Page last updated: 2024-10-26

etidronate and Smear Layer

etidronate has been researched along with Smear Layer in 13 studies

Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.

Smear Layer: Adherent debris produced when cutting the enamel or dentin in cavity preparation. It is about 1 micron thick and its composition reflects the underlying dentin, although different quantities and qualities of smear layer can be produced by the various instrumentation techniques. Its function is presumed to be protective, as it lowers dentin permeability. However, it masks the underlying dentin and interferes with attempts to bond dental material to the dentin.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to examine the smear layer removal capacity of various etidronate treatments."7.91Qualitative analysis of smear layer treated with different etidronate concentrations: A scanning electron microscopy study. ( Emre Erik, C; Maden, M; Onur Orhan, E, 2019)
"To evaluate the effects of ethylenediaminetetraacetic (EDTA), etidronic (EA) and peracetic acid (PA) when used in conjunction with sodium hypochlorite (NaOCl) as root canal irrigants on calcium eluted from canals, smear layer, and root dentine demineralization after instrumentation/irrigation."7.75Effects of ethylenediaminetetraacetic, etidronic and peracetic acid irrigation on human root dentine and the smear layer. ( Gautschi, H; Lottanti, S; Sener, B; Zehnder, M, 2009)
"To evaluate the effects of ethylenediaminetetraacetic (EDTA), etidronic (EA) and peracetic acid (PA) when used in conjunction with sodium hypochlorite (NaOCl) as root canal irrigants on calcium eluted from canals, smear layer, and root dentine demineralization after instrumentation/irrigation."3.75Effects of ethylenediaminetetraacetic, etidronic and peracetic acid irrigation on human root dentine and the smear layer. ( Gautschi, H; Lottanti, S; Sener, B; Zehnder, M, 2009)
"In the present study the smear layer dissolution kinetics of 18% etidronate (HEBP), 9% HEBP, and 17% ethylenediaminetetraacetic acid (EDTA) on human dentin were quantitatively and longitudinally analyzed by using a single-tooth comparative model."3.74Longitudinal co-site optical microscopy study on the chelating ability of etidronate and EDTA using a comparative single-tooth model. ( De-Deus, G; Fidel, RA; Fidel, S; Galan, J; Paciornik, S; Reis, C; Zehnder, M, 2008)
"To test an aqueous gel containing 1-hydroxyethylidene-1, 1-bisphosphonate (HEBP) regarding its interactions with sodium hypochlorite, its calcium binding capacity, and its potential in preventing the formation of a smear layer when used in conjunction with rotary root canal preparation."3.73Assessment of a gel-type chelating preparation containing 1-hydroxyethylidene-1, 1-bisphosphonate. ( Badertscher, M; Girard, S; Paqué, F; Sener, B; Zehnder, M, 2005)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (38.46)29.6817
2010's5 (38.46)24.3611
2020's3 (23.08)2.80

Authors

AuthorsStudies
Aoun, C1
Rechenberg, DK2
Karam, M1
Mhanna, R1
Plotino, G1
Zogheib, C1
Kfir, A1
Goldenberg, C1
Metzger, Z1
Hülsmann, M1
Baxter, S1
Tartari, T1
Borges, MMB1
de Araújo, LBB1
Vivan, RR1
Bonjardim, LR1
Duarte, MAH1
Deari, S1
Mohn, D1
Zehnder, M7
Emre Erik, C1
Onur Orhan, E1
Maden, M1
Morago, A1
Ordinola-Zapata, R1
Ferrer-Luque, CM1
Baca, P1
Ruiz-Linares, M1
Arias-Moliz, MT1
Ulusoy, Öİ1
Zeyrek, S1
Çelik, B1
Lottanti, S1
Gautschi, H1
Sener, B4
Paqué, F2
Schicht, O1
Schmidlin, P2
Girard, S1
Badertscher, M1
Waltimo, T1
De-Deus, G1
Reis, C1
Fidel, S1
Fidel, RA1
Galan, J1
Paciornik, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Using Etidronate in Sodium Hypochlorite Versus Sodium Hypochlorite Irrigating Solution on the Intensity of Postoperative Pain and Bacterial Load Reduction in Patients With Necrotic Pulp: A Randomized Clinical Trial[NCT04035330]34 participants (Anticipated)Interventional2019-09-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for etidronate and Smear Layer

ArticleYear
Reduction of hard-tissue debris accumulation during rotary root canal instrumentation by etidronic acid in a sodium hypochlorite irrigant.
    Journal of endodontics, 2012, Volume: 38, Issue:5

    Topics: Chelating Agents; Dental Pulp Cavity; Dentin; Etidronic Acid; Humans; Image Processing, Computer-Ass

2012

Other Studies

12 other studies available for etidronate and Smear Layer

ArticleYear
Effect of Continuous Chelation Irrigation Using DualRinse HEDP+3% NaOCl with or without High-power Sonic Activation on Debris and Smear Layer Removal.
    European endodontic journal, 2023, Volume: 8, Issue:2

    Topics: Chelating Agents; Edetic Acid; Etidronic Acid; Humans; Root Canal Irrigants; Root Canal Preparation;

2023
Cleanliness and erosion of root canal walls after irrigation with a new HEDP-based solution vs. traditional sodium hypochlorite followed by EDTA. A scanning electron microscope study.
    Clinical oral investigations, 2020, Volume: 24, Issue:10

    Topics: Dental Pulp Cavity; Dentin; Edetic Acid; Etidronic Acid; Humans; Microscopy, Electron, Scanning; Roo

2020
Effects of heat in the properties of NaOCl alone and mixed with etidronate and alkaline tetrasodium EDTA.
    International endodontic journal, 2021, Volume: 54, Issue:4

    Topics: Animals; Cattle; Dental Pulp Cavity; Dentin; Edetic Acid; Etidronic Acid; Hot Temperature; Microscop

2021
Dentine decalcification and smear layer removal by different ethylenediaminetetraacetic acid and 1-hydroxyethane-1,1-diphosphonic acid species.
    International endodontic journal, 2019, Volume: 52, Issue:2

    Topics: Calcium; Chelating Agents; Dentin; Edetic Acid; Etidronic Acid; Humans; Hydrogen-Ion Concentration;

2019
Qualitative analysis of smear layer treated with different etidronate concentrations: A scanning electron microscopy study.
    Microscopy research and technique, 2019, Volume: 82, Issue:9

    Topics: Bicuspid; Dental Pulp Cavity; Etidronic Acid; Humans; Microscopy, Electron, Scanning; Root Canal Irr

2019
Influence of Smear Layer on the Antimicrobial Activity of a Sodium Hypochlorite/Etidronic Acid Irrigating Solution in Infected Dentin.
    Journal of endodontics, 2016, Volume: 42, Issue:11

    Topics: Anti-Infective Agents; Bacteria; Bicuspid; Dental Caries; Dental Pulp Cavity; Dentin; Enterococcus f

2016
Evaluation of smear layer removal and marginal adaptation of root canal sealer after final irrigation using ethylenediaminetetraacetic, peracetic, and etidronic acids with different concentrations.
    Microscopy research and technique, 2017, Volume: 80, Issue:7

    Topics: Dental Pulp Cavity; Dentin; Edetic Acid; Epoxy Resins; Etidronic Acid; Humans; Microscopy, Electron,

2017
Effects of ethylenediaminetetraacetic, etidronic and peracetic acid irrigation on human root dentine and the smear layer.
    International endodontic journal, 2009, Volume: 42, Issue:4

    Topics: Calcium; Decalcification Technique; Dentin; Drug Combinations; Edetic Acid; Etidronic Acid; Humans;

2009
Reducing surface tension in endodontic chelator solutions has no effect on their ability to remove calcium from instrumented root canals.
    Journal of endodontics, 2005, Volume: 31, Issue:8

    Topics: Analysis of Variance; Calcium; Chelating Agents; Citric Acid; Edetic Acid; Etidronic Acid; Humans; P

2005
Assessment of a gel-type chelating preparation containing 1-hydroxyethylidene-1, 1-bisphosphonate.
    International endodontic journal, 2005, Volume: 38, Issue:11

    Topics: Calcium; Chelating Agents; Dental Pulp Cavity; Edetic Acid; Etidronic Acid; Gels; Humans; Materials

2005
Chelation in root canal therapy reconsidered.
    Journal of endodontics, 2005, Volume: 31, Issue:11

    Topics: Anti-Infective Agents, Local; Calcium; Chelating Agents; Chlorine; Citric Acid; Dental Pulp Cavity;

2005
Longitudinal co-site optical microscopy study on the chelating ability of etidronate and EDTA using a comparative single-tooth model.
    Journal of endodontics, 2008, Volume: 34, Issue:1

    Topics: Chelating Agents; Dentin; Edetic Acid; Etidronic Acid; Humans; Longitudinal Studies; Reproducibility

2008