Page last updated: 2024-11-07

etiocholanolone and Cancer of Prostate

etiocholanolone has been researched along with Cancer of Prostate in 16 studies

Etiocholanolone: The 5-beta-reduced isomer of ANDROSTERONE. Etiocholanolone is a major metabolite of TESTOSTERONE and ANDROSTENEDIONE in many mammalian species including humans. It is excreted in the URINE.
3alpha-hydroxy-5beta-androstan-17-one : An androstanoid that is 5beta-androstane substituted by an alpha-hydroxy group at position 3 and an oxo group at position 17. It is a metabolite of testosterone in mammals.

Research Excerpts

ExcerptRelevanceReference
"The survival and progression of prostate cancer are generally dependent on expression of the androgen receptor (AR), as well as the availability of endogenous AR agonists."2.48The 5α-androstanedione pathway to dihydrotestosterone in castration-resistant prostate cancer. ( Sharifi, N, 2012)
"Inanition and obesity have been shown to alter steroid metabolism but it is not known whether nutritional "microdifferences" (i."2.35Hormone profiles in hormone-dependent cancers. ( Bradlow, HL; Fishman, J; Hellman, L; Zumoff, B, 1975)
"Almost all prostate cancers recur during androgen deprivation therapy, and new evidence suggests that androgen receptor activation persists despite castrate levels of circulating androgens."1.36Atmospheric pressure photoionization tandem mass spectrometry of androgens in prostate cancer. ( Lih, FB; Mohler, JL; Titus, MA; Tomer, KB, 2010)
"In these prostatic cancer patients, plasma androgen levels decreased, while estrogen levels increased."1.26Effect of diet on plasma and urinary hormones in South African black men with prostatic cancer. ( Garbaczewski, L; Hill, P; Walker, AR; Wynder, EL, 1982)
"In patients with breast and prostate cancer hormone excretion patterns differ in a similar way from patterns in persons without cancer."1.24HORMONE EXCRETION PATTERNS IN BREAST AND PROSTATE CANCER ARE ABNORMAL. ( HOPKINS, CE; MARMORSTON, J; STERN, E; WEINER, JM, 1964)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19909 (56.25)18.7374
1990's2 (12.50)18.2507
2000's0 (0.00)29.6817
2010's4 (25.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
DE Luca, S1
Amante, E1
Fiori, C1
Alleva, G1
Alladio, E1
Marini, F1
Garrou, D1
Manfredi, M1
Amparore, D1
Checcucci, E1
Pruner, S1
Salomone, A1
Scarpa, RM1
Vincenti, M1
Porpiglia, F1
Alevizopoulos, K1
Dimas, K1
Papadopoulou, N1
Schmidt, EM1
Tsapara, A1
Alkahtani, S1
Honisch, S1
Prousis, KC1
Alarifi, S1
Calogeropoulou, T1
Lang, F1
Stournaras, C1
Lih, FB1
Titus, MA1
Mohler, JL1
Tomer, KB1
Sharifi, N2
BRADSHAW, LR1
BAGNESS, JE1
PYRAH, LN1
RAPER, FP1
STERN, E2
HOPKINS, CE2
WEINER, JM1
MARMORSTON, J2
LOMBARDO, LJ1
MYERS, SM1
GIERSON, H1
Hill, P1
Wynder, EL1
Garbaczewski, L1
Walker, AR1
Délos, S1
Carsol, JL1
Ghazarossian, E1
Raynaud, JP1
Martin, PM1
Negri-Cesi, P1
Colciago, A1
Poletti, A1
Motta, M1
Zumoff, B1
Fishman, J1
Bradlow, HL1
Hellman, L1
Garnham, JR1
Bulbrook, RD1
Wang, DY1
Bird, CE1
Clark, AF1
Harkness, RA1
Bell, ET1
Loraine, JA1
Ismail, AA1
Morse, WI1

Reviews

3 reviews available for etiocholanolone and Cancer of Prostate

ArticleYear
Clinical implications of the 5α-androstanedione pathway for castration-resistant prostate cancer.
    Future oncology (London, England), 2011, Volume: 7, Issue:11

    Topics: 3-Hydroxysteroid Dehydrogenases; Abiraterone Acetate; Androstadienes; Androstenediol; Antineoplastic

2011
The 5α-androstanedione pathway to dihydrotestosterone in castration-resistant prostate cancer.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2012, Volume: 60, Issue:2

    Topics: Abiraterone Acetate; Androstadienes; Biosynthetic Pathways; Dihydrotestosterone; Etiocholanolone; Hu

2012
Hormone profiles in hormone-dependent cancers.
    Cancer research, 1975, Volume: 35, Issue:11 Pt. 2

    Topics: Adrenalectomy; Adult; Age Factors; Androgens; Androsterone; Breast Neoplasms; China; Epidemiologic M

1975

Trials

1 trial available for etiocholanolone and Cancer of Prostate

ArticleYear
The effects of clomiphene on endocrine function in male patients with adrenocortical infufficiency and following castration.
    Acta endocrinologica, 1968, Volume: 58, Issue:1

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Adrenal Glands; Adrenal Insufficiency;

1968

Other Studies

12 other studies available for etiocholanolone and Cancer of Prostate

ArticleYear
Prospective evaluation of urinary steroids and prostate carcinoma-induced deviation: preliminary results.
    Minerva urology and nephrology, 2021, Volume: 73, Issue:1

    Topics: Aged; Biomarkers; Dehydroepiandrosterone; Etiocholanolone; Gas Chromatography-Mass Spectrometry; Hum

2021
Functional characterization and anti-cancer action of the clinical phase II cardiac Na+/K+ ATPase inhibitor istaroxime: in vitro and in vivo properties and cross talk with the membrane androgen receptor.
    Oncotarget, 2016, Apr-26, Volume: 7, Issue:17

    Topics: Animals; Apoptosis; Cell Line; Cell Line, Tumor; Cell Proliferation; Clinical Trials, Phase II as To

2016
Atmospheric pressure photoionization tandem mass spectrometry of androgens in prostate cancer.
    Analytical chemistry, 2010, Jul-15, Volume: 82, Issue:14

    Topics: Androgens; Atmospheric Pressure; Chromatography, High Pressure Liquid; Dihydrotestosterone; Etiochol

2010
A STUDY OF STEROID EXCRETION IN PATIENTS WITH PROSTATIC CANCER.
    Investigative urology, 1964, Volume: 1

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Androsterone; Biopsy; Cortisone; Dehydroepiandrosterone; D

1964
HORMONE EXCRETION PATTERNS IN BREAST AND PROSTATE CANCER ARE ABNORMAL.
    Science (New York, N.Y.), 1964, Aug-14, Volume: 145, Issue:3633

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Aged; Androsterone; Breast Neoplasms; Creatine; Creatinine

1964
URINARY EXCRETION OF NEUTRAL 17-KETOSTEROIDS AND PREGNANEDIOL BY PATIENTS WITH PROSTATIC CANCER AND BENIGN PROSTATIC HYPERTROPHY.
    The Journal of urology, 1965, Volume: 93

    Topics: 17-Ketosteroids; Androsterone; Blood Glucose; Blood Urea Nitrogen; Creatine; Creatinine; Etiocholano

1965
Effect of diet on plasma and urinary hormones in South African black men with prostatic cancer.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: Aged; Androgens; Androsterone; Black People; Dehydroepiandrosterone; Diet; Estriol; Estrogens; Estro

1982
Testosterone metabolism in primary cultures of human prostate epithelial cells and fibroblasts.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:3-4

    Topics: 17-Hydroxysteroid Dehydrogenases; Adenosarcoma; Androstenedione; Azasteroids; Blotting, Northern; Ce

1995
5alpha-reductase isozymes and aromatase are differentially expressed and active in the androgen-independent human prostate cancer cell lines DU145 and PC3.
    The Prostate, 1999, Dec-01, Volume: 41, Issue:4

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Anastrozole; Androgens; Androstenedione; Aromatase; Aromatase

1999
Hormone profiles and discriminant functions in cancer.
    Lancet (London, England), 1970, Nov-21, Volume: 2, Issue:7682

    Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Breast Neoplasms; Etiocholanolone; Female; Human

1970
Conjugated and unconjugated dehydroepiandrosterone, aetiocholanolone and androsterone in the peripheral plasma of patients with cancer of the breast, ovary, uterus or prostate.
    European journal of cancer, 1969, Volume: 5, Issue:3

    Topics: Adult; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Male

1969
A single method for determination of urine steroids. I. Levels of testosterone, epitestosterone and 17-ketosteroid fractions. II. Specific activities of testosterone, androsterone and etiocholanolone and production rate of testosterone following administr
    Clinical biochemistry, 1970, Volume: 3, Issue:3

    Topics: 17-Ketosteroids; Adolescent; Adult; Aged; Androsterone; Breast Neoplasms; Carbon Isotopes; Carcinoma

1970