Page last updated: 2024-11-07

etiocholanolone and Granulomatosis with Polyangiitis

etiocholanolone has been researched along with Granulomatosis with Polyangiitis in 1 studies

Etiocholanolone: The 5-beta-reduced isomer of ANDROSTERONE. Etiocholanolone is a major metabolite of TESTOSTERONE and ANDROSTENEDIONE in many mammalian species including humans. It is excreted in the URINE.
3alpha-hydroxy-5beta-androstan-17-one : An androstanoid that is 5beta-androstane substituted by an alpha-hydroxy group at position 3 and an oxo group at position 17. It is a metabolite of testosterone in mammals.

Granulomatosis with Polyangiitis: A multisystemic disease of a complex genetic background. It is characterized by inflammation of the blood vessels (VASCULITIS) leading to damage in any number of organs. The common features include granulomatous inflammation of the RESPIRATORY TRACT and KIDNEYS. Most patients have measurable autoantibodies (ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES) against MYELOBLASTIN.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dale, DC1
Fauci, AS1
Guerry D, IV1
Wolff, SM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase I/II Gene Transfer Clinical Trial of rAAV9.CMV.hNAGLU for Mucopolysaccharidosis (MPS) IIIB[NCT03315182]Phase 1/Phase 211 participants (Actual)Interventional2017-10-16Terminated (stopped due to Abeona has decided to discontinue development activities for Product ABO-101 due to a lack of drug supply and for business reasons unrelated to the product safety profile and/or signs of efficacy)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for etiocholanolone and Granulomatosis with Polyangiitis

ArticleYear
Comparison of agents producing a neutrophilic leukocytosis in man. Hydrocortisone, prednisone, endotoxin, and etiocholanolone.
    The Journal of clinical investigation, 1975, Volume: 56, Issue:4

    Topics: Adult; Bone Marrow; Bone Marrow Cells; Chronic Disease; Cyclophosphamide; Dose-Response Relationship

1975