Page last updated: 2024-11-07

etiocholanolone and Hypergonadotropic Hypogonadism

etiocholanolone has been researched along with Hypergonadotropic Hypogonadism in 19 studies

Etiocholanolone: The 5-beta-reduced isomer of ANDROSTERONE. Etiocholanolone is a major metabolite of TESTOSTERONE and ANDROSTENEDIONE in many mammalian species including humans. It is excreted in the URINE.
3alpha-hydroxy-5beta-androstan-17-one : An androstanoid that is 5beta-androstane substituted by an alpha-hydroxy group at position 3 and an oxo group at position 17. It is a metabolite of testosterone in mammals.

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199019 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SCHOEN, EJ1
DENEVE, L1
VERMEULEN, A1
Christiansen, P1
Metcalf, MG2
Cowles, RJ1
Skre, H1
Bassöe, HH1
Berg, K1
Frövig, AG1
Landyshev, IuS1
Mishuk, VP1
Schmidt, H1
Starcevic, Z1
Teller, WM1
Krese, A1
Teller, W1
Horký, K2
Küchel, O2
Gregorvá, I1
Stárka, L2
Zimprich, H1
Gregorová, I1
Scurry, MT1
Bruton, J1
Barry, KG1
Crook, D1
Jeffcoate, SL1
Brooks, RV1
Lim, NY1
London, DR1
Prunty, FT1
Spathis, GS1
Takahara, J1
Hashimoto, K1
Ofuji, T1
Vogt, JH1
Norman, N1
Aakvaag, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Aromatase Inhibition and Testosterone Replacement in Sex Steroids, Pituitary Hormones, Markers of Bone Turnover, Muscle Strength, and Cognition in Older Men[NCT00104572]Phase 244 participants (Actual)Interventional2004-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Effect of Testosterone Gel vs. Anastrozole on Bone Mineral Density

bone mineral density lumbar spine for all arms testosterone gel, anastrozole and placebo (NCT00104572)
Timeframe: 1 year

Interventiong/cm2 (Mean)
Transdermal Testosterone0.042
Aromatase Inhibitor0.008
Placebo0.047

Effect of Testosterone Gel vs. Anastrozole on Glucose Tolerance/Lipid Metabolism

"Primary outcome HOMA-IR for all groups testosterone gel, anastrozole and placebo Insulin resistance measure by HOMA-IR is a score if a person is insulin resistance the score should be between minimum 0.7- maximum 2 or more.~Absolute changes in HOMAIR in all treatment arms, calculation time frame 1 year minus baseline point." (NCT00104572)
Timeframe: 1 year

Interventionscore on a scale (Mean)
Transdermal Testosterone-0.05
Aromatase Inhibitor0.15
Placebo-0.11

Effect of Testosterone Gel vs. Anastrozole on Prostate Volume/Prostate Specific Antigen Levels/Urinary Function

"rectal ultrasound prostate volume for all groups testosterone gel, anastrozole and placebo.~Absolute changes in prostate volume in all treatment arms, calculation time frame 1 year minus baseline point." (NCT00104572)
Timeframe: 1 year

Interventioncc (Mean)
Transdermal Testosterone4.5
Aromatase Inhibitor-1.66
Placebo-1.05

Effect of Testosterone Gel vs. Anastrozole on Pulsatile Growth Hormone Release

Overnight Growth hormone measures (total hormone secretion) for groups testosterone gel, anastrozole and placebo (NCT00104572)
Timeframe: 1 year

Interventionng/ml/8h (Mean)
Transdermal Testosterone5.8
Aromatase Inhibitor10
Placebo7.7

Trials

1 trial available for etiocholanolone and Hypergonadotropic Hypogonadism

ArticleYear
Qualitative alterations in urinary 17-ketosteroid excretion during aminoglutethimide administration.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:2

    Topics: 17-Ketosteroids; Adrenocortical Hyperfunction; Aminoglutethimide; Androsterone; Aniline Compounds; A

1969

Other Studies

18 other studies available for etiocholanolone and Hypergonadotropic Hypogonadism

ArticleYear
DIMINISHED TESTICULAR FUNCTION IN "MALE TURNER'S SYNDROME".
    The Journal of clinical endocrinology and metabolism, 1965, Volume: 25

    Topics: 17-Ketosteroids; Adolescent; Androsterone; Chorionic Gonadotropin; Chromosome Aberrations; Chromosom

1965
THE DETERMINATION OF 17-OXOSTEROID SULPHATES IN HUMAN PLASMA.
    The Journal of endocrinology, 1965, Volume: 32

    Topics: 17-Ketosteroids; Addison Disease; Adolescent; Adrenalectomy; Androsterone; Blood Chemical Analysis;

1965
Urinary gonadotrophins in the Sertoli-Cell-only syndrome.
    Acta endocrinologica, 1975, Volume: 78, Issue:1

    Topics: Adult; Androgens; Androsterone; Biological Assay; Biopsy; Castration; Dehydroepiandrosterone; Dexame

1975
Response of plasma testosterone, urinary 17-oxosteroids, oestrogens, and androsterone plus aetiocholanolone to human chorionic gonadotrophin in dexamethasone-suppressed men.
    Clinical endocrinology, 1976, Volume: 5, Issue:3

    Topics: 17-Ketosteroids; Adolescent; Adrenal Glands; Adult; Androsterone; Chorionic Gonadotropin; Depression

1976
Cerebellar ataxia and hypergonadotropic hypogonadism in two kindreds. Chance concurrence, pleiotropism or linkage?
    Clinical genetics, 1976, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Androstenols; Cerebellar Ataxia; Estrenes; Etiocholanolone; Female; Genetic Linka

1976
[Functional status of the hypophyseal-gonadal system in patients with chronic bronchitis].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:4

    Topics: 17-Ketosteroids; Adult; Androsterone; Bronchitis; Chronic Disease; Etiocholanolone; Follicle Stimula

1986
[The diagnostic significance of testosterone, 17-ketosteroids and estrogen secretion in male hypogonadism].
    Klinische Wochenschrift, 1965, Dec-01, Volume: 43, Issue:23

    Topics: Adult; Androsterone; Animals; Castration; Chromatography; Dehydroepiandrosterone; Estradiol; Estriol

1965
[Excretion of C-19 and C21 steroids in the urine under normal and pathological conditions of development and maturation].
    Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimentelle Chirurgie, 1967, Volume: 142, Issue:3

    Topics: 17-Ketosteroids; Adolescent; Adult; Age Factors; Androsterone; Carbon Isotopes; Child; Child, Presch

1967
[Steroid spectrum of diabetic men in relationship to their potency].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1966, Oct-01, Volume: 21, Issue:19

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Androsterone; Cortisone; Dehydroepiandrosterone;

1966
[Adolescence. I. C-19 and C21 steroid metabolism during puberty].
    Der Internist, 1967, Volume: 8, Issue:8

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Age Factors; Androgens; Carbon Isotop

1967
[Clinical and biochemical studies in a female patient with mixed gonadal dysgenesis].
    Wiener klinische Wochenschrift, 1969, Jun-20, Volume: 81, Issue:25

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Androsterone; Body

1969
Effect of aminoglutethimide on extraglandular metabolism of exogenous testosterone.
    Metabolism: clinical and experimental, 1971, Volume: 20, Issue:3

    Topics: 17-Ketosteroids; Adult; Aminoglutethimide; Androsterone; Aniline Compounds; Anticonvulsants; Dehydro

1971
The effect of chorionic gonadotropin on steroid excretion.
    Archives of internal medicine, 1971, Volume: 128, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Adolescent; Adult; Androsterone; Chorionic G

1971
The routine measurement of urinary 17-oxosteroids and 17-oxogenic steroids using gas-liquid chromatography.
    Clinica chimica acta; international journal of clinical chemistry, 1972, Volume: 40, Issue:1

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Adult; Androgens; Androsterone; Chromat

1972
Androgen production in hypogonadal men.
    The Journal of endocrinology, 1967, Volume: 37, Issue:4

    Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Androgens; Androsterone; Carbon Isotopes; Chorionic Go

1967
[Gas liquid chromatography analysis of urinary neutral steroid fractions in normal persons and patients with various diseases].
    Nihon Naibunpi Gakkai zasshi, 1970, Jun-20, Volume: 46, Issue:3

    Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormon

1970
The excretion of androsterone and etiocholanolone as a function of adrenocrotical and gonadal activity.
    Clinical biochemistry, 1972, Volume: 5, Issue:1

    Topics: Adolescent; Adrenal Glands; Adrenal Insufficiency; Adult; Aged; Androsterone; Child; Chorionic Gonad

1972
[The effect of chorionic gonadotropin on plasma testosterone in men].
    Nordisk medicin, 1969, Aug-21, Volume: 82, Issue:34

    Topics: Adolescent; Adult; Aged; Androsterone; Chorionic Gonadotropin; Estriol; Etiocholanolone; Humans; Hyp

1969