Page last updated: 2024-11-07

etiocholanolone and Neoplasms

etiocholanolone has been researched along with Neoplasms in 19 studies

Etiocholanolone: The 5-beta-reduced isomer of ANDROSTERONE. Etiocholanolone is a major metabolite of TESTOSTERONE and ANDROSTENEDIONE in many mammalian species including humans. It is excreted in the URINE.
3alpha-hydroxy-5beta-androstan-17-one : An androstanoid that is 5beta-androstane substituted by an alpha-hydroxy group at position 3 and an oxo group at position 17. It is a metabolite of testosterone in mammals.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
" In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome."4.80Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000)
"Dehydroepiandrosterone (DHEA) is a naturally occurring steroid synthesized in the adrenal cortex, gonads, brain, and gastrointestinal tract, and it is known to have chemopreventive and anti-proliferative actions on tumors."1.32Anti-proliferative action of endogenous dehydroepiandrosterone metabolites on human cancer cell lines. ( Fujimoto, Y; Fukushima, S; Honda, A; Matsuzaki, Y; Miyazaki, H; Salen, G; Takagiwa, A; Tanaka, N; Yoshida, S, 2003)
"In patients with breast and prostate cancer hormone excretion patterns differ in a similar way from patterns in persons without cancer."1.24HORMONE EXCRETION PATTERNS IN BREAST AND PROSTATE CANCER ARE ABNORMAL. ( HOPKINS, CE; MARMORSTON, J; STERN, E; WEINER, JM, 1964)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199017 (89.47)18.7374
1990's0 (0.00)18.2507
2000's2 (10.53)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tukey, RH1
Strassburg, CP1
Yoshida, S1
Honda, A1
Matsuzaki, Y1
Fukushima, S1
Tanaka, N1
Takagiwa, A1
Fujimoto, Y1
Miyazaki, H1
Salen, G1
PESONEN, S1
MIKKONEN, R1
HELLMAN, L1
ZUMOFF, B1
COHN, ML1
SAKAMOTO, A1
FRANCIS, KC1
CLARK, DG1
FUKUSHIMA, DK1
GALLAGHER, TF1
TRETBAR, HA1
CAWLEY, LP1
NILSSON, SE1
ARPELS, C1
BABCOCK, VI1
SOUTHAM, CM1
BENARD, H1
BOURDIN, JS1
TAGLIANTESARACINO, R1
SEEMAN, A1
STERN, E1
HOPKINS, CE1
WEINER, JM1
MARMORSTON, J1
WEST, CD1
KUMAGAI, LF1
SIMONS, EL1
DOMINGUEZ, OB1
BERLINER, DL1
SCHUBERT, K1
BACIGALUPO, G1
Vogel, JM2
Yankee, RA1
Kimball, HR2
Wolff, SM2
Perry, S2
Brubaker, LH1
Johnson, CA1
Barnes, A1
Rosenstein, DL1
Hewett, JE1
Garnham, JR1
Bulbrook, RD1
Wang, DY1
Karjalainen, J1
Wasastjerna, C1
Bodansky, O1
Gino, GC1
Bumma, C1
Calciati, A1
La Grotta, G1
Sala, A1

Reviews

1 review available for etiocholanolone and Neoplasms

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia;

2000

Other Studies

18 other studies available for etiocholanolone and Neoplasms

ArticleYear
Anti-proliferative action of endogenous dehydroepiandrosterone metabolites on human cancer cell lines.
    Steroids, 2003, Volume: 68, Issue:1

    Topics: Cell Division; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, D

2003
Observations on the significance of dehydroepiandrosterone, androsterone and etiocholanolone determinations in the differential diagnosis of certain adrenal and ovarian diseases.
    Acta endocrinologica, 1958, Volume: 27, Issue:2

    Topics: Adrenal Cortex; Adrenal Cortex Diseases; Androgens; Androsterone; Dehydroepiandrosterone; Diagnosis,

1958
An anti-tumor property of etiocholanolone in man.
    Transactions of the Association of American Physicians, 1962, Volume: 75

    Topics: Anatomy; Antineoplastic Agents; Etiocholanolone; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large

1962
CUSHING'S SYNDROME.
    The Journal of the Kansas Medical Society, 1963, Volume: 64

    Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Androgens; Androsterone; Carcinoma; Carcinoma, Broncho

1963
[PERIODICALLY APPEARING DISEASE SYMPTOMS].
    Svenska lakartidningen, 1963, Dec-04, Volume: 60

    Topics: 17-Ketosteroids; Agranulocytosis; Communicable Diseases; Edema; Endocrinology; Etiocholanolone; Fami

1963
EFFECT OF STEROIDS ON HUMAN CELL CULTURES; SUSTAINING EFFECT OF HYDROCORTISONE.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 115

    Topics: 17-Ketosteroids; Androsterone; Dehydroepiandrosterone; Estradiol; Etiocholanolone; Hydrocortisone; H

1964
[INFLUENCE OF TESTOSTERONE ADMINISTRATION ON PLASMA 17-KETOSTEROID LEVELS].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1964, Jan-06, Volume: 258

    Topics: 17-Ketosteroids; Androsterone; Etiocholanolone; Neoplasms; Pharmacology; Plasma; Testosterone

1964
HORMONE EXCRETION PATTERNS IN BREAST AND PROSTATE CANCER ARE ABNORMAL.
    Science (New York, N.Y.), 1964, Aug-14, Volume: 145, Issue:3633

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Aged; Androsterone; Breast Neoplasms; Creatine; Creatinine

1964
ADRENOCORTICAL CARCINOMA WITH FEMINIZATION AND HYPERTENSION ASSOCIATED WITH A DEFECT IN 11-BETA-HYDROXYLATION.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acne Vulgaris; Adrenal Cortex Hormones; Adrenal Gland Ne

1964
DIFFERENCES OF STEROID METABOLISM IN BREAST CANCER AFTER HORMONE STIMULATION.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Androgens; Androsterone; Breast Diseases; Breast Neoplasms

1964
The effect of etiocholanolone on granulocyte kinetics.
    Blood, 1967, Volume: 30, Issue:4

    Topics: Bone Marrow; Bone Marrow Cells; Etiocholanolone; Female; Humans; In Vitro Techniques; Isoflurophate;

1967
A new test for both neutrophil marrow reserves and intravascular survival.
    The Journal of laboratory and clinical medicine, 1976, Volume: 87, Issue:6

    Topics: Adult; Aged; Bone Marrow; Bone Marrow Cells; Cell Survival; Etiocholanolone; Female; Hematopoiesis;

1976
Hormone profiles and discriminant functions in cancer.
    Lancet (London, England), 1970, Nov-21, Volume: 2, Issue:7682

    Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Breast Neoplasms; Etiocholanolone; Female; Human

1970
Conjugated and unconjugated dehydroepiandrosterone, aetiocholanolone and androsterone in the peripheral plasma of patients with cancer of the breast, ovary, uterus or prostate.
    European journal of cancer, 1969, Volume: 5, Issue:3

    Topics: Adult; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Male

1969
The etiocholanolone test for prediction of the leukopenic effect of cytoxic drugs.
    Scandinavian journal of haematology, 1973, Volume: 11, Issue:5

    Topics: Adult; Antineoplastic Agents; Cell Survival; Cyclophosphamide; Depression, Chemical; Etiocholanolone

1973
Reflections on biochemical aspects of human cancer. The Lucy Wortham James Lecture.
    Cancer, 1974, Volume: 33, Issue:2

    Topics: Alkaline Phosphatase; Blood Proteins; Breast Neoplasms; Carcinoembryonic Antigen; Colonic Neoplasms;

1974
Etiocholanolone in the evaluation of marrow reserves in patients receiving cytotoxic agents.
    Annals of internal medicine, 1967, Volume: 67, Issue:6

    Topics: Adult; Antineoplastic Agents; Bone Marrow Examination; Burkitt Lymphoma; Child; Choriocarcinoma; End

1967
[Etiocholanolone in the evaluation of bone marrow reserve in patients treated with bone marrow depressants].
    Il Cancro, 1971, Volume: 24, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Bone Marrow; Etiocholanolone; Humans; Leukopenia; Male; Middle A

1971