Page last updated: 2024-10-26

etidronate and Spinal Diseases

etidronate has been researched along with Spinal Diseases in 7 studies

Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.

Spinal Diseases: Diseases involving the SPINE.

Research Excerpts

ExcerptRelevanceReference
"Inhibition of skeletal mineralisation is a well-recognized complication of disodium etidronate therapy that was identified in the earliest studies of its use in osteoporosis and Paget's disease."3.70Gross vertebral collapse associated with long-term disodium etidronate treatment for pelvic Paget's disease. ( MacGowan, JR; Morris, VH; Pringle, J; Stamp, TC, 2000)
" The time course of changes in PTH levels following cessation of dosing was unaffected by calcium supplementation."2.70Effect of high doses of oral risedronate (20 mg/day) on serum parathyroid hormone levels and urinary collagen cross-link excretion in postmenopausal women with spinal osteoporosis. ( Collette, J; Eastell, R; Ethgen, D; Reginster, JY; Roumagnac, I; Russell, RG; Zegels, B, 2001)
"We conclude that treatment of postmenopausal osteoporosis with oestrogen/progestogen for 3 years results in net spinal bone gain and a positive effect on calcium balance slightly better than that of intermittent etidronate."2.67A comparison of the effects of oestrogen/progestogen, high-dose oral calcium, intermittent cyclic etidronate and an ADFR regime on calcium kinetics and bone mass in postmenopausal women with spinal osteoporosis. ( Charles, P; Hasling, C; Jensen, FT; Mosekilde, L, 1994)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hasling, C1
Charles, P1
Jensen, FT1
Mosekilde, L1
MacGowan, JR1
Pringle, J1
Morris, VH1
Stamp, TC1
Zegels, B1
Eastell, R1
Russell, RG1
Ethgen, D1
Roumagnac, I1
Collette, J1
Reginster, JY1
Sahota, O1
Fowler, I1
Blackwell, PJ1
Lawson, N1
Cawte, SA1
San, P1
Masud, T1
Hosking, DJ1
Oppenheim, BE1
Cantez, S1
Tanno, T1
Moser, E1

Trials

3 trials available for etidronate and Spinal Diseases

ArticleYear
A comparison of the effects of oestrogen/progestogen, high-dose oral calcium, intermittent cyclic etidronate and an ADFR regime on calcium kinetics and bone mass in postmenopausal women with spinal osteoporosis.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1994, Volume: 4, Issue:4

    Topics: Administration, Oral; Aged; Bone Density; Calcium; Drug Administration Schedule; Drug Therapy, Combi

1994
Effect of high doses of oral risedronate (20 mg/day) on serum parathyroid hormone levels and urinary collagen cross-link excretion in postmenopausal women with spinal osteoporosis.
    Bone, 2001, Volume: 28, Issue:1

    Topics: Aged; Calcium Channel Blockers; Collagen; Cross-Linking Reagents; Double-Blind Method; Etidronic Aci

2001
A comparison of continuous alendronate, cyclical alendronate and cyclical etidronate with calcitriol in the treatment of postmenopausal vertebral osteoporosis: a randomized controlled trial.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2000, Volume: 11, Issue:11

    Topics: Administration, Oral; Aged; Aged, 80 and over; Alendronate; Biomarkers; Bone Density; Bone Remodelin

2000

Other Studies

4 other studies available for etidronate and Spinal Diseases

ArticleYear
Gross vertebral collapse associated with long-term disodium etidronate treatment for pelvic Paget's disease.
    Skeletal radiology, 2000, Volume: 29, Issue:5

    Topics: Aged; Alkaline Phosphatase; Anti-Inflammatory Agents; Arthralgia; Diphosphonates; Etidronic Acid; Fo

2000
What causes lower neck uptake in bone scans?
    Radiology, 1977, Volume: 124, Issue:3

    Topics: Adult; Cervical Vertebrae; Diphosphates; Etidronic Acid; Humans; Laryngeal Cartilages; Neoplasm Meta

1977
[Experimental study on the spinal lesions in hyperostotic mouse (twy/twy): special reference to the pathogenesis of the ossification of the spinal ligaments and to the action of ethane-1-hydroxy-1, 1-diphosphonate (EHDP)].
    Nihon Seikeigeka Gakkai zasshi, 1992, Volume: 66, Issue:10

    Topics: Animals; Etidronic Acid; Hyperostosis; Ligaments; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Ossi

1992
[Skeletal scintigraphic findings in spinal diseases].
    Der Radiologe, 1989, Volume: 29, Issue:4

    Topics: Bone and Bones; Diphosphonates; Etidronic Acid; Humans; Organometallic Compounds; Organotechnetium C

1989