etifoxine and Amnesia--Anterograde

etifoxine has been researched along with Amnesia--Anterograde* in 1 studies

Trials

1 trial(s) available for etifoxine and Amnesia--Anterograde

Article	Year
A double blind parallel group placebo controlled comparison of sedative and mnesic effects of etifoxine and lorazepam in healthy subjects [corrected]. Fundamental & clinical pharmacology, 2001, Volume: 15, Issue:3 This paper describes the psychomotor and mnesic effects of single oral doses of etifoxine (50 and 100 mg) and lorazepam (2 mg) in healthy subjects. Forty-eight healthy subjects were included in this randomized double blind, placebo controlled parallel group study [corrected]. The effects of drugs were assessed by using a battery of subjective and objective tests that explored mood and vigilance (Visual Analog Scale), attention (Barrage test), psychomotor performance (Choice Reaction Time) and memory (digit span, immediate and delayed free recall of a word list). Whereas vigilance, psychomotor performance and free recall were significantly impaired by lorazepam, neither dosage of etifoxine (50 and 100 mg) produced such effects. These results suggest that 50 and 100 mg single dose of etifoxine do not induce amnesia and sedation as compared to lorazepam. Topics: Adolescent; Adult; Affect; Amnesia, Anterograde; Attention; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Memory; Motor Activity; Oxazines; Psychomotor Performance; Tranquilizing Agents	2001

Article

Year

A double blind parallel group placebo controlled comparison of sedative and mnesic effects of etifoxine and lorazepam in healthy subjects [corrected].

Fundamental & clinical pharmacology, 2001, Volume: 15, Issue:3

This paper describes the psychomotor and mnesic effects of single oral doses of etifoxine (50 and 100 mg) and lorazepam (2 mg) in healthy subjects. Forty-eight healthy subjects were included in this randomized double blind, placebo controlled parallel group study [corrected]. The effects of drugs were assessed by using a battery of subjective and objective tests that explored mood and vigilance (Visual Analog Scale), attention (Barrage test), psychomotor performance (Choice Reaction Time) and memory (digit span, immediate and delayed free recall of a word list). Whereas vigilance, psychomotor performance and free recall were significantly impaired by lorazepam, neither dosage of etifoxine (50 and 100 mg) produced such effects. These results suggest that 50 and 100 mg single dose of etifoxine do not induce amnesia and sedation as compared to lorazepam.

Topics: Adolescent; Adult; Affect; Amnesia, Anterograde; Attention; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Memory; Motor Activity; Oxazines; Psychomotor Performance; Tranquilizing Agents

2001