Issue:3

    Topics: 17-Ketosteroids; Adrenal Gland Diseases; Androsterone; Chromatography, Gas; Dehydroepiandrosterone;

1967
The determination of urinary pregnanetriol and the neutral 17-ketosteroids by gas-liquid chromatography.
    Steroids, 1971, Volume: 18, Issue:2

    Topics: 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adre

1971
A single method for determination of urine steroids. I. Levels of testosterone, epitestosterone and 17-ketosteroid fractions. II. Specific activities of testosterone, androsterone and etiocholanolone and production rate of testosterone following administr
    Clinical biochemistry, 1970, Volume: 3, Issue:3

    Topics: 17-Ketosteroids; Adolescent; Adult; Aged; Androsterone; Breast Neoplasms; Carbon Isotopes; Carcinoma

1970
[Arrhenoblastoma].
    Zentralblatt fur Gynakologie, 1972, May-27, Volume: 94, Issue:21

    Topics: 17-Ketosteroids; Adenoma; Adrenal Cortex Hormones; Adult; Androsterone; Chromatography; Diagnosis, D

1972
[Clinical studies on the secretion and metabolism of testosterone using radioactive testosterone. II. Studies in the patients with various endocrine disorders and hepatic diseases].
    Naika hokan. Japanese archives of internal medicine, 1971, Volume: 18, Issue:4

    Topics: Addison Disease; Adolescent; Adrenal Insufficiency; Adrenocortical Hyperfunction; Adult; Androsteron

1971
Urinary steroid spectra by gas chromatography.
    Clinica chimica acta; international journal of clinical chemistry, 1968, Volume: 19, Issue:3

    Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adult; Breast Neoplasms; Child; Chromatography, Ga

1968
Steroid excretion in the Stein-Leventhal syndrome.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1968, Volume: 75, Issue:9

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adult; Androsterone; Estradiol; Estriol; Estrogens; Estron

1968
[Influence of sex hormones on the metabolism of androgens].
    Revue francaise d'etudes cliniques et biologiques, 1969, Volume: 14, Issue:2

    Topics: Adult; Androgens; Androstanes; Androsterone; Carbon Isotopes; Child; Chorionic Gonadotropin; Enzyme

1969