etiocholanolone has been researched along with Disease Models, Animal in 4 studies
Etiocholanolone: The 5-beta-reduced isomer of ANDROSTERONE. Etiocholanolone is a major metabolite of TESTOSTERONE and ANDROSTENEDIONE in many mammalian species including humans. It is excreted in the URINE.
3alpha-hydroxy-5beta-androstan-17-one : An androstanoid that is 5beta-androstane substituted by an alpha-hydroxy group at position 3 and an oxo group at position 17. It is a metabolite of testosterone in mammals.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Istaroxime failed to increase SERCA activity in skeletal muscle microsomes devoid of phospholamban." | 5.35 | Modulation of sarcoplasmic reticulum function by PST2744 [istaroxime; (E,Z)-3-((2-aminoethoxy)imino) androstane-6,17-dione hydrochloride)] in a pressure-overload heart failure model. ( Alemanni, M; Altomare, C; Barassi, P; Chisci, R; Ferrari, P; Micheletti, R; Mostacciuolo, G; Rocchetti, M; Zaza, A, 2008) |
| "Istaroxime failed to increase SERCA activity in skeletal muscle microsomes devoid of phospholamban." | 1.35 | Modulation of sarcoplasmic reticulum function by PST2744 [istaroxime; (E,Z)-3-((2-aminoethoxy)imino) androstane-6,17-dione hydrochloride)] in a pressure-overload heart failure model. ( Alemanni, M; Altomare, C; Barassi, P; Chisci, R; Ferrari, P; Micheletti, R; Mostacciuolo, G; Rocchetti, M; Zaza, A, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Kamel, SM | 1 |
| van Opbergen, CJM | 1 |
| Koopman, CD | 1 |
| Verkerk, AO | 1 |
| Boukens, BJD | 1 |
| de Jonge, B | 1 |
| Onderwater, YL | 1 |
| van Alebeek, E | 1 |
| Chocron, S | 1 |
| Polidoro Pontalti, C | 1 |
| Weuring, WJ | 1 |
| Vos, MA | 1 |
| de Boer, TP | 1 |
| van Veen, TAB | 1 |
| Bakkers, J | 1 |
| Rocchetti, M | 1 |
| Alemanni, M | 1 |
| Mostacciuolo, G | 1 |
| Barassi, P | 1 |
| Altomare, C | 1 |
| Chisci, R | 1 |
| Micheletti, R | 1 |
| Ferrari, P | 1 |
| Zaza, A | 1 |
| Kaminski, RM | 1 |
| Marini, H | 1 |
| Kim, WJ | 1 |
| Rogawski, MA | 1 |
4 other studies available for etiocholanolone and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Istaroxime treatment ameliorates calcium dysregulation in a zebrafish model of phospholamban R14del cardiomyopathy.
Topics: Animals; Calcium; Calcium-Binding Proteins; Cardiomyopathy, Dilated; Disease Models, Animal; Echocar | 2021 |
Modulation of sarcoplasmic reticulum function by PST2744 [istaroxime; (E,Z)-3-((2-aminoethoxy)imino) androstane-6,17-dione hydrochloride)] in a pressure-overload heart failure model.
Topics: Animals; Disease Models, Animal; Etiocholanolone; Guinea Pigs; Heart Failure; Myocytes, Cardiac; Sar | 2008 |
Anticonvulsant activity of androsterone and etiocholanolone.
Topics: 4-Aminopyridine; Androsterone; Animals; Anticonvulsants; Behavior, Animal; Disease Models, Animal; D | 2005 |