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etiocholanolone and Anemia, Aplastic

etiocholanolone has been researched along with Anemia, Aplastic in 9 studies

Etiocholanolone: The 5-beta-reduced isomer of ANDROSTERONE. Etiocholanolone is a major metabolite of TESTOSTERONE and ANDROSTENEDIONE in many mammalian species including humans. It is excreted in the URINE.
3alpha-hydroxy-5beta-androstan-17-one : An androstanoid that is 5beta-androstane substituted by an alpha-hydroxy group at position 3 and an oxo group at position 17. It is a metabolite of testosterone in mammals.

Anemia, Aplastic: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.

Research Excerpts

ExcerptRelevanceReference
"A patient with aplastic anemia, who had been unresponsive to androgens, antithymocyte globulin, high-dose methylprednisolone, and cyclosporine, responded to treatment with 3-beta-etiocholanolone, nandrolone decanoate, and prednisolone acetate."1.28Successful treatment of severe refractory aplastic anemia with 3-beta etiocholanolone and nandrolone decanoate. ( Gardner, FH; Seewald, TR; Zeigler, ZR, 1989)
"All patients except one with aplastic anaemia responded with an increase in reticulocytes, haematocrit, red blood cell mass, and blood neutrophils and platelets."1.26Aetiocholanolone and prednisolone therapy in patients with severe bone-marrow failure. ( Besa, EC; Dale, DC; Gardner, FH; Wolff, SM, 1977)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19909 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Najean, Y1
Chedeville, A1
Eberlin, A1
Balitrand, N1
Juneja, HS2
Gardner, FH5
Minguell, JJ1
Helmer, RE1
Ippoliti, G1
Invernizzi, R1
Marini, G1
Carnevale-Maffé, G1
Girino, M1
Casirola, G1
Besa, EC1
Wolff, SM1
Dale, DC1
Heimpel, H1
Seewald, TR1
Zeigler, ZR1
Fawcett, HD1
Sayle, BA1
Nusynowitz, ML1
Claustres, M1
Margueritte, G1
Sultan, C1

Other Studies

9 other studies available for etiocholanolone and Anemia, Aplastic

ArticleYear
A study of the efficacy of 5 alpha- and 5 beta-androstanes in chronic experimental aplastic anemia in mice.
    Nouvelle revue francaise d'hematologie, 1984, Volume: 26, Issue:6

    Topics: Androsterone; Anemia, Aplastic; Animals; Bone Marrow; Bone Marrow Cells; Etiocholanolone; Female; Mi

1984
Abnormal marrow fibroblasts in aplastic anemia.
    Experimental hematology, 1984, Volume: 12, Issue:4

    Topics: Anemia, Aplastic; Bone Marrow; Cell Division; Cells, Cultured; Colony-Forming Units Assay; Dexametha

1984
[Etiocholanolone-prednisolone combination in the therapy of certain bone marrow insufficiency diseases].
    Haematologica, 1980, Volume: 65, Issue:3

    Topics: Anemia, Aplastic; Drug Therapy, Combination; Etiocholanolone; Humans; Prednisolone

1980
Aetiocholanolone and prednisolone therapy in patients with severe bone-marrow failure.
    Lancet (London, England), 1977, Apr-02, Volume: 1, Issue:8014

    Topics: Adult; Aged; Anemia, Aplastic; Blood Cell Count; Cell Survival; Drug Combinations; Etiocholanolone;

1977
Stimulation of hemopoiesis in aplastic anemia by hormones and other agents.
    Haematology and blood transfusion, 1979, Volume: 24

    Topics: Adrenal Cortex Hormones; Androgens; Anemia, Aplastic; Cobalt; Etiocholanolone; Growth Hormone; Hemat

1979
Successful treatment of severe refractory aplastic anemia with 3-beta etiocholanolone and nandrolone decanoate.
    American journal of hematology, 1989, Volume: 31, Issue:3

    Topics: Anemia, Aplastic; Blood Cell Count; Drug Resistance; Drug Therapy, Combination; Etiocholanolone; Fem

1989
Unusual pattern of marrow distribution following treatment of aplastic anemia.
    Clinical nuclear medicine, 1989, Volume: 14, Issue:6

    Topics: Anemia, Aplastic; Bone Marrow; Etiocholanolone; Female; Humans; Middle Aged; Radionuclide Imaging

1989
Androstane therapy to treat aplastic anaemia in adults: an uncontrolled pilot study.
    British journal of haematology, 1987, Volume: 65, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Androstanes; Anemia, Aplastic; Chronic Disease; Colony-Formi

1987
In vitro CFU-E and BFU-E responses to androgen in bone marrow from children with primary hypoproliferative anaemia: a possible therapeutic assay.
    European journal of pediatrics, 1986, Volume: 144, Issue:5

    Topics: Androgens; Anemia, Aplastic; Bone Marrow; Child; Child, Preschool; Colony-Forming Units Assay; Eryth

1986