etilefrine has been researched along with Anemia, Sickle Cell in 8 studies
Etilefrine: A phenylephrine-related beta-1 adrenergic and alpha adrenergic agonist used as a cardiotonic and antihypotensive agent.
Anemia, Sickle Cell: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intracavernous injections of etilefrine were effective in seven children with acute sickle cell priapism, and stuttering priapism resolved in five children after one to seven months of oral etilefrine." | 7.71 | Management of sickle cell priapism with etilefrine. ( Assimadi, JK; Atakouma, Y; Gbadoé, AD; Kusiaku, K, 2001) |
| "Priapism is a common and currently unsatisfactorily managed complication of sickle cell disease (SCD)." | 6.68 | Preventive treatment of priapism in sickle cell disease with oral and self-administered intracavernous injection of etilefrine. ( Bachir, D; Galacteros, F; Lee, K; Virag, R, 1996) |
| "Priapism is a common complication of sickle cell disease (SCD) that could lead to erectile dysfunction and psychosocial problems." | 5.31 | Etilefrine for the prevention of priapism in adult sickle cell disease. ( Cheung, B; Jegede, T; Okpala, I; Westerdale, N, 2002) |
| " Whereas the orally administrable iron-chelating agent deferasirox is likely to increasingly take the place of desferioxamine (which can only be given parenterally), effective treatment of priapism in SCD remains a distressing challenge." | 4.83 | Investigational agents for sickle cell disease. ( Okpala, I, 2006) |
| "Intracavernous injections of etilefrine were effective in seven children with acute sickle cell priapism, and stuttering priapism resolved in five children after one to seven months of oral etilefrine." | 3.71 | Management of sickle cell priapism with etilefrine. ( Assimadi, JK; Atakouma, Y; Gbadoé, AD; Kusiaku, K, 2001) |
| "Ischemic priapism is a common but underrecognized morbidity affecting about 33% of adult men with sickle cell disease (SCD)." | 2.82 | Epidemiology and treatment of priapism in sickle cell disease. ( Burnett, AL; DeBaun, MR; Idris, IM, 2022) |
| "Priapism is a common and currently unsatisfactorily managed complication of sickle cell disease (SCD)." | 2.68 | Preventive treatment of priapism in sickle cell disease with oral and self-administered intracavernous injection of etilefrine. ( Bachir, D; Galacteros, F; Lee, K; Virag, R, 1996) |
| "Priapism affects up to half of all men with sickle cell disease, however, there is no consistency in treatment." | 2.66 | Treatments for priapism in boys and men with sickle cell disease. ( Anie, KA; Chinegwundoh, FI; Smith, S, 2020) |
| "Priapism is a urological emergency which is commonly classified into low-flow and high-flow priapism." | 2.44 | Stuttering priapism--a review of the therapeutic options. ( Arya, M; Minhas, S; Muneer, A; Ralph, DJ, 2008) |
| "Priapism is a common complication of sickle cell disease (SCD) that could lead to erectile dysfunction and psychosocial problems." | 1.31 | Etilefrine for the prevention of priapism in adult sickle cell disease. ( Cheung, B; Jegede, T; Okpala, I; Westerdale, N, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Idris, IM | 2 |
| Burnett, AL | 2 |
| DeBaun, MR | 2 |
| Chinegwundoh, FI | 1 |
| Smith, S | 1 |
| Anie, KA | 1 |
| Okpala, I | 2 |
| Westerdale, N | 1 |
| Jegede, T | 1 |
| Cheung, B | 1 |
| Muneer, A | 1 |
| Minhas, S | 1 |
| Arya, M | 1 |
| Ralph, DJ | 1 |
| Virag, R | 1 |
| Bachir, D | 1 |
| Lee, K | 1 |
| Galacteros, F | 1 |
| Gbadoe, AD | 2 |
| Akakpo-Vidah, A | 1 |
| Pitche, P | 1 |
| Assimadi, JK | 2 |
| Atakouma, Y | 1 |
| Kusiaku, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Double-Blind Trial for Prevention of Recurrent Ischemic Priapism in Men With Sickle Cell Disease: A Pilot Study[NCT05142254] | Phase 2 | 64 participants (Actual) | Interventional | 2022-04-01 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for etilefrine and Anemia, Sickle Cell
| Article | Year |
|---|---|
Epidemiology and treatment of priapism in sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Clinical Trials, Phase II as Topic; Etilefrine; Hemolysis; Humans; Male; | 2022 |
Epidemiology and treatment of priapism in sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Clinical Trials, Phase II as Topic; Etilefrine; Hemolysis; Humans; Male; | 2022 |
Epidemiology and treatment of priapism in sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Clinical Trials, Phase II as Topic; Etilefrine; Hemolysis; Humans; Male; | 2022 |
Epidemiology and treatment of priapism in sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Clinical Trials, Phase II as Topic; Etilefrine; Hemolysis; Humans; Male; | 2022 |
Treatments for priapism in boys and men with sickle cell disease.
Topics: Adrenergic Agents; Anemia, Sickle Cell; Diethylstilbestrol; Ephedrine; Estrogens, Non-Steroidal; Eti | 2020 |
Investigational agents for sickle cell disease.
Topics: Acetamides; Anemia, Sickle Cell; Animals; Antihypertensive Agents; Antisickling Agents; Benzaldehyde | 2006 |
Stuttering priapism--a review of the therapeutic options.
Topics: Anemia, Sickle Cell; Digoxin; Drug Delivery Systems; Etilefrine; Hormones; Humans; Male; Orchiectomy | 2008 |
1 trial available for etilefrine and Anemia, Sickle Cell
| Article | Year |
|---|---|
Preventive treatment of priapism in sickle cell disease with oral and self-administered intracavernous injection of etilefrine.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Adult; Anemia, Sickle Cell; Etilefrine; Humans; Inj | 1996 |
3 other studies available for etilefrine and Anemia, Sickle Cell
| Article | Year |
|---|---|
Etilefrine for the prevention of priapism in adult sickle cell disease.
Topics: Adrenergic alpha-Agonists; Adult; Anemia, Sickle Cell; Etilefrine; Follow-Up Studies; Humans; Male; | 2002 |
[Sickle cell disease priapism: treatment with intracavernous injections of etilefrine].
Topics: Adolescent; Adrenergic Agonists; Adult; Anemia, Sickle Cell; Child; Etilefrine; Humans; Injections; | 2000 |
Management of sickle cell priapism with etilefrine.
Topics: Administration, Oral; Adolescent; Adrenergic alpha-Agonists; Anemia, Sickle Cell; Child; Child, Pres | 2001 |