Page last updated: 2024-11-07

etiocholanolone and Chronic Disease

etiocholanolone has been researched along with Chronic Disease in 10 studies

Etiocholanolone: The 5-beta-reduced isomer of ANDROSTERONE. Etiocholanolone is a major metabolite of TESTOSTERONE and ANDROSTENEDIONE in many mammalian species including humans. It is excreted in the URINE.
3alpha-hydroxy-5beta-androstan-17-one : An androstanoid that is 5beta-androstane substituted by an alpha-hydroxy group at position 3 and an oxo group at position 17. It is a metabolite of testosterone in mammals.

Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
"A 70-year-old woman with cyclic neutropenia was treated with 16 mg of etiocholanolone and 25 mg of prednisolone intramuscularly every other day."7.66Correction of human cyclic neutropenia with prednisolone. ( Dale, DC; Fauci, AS; Wolff, SM; Wright, DG, 1978)
"A 70-year-old woman with cyclic neutropenia was treated with 16 mg of etiocholanolone and 25 mg of prednisolone intramuscularly every other day."3.66Correction of human cyclic neutropenia with prednisolone. ( Dale, DC; Fauci, AS; Wolff, SM; Wright, DG, 1978)
"Diurnal variations of plasma testosterone and urinary excretion rates of testosterone-, androsterone-, aetiocholanolone-, and DHA-glucuronide, as well as DHA-sulphate were measured before and after selective Leydig-cell stimulation (with 3 X 5000 IU human gonadotrophin) in eight patients with alcoholic liver cirrhosis, ten with acute hepatitis and four with haemochromatosis."3.65[Androgen metabolism and Leydig-cell function in acute and chronic liver disease (author's transl)]. ( Gerdes, H; Littmann, KP; Martini, GA, 1975)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-199010 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Littmann, KP1
Gerdes, H1
Martini, GA1
Ludwig, H1
Spiteller, G1
Matthaei, D1
Scheler, F1
Wright, DG1
Fauci, AS2
Dale, DC2
Wolff, SM2
Guerry D, IV1
Landyshev, IuS1
Mishuk, VP1
Gardner, FH1
Juneja, HS1
Solomon, D1
Strummer, D1
Nair, PP1
Tourney, G1
Hatfield, LM1
Essers, U1
Bleifeld, W1
Kaiser, E1
Mühler, E1
Janoschek, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase I/II Gene Transfer Clinical Trial of rAAV9.CMV.hNAGLU for Mucopolysaccharidosis (MPS) IIIB[NCT03315182]Phase 1/Phase 211 participants (Actual)Interventional2017-10-16Terminated (stopped due to Abeona has decided to discontinue development activities for Product ABO-101 due to a lack of drug supply and for business reasons unrelated to the product safety profile and/or signs of efficacy)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

10 other studies available for etiocholanolone and Chronic Disease

ArticleYear
[Androgen metabolism and Leydig-cell function in acute and chronic liver disease (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1975, Sep-19, Volume: 100, Issue:38

    Topics: Acute Disease; Adult; Aged; Androgens; Androsterone; Chorionic Gonadotropin; Chronic Disease; Circad

1975
[Profiles in chronic diseases. I. Investigations of steroid profiles in uremia (author's transl)].
    Journal of chromatography, 1978, Nov-01, Volume: 146, Issue:3

    Topics: Androstenediols; Androsterone; Chronic Disease; Dehydroepiandrosterone; Etiocholanolone; Humans; Ure

1978
Correction of human cyclic neutropenia with prednisolone.
    The New England journal of medicine, 1978, Feb-09, Volume: 298, Issue:6

    Topics: Aged; Agranulocytosis; Chronic Disease; Drug Therapy, Combination; Etiocholanolone; Female; Humans;

1978
Comparison of agents producing a neutrophilic leukocytosis in man. Hydrocortisone, prednisone, endotoxin, and etiocholanolone.
    The Journal of clinical investigation, 1975, Volume: 56, Issue:4

    Topics: Adult; Bone Marrow; Bone Marrow Cells; Chronic Disease; Cyclophosphamide; Dose-Response Relationship

1975
[Functional status of the hypophyseal-gonadal system in patients with chronic bronchitis].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:4

    Topics: 17-Ketosteroids; Adult; Androsterone; Bronchitis; Chronic Disease; Etiocholanolone; Follicle Stimula

1986
Androstane therapy to treat aplastic anaemia in adults: an uncontrolled pilot study.
    British journal of haematology, 1987, Volume: 65, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Androstanes; Anemia, Aplastic; Chronic Disease; Colony-Formi

1987
Relationship between vitamin E and urinary excretion of ketosteroid fractions in cystic mastitis.
    Annals of the New York Academy of Sciences, 1972, Dec-18, Volume: 203

    Topics: 17-Ketosteroids; Adult; Androsterone; Chronic Disease; Cysts; Dehydroepiandrosterone; Estrogens; Eti

1972
Androgen metabolism in schizophrenics, homosexuals, and normal controls.
    Biological psychiatry, 1973, Volume: 6, Issue:1

    Topics: 17-Ketosteroids; Adolescent; Adult; Age Factors; Androgens; Androstanes; Androsterone; Chronic Disea

1973
[Recurrent fever and raise of free etiocholanolone in the blood. Report on five patients].
    Deutsche medizinische Wochenschrift (1946), 1971, Jan-15, Volume: 96, Issue:3

    Topics: Adult; Chromatography, Thin Layer; Chronic Disease; Etiocholanolone; Female; Fever; Humans; Leukocyt

1971
[Etiocholanone fever and liver diseases].
    Die Medizinische Welt, 1968, Mar-23, Volume: 12

    Topics: Adult; Chronic Disease; Etiocholanolone; Fever; Hepatitis; Humans; Male

1968