Page last updated: 2024-11-07

etiocholanolone and 48,XXYY Syndrome

etiocholanolone has been researched along with 48,XXYY Syndrome in 7 studies

Etiocholanolone: The 5-beta-reduced isomer of ANDROSTERONE. Etiocholanolone is a major metabolite of TESTOSTERONE and ANDROSTENEDIONE in many mammalian species including humans. It is excreted in the URINE.
3alpha-hydroxy-5beta-androstan-17-one : An androstanoid that is 5beta-androstane substituted by an alpha-hydroxy group at position 3 and an oxo group at position 17. It is a metabolite of testosterone in mammals.

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
OKANO, K1
MATSUMOTO, K1
AKEHI, A1
MIZUTANI, S1
KIKKAWA, H1
SEKI, T1
Rivera, R1
Dorfman, RI1
Forchielli, E1
Scurry, MT1
Bruton, J1
Barry, KG1
Garmendia, F1
Nicolis, GL1
Gabrilove, JL1
Froland, A1
Frandsen, VA1
Johnsen, SG1
Jeffcoate, SL1
Brooks, RV1
Lim, NY1
London, DR1
Prunty, FT1
Spathis, GS1
Gleispach, H1
Glatzl, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Aromatase Inhibition and Testosterone Replacement in Sex Steroids, Pituitary Hormones, Markers of Bone Turnover, Muscle Strength, and Cognition in Older Men[NCT00104572]Phase 244 participants (Actual)Interventional2004-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Effect of Testosterone Gel vs. Anastrozole on Bone Mineral Density

bone mineral density lumbar spine for all arms testosterone gel, anastrozole and placebo (NCT00104572)
Timeframe: 1 year

Interventiong/cm2 (Mean)
Transdermal Testosterone0.042
Aromatase Inhibitor0.008
Placebo0.047

Effect of Testosterone Gel vs. Anastrozole on Glucose Tolerance/Lipid Metabolism

"Primary outcome HOMA-IR for all groups testosterone gel, anastrozole and placebo Insulin resistance measure by HOMA-IR is a score if a person is insulin resistance the score should be between minimum 0.7- maximum 2 or more.~Absolute changes in HOMAIR in all treatment arms, calculation time frame 1 year minus baseline point." (NCT00104572)
Timeframe: 1 year

Interventionscore on a scale (Mean)
Transdermal Testosterone-0.05
Aromatase Inhibitor0.15
Placebo-0.11

Effect of Testosterone Gel vs. Anastrozole on Prostate Volume/Prostate Specific Antigen Levels/Urinary Function

"rectal ultrasound prostate volume for all groups testosterone gel, anastrozole and placebo.~Absolute changes in prostate volume in all treatment arms, calculation time frame 1 year minus baseline point." (NCT00104572)
Timeframe: 1 year

Interventioncc (Mean)
Transdermal Testosterone4.5
Aromatase Inhibitor-1.66
Placebo-1.05

Effect of Testosterone Gel vs. Anastrozole on Pulsatile Growth Hormone Release

Overnight Growth hormone measures (total hormone secretion) for groups testosterone gel, anastrozole and placebo (NCT00104572)
Timeframe: 1 year

Interventionng/ml/8h (Mean)
Transdermal Testosterone5.8
Aromatase Inhibitor10
Placebo7.7

Other Studies

7 other studies available for etiocholanolone and 48,XXYY Syndrome

ArticleYear
STUDIES ON THE URINARY STEROIDS IN BILATERAL GYNECOMASTIA.
    Endocrinologia japonica, 1963, Volume: 10

    Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Neoplasms; Androsterone; Estradiol; Estriol; Estrone; Eti

1963
A modified method for the analysis of urinary 17-ketosteroids, pregnanediol and pregnanetriol by gas liquid chromatography in normal subjects and subjects with various endocrine disorders.
    Acta endocrinologica, 1967, Volume: 54, Issue:1

    Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Androsterone; Chromatography, Gas; Cushing Syndrom

1967
The effect of chorionic gonadotropin on steroid excretion.
    Archives of internal medicine, 1971, Volume: 128, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Adolescent; Adult; Androsterone; Chorionic G

1971
The determination of urinary pregnanetriol and the neutral 17-ketosteroids by gas-liquid chromatography.
    Steroids, 1971, Volume: 18, Issue:2

    Topics: 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adre

1971
Adrenal and gonadal contribution to androgen and oestrogen excretion in Klinefelter's syndrome.
    Acta endocrinologica, 1973, Volume: 72, Issue:1

    Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adult; Androsterone; Dehydroepiandrosterone; D

1973
Androgen production in hypogonadal men.
    The Journal of endocrinology, 1967, Volume: 37, Issue:4

    Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Androgens; Androsterone; Carbon Isotopes; Chorionic Go

1967
[Hormone examination in children with Klinefelter's syndrome].
    Wiener klinische Wochenschrift, 1969, Nov-07, Volume: 81, Issue:45

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Age Factors; An

1969