Page last updated: 2024-10-26

etidronate and Thrombocytopenia

etidronate has been researched along with Thrombocytopenia in 8 studies

Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.

Thrombocytopenia: A subnormal level of BLOOD PLATELETS.

Research Excerpts

ExcerptRelevanceReference
"A potential limitation of rhenium-186-1,1-hydroxyethylidene diphosphonate (186Re-HEDP) therapy in patients with painful bone metastases is thrombocytopenia."7.69Evaluation of thrombocytopenia in patients treated with rhenium-186-HEDP: guidelines for individual dosage recommendations. ( Blijham, GH; de Klerk, JM; Han, SH; Stokkel, MP; van Dijk, A; van het Schip, AD; van Rijk, PP; Zonnenberg, BA, 1994)
" A Phase 1 dosage escalation study was performed using 186Re-HEDP in patients with metastatic breast cancer."6.68Phase 1 study of rhenium-186-HEDP in patients with bone metastases originating from breast cancer. ( Blijham, GH; de Klerk, JM; Quirijnen, JM; van Dijk, A; van het Schip, AD; van Rijk, PP; Zonnenberg, BA, 1996)
"A potential limitation of rhenium-186-1,1-hydroxyethylidene diphosphonate (186Re-HEDP) therapy in patients with painful bone metastases is thrombocytopenia."3.69Evaluation of thrombocytopenia in patients treated with rhenium-186-HEDP: guidelines for individual dosage recommendations. ( Blijham, GH; de Klerk, JM; Han, SH; Stokkel, MP; van Dijk, A; van het Schip, AD; van Rijk, PP; Zonnenberg, BA, 1994)
"Twenty-nine prostatic cancer patients with multiple painful bone metastases were included in the study."2.69Can bone marrow scintigraphy predict platelet toxicity after treatment with 186Re-HEDP? ( de Klerk, JM; Huiskes, AW; van Dijk, A; van Het Schip, AD; van Rijk, PP; Zonnenberg, BA, 1999)
" A Phase 1 dosage escalation study was performed using 186Re-HEDP in patients with metastatic breast cancer."2.68Phase 1 study of rhenium-186-HEDP in patients with bone metastases originating from breast cancer. ( Blijham, GH; de Klerk, JM; Quirijnen, JM; van Dijk, A; van het Schip, AD; van Rijk, PP; Zonnenberg, BA, 1996)
"Although the function of normal bone marrow is affected by metastases in patients with metastatic bone disease, the MIRD model can be used to relate toxicity to the bone marrow absorbed dose after a therapeutic dosage of 186Re-HEDP."1.29Bone marrow absorbed dose of rhenium-186-HEDP and the relationship with decreased platelet counts. ( Blijham, GH; de Klerk, JM; Hoekstra, A; Rutgers, DH; van Dieren, EB; van Dijk, A; van het Schip, AD; van Rijk, PP; Zonnenberg, BA, 1996)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (75.00)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Scheffler, J1
Derejko, M1
Bandurski, T1
Romanowicz, G1
de Klerk, JM5
Zonnenberg, BA5
van het Schip, AD5
van Dijk, A5
Han, SH2
Quirijnen, JM2
Blijham, GH4
van Rijk, PP5
Stokkel, MP1
van Dieren, EB1
Hoekstra, A1
Rutgers, DH1
Silberstein, EB1
Huiskes, AW1
Spencer, RP1

Reviews

1 review available for etidronate and Thrombocytopenia

ArticleYear
Application of rhenium-188 HEDP in bone metastases therapy.
    Nuclear medicine review. Central & Eastern Europe, 2003, Volume: 6, Issue:1

    Topics: Bone Neoplasms; Etidronic Acid; Humans; Leukopenia; Organometallic Compounds; Pain; Palliative Care;

2003

Trials

4 trials available for etidronate and Thrombocytopenia

ArticleYear
Dose escalation study of rhenium-186 hydroxyethylidene diphosphonate in patients with metastatic prostate cancer.
    European journal of nuclear medicine, 1994, Volume: 21, Issue:10

    Topics: Aged; Bone Neoplasms; Etidronic Acid; Humans; Male; Organometallic Compounds; Palliative Care; Prost

1994
Phase 1 study of rhenium-186-HEDP in patients with bone metastases originating from breast cancer.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:2

    Topics: Alkaline Phosphatase; Bone Neoplasms; Breast Neoplasms; Carcinoembryonic Antigen; Dose-Response Rela

1996
Dosage and response in radiopharmaceutical therapy of painful osseous metastases.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:2

    Topics: Bone Neoplasms; Breast Neoplasms; Dose-Response Relationship, Radiation; Etidronic Acid; Female; Hum

1996
Can bone marrow scintigraphy predict platelet toxicity after treatment with 186Re-HEDP?
    Nuclear medicine communications, 1999, Volume: 20, Issue:9

    Topics: Aged; Blood Platelets; Bone and Bones; Bone Marrow; Bone Marrow Neoplasms; Diphosphonates; Etidronic

1999

Other Studies

3 other studies available for etidronate and Thrombocytopenia

ArticleYear
Evaluation of thrombocytopenia in patients treated with rhenium-186-HEDP: guidelines for individual dosage recommendations.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1994, Volume: 35, Issue:9

    Topics: Aged; Aged, 80 and over; Bone Neoplasms; Dose-Response Relationship, Radiation; Etidronic Acid; Huma

1994
Bone marrow absorbed dose of rhenium-186-HEDP and the relationship with decreased platelet counts.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:1

    Topics: Aged; Bone Marrow; Bone Neoplasms; Dose-Response Relationship, Radiation; Etidronic Acid; Humans; Ma

1996
Quantifying leukocyte and thrombocyte suppression-recovery after Re-186 HEDP for bone metastases.
    Clinical nuclear medicine, 2000, Volume: 25, Issue:6

    Topics: Blood Platelets; Bone Marrow; Bone Neoplasms; Breast Neoplasms; Carcinoma; Etidronic Acid; Female; F

2000