etifoxine has been researched along with Cerebral-Hemorrhage* in 1 studies
1 other study(ies) available for etifoxine and Cerebral-Hemorrhage
Article | Year |
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A TSPO ligand attenuates brain injury after intracerebral hemorrhage.
Intracerebral hemorrhage (ICH) is a devastating disease without effective treatment. After ICH, the immediate infiltration of leukocytes and activation of microglia are accompanied by a rapid up-regulation of the 18-kDa translocator protein (TSPO). TSPO ligands have shown anti-inflammatory and neuroprotective properties in models of CNS injury. In this study, we determined the impact of a TSPO ligand, etifoxine, on brain injury and inflammation in 2 mouse models of ICH. TSPO was up-regulated in Iba1 Topics: Animals; Anti-Anxiety Agents; Brain Edema; Cerebral Hemorrhage; Cytokines; Gene Expression Regulation; Mice; Oxazines; Receptors, GABA; Up-Regulation | 2017 |