Page last updated: 2024-10-26

etidronate and Recrudescence

etidronate has been researched along with Recrudescence in 24 studies

Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.

Research Excerpts

ExcerptRelevanceReference
"Normocalcemic patients with cancer who had been successfully treated for an episode of hypercalcemia were enrolled in a randomized, multisite, double-blind, placebo-controlled trial designed to determine the efficacy of maintenance oral etidronate in preventing the recurrence of moderate to severe hypercalcemia (serum calcium level, greater than 11."9.06Maintenance etidronate in the prevention of malignancy-associated hypercalcemia. ( Benson, AB; Bockman, RS; Citrin, DL; Greco, FA; Harvey, HA; Rasmussen, P; Schiller, JH; Siris, ES; Stock, JL; Witte, RS, 1987)
"In an open prospective study, we evaluated differences between patients with (wRVF group) and without recurrence of vertebral fracture (woRVF group) during cyclical etidronate therapy for osteoporosis."7.70Recurrence of vertebral fracture with cyclical etidronate therapy in osteoporosis: histomorphometry and X-Ray microanalysis evaluation. ( Alexandre, C; Barou, O; Lafage-Proust, MH; Thomas, T; Vico, L, 1999)
"Although etidronate is effective, risedronate offers a shorter duration of therapy, better and longer-lasting remission, significant reductions in pain, and provides additional remission in subjects who exhibited an incomplete response to previous etidronate treatment."5.09A randomized, double-blind comparison of risedronate and etidronate in the treatment of Paget's disease of bone. Paget's Risedronate/Etidronate Study Group. ( Axelrod, DW; Bekker, PJ; Brown, JP; Hoseyni, MS; Miller, PD; Siris, ES, 1999)
"Normocalcemic patients with cancer who had been successfully treated for an episode of hypercalcemia were enrolled in a randomized, multisite, double-blind, placebo-controlled trial designed to determine the efficacy of maintenance oral etidronate in preventing the recurrence of moderate to severe hypercalcemia (serum calcium level, greater than 11."5.06Maintenance etidronate in the prevention of malignancy-associated hypercalcemia. ( Benson, AB; Bockman, RS; Citrin, DL; Greco, FA; Harvey, HA; Rasmussen, P; Schiller, JH; Siris, ES; Stock, JL; Witte, RS, 1987)
"In an open prospective study, we evaluated differences between patients with (wRVF group) and without recurrence of vertebral fracture (woRVF group) during cyclical etidronate therapy for osteoporosis."3.70Recurrence of vertebral fracture with cyclical etidronate therapy in osteoporosis: histomorphometry and X-Ray microanalysis evaluation. ( Alexandre, C; Barou, O; Lafage-Proust, MH; Thomas, T; Vico, L, 1999)
" Measurement of urinary excretion of EHDP was used to define the best dosage regimen."2.64Biochemical and clinical effects of ethane-1-hydroxy-1,1-diphosphonate in calcium nephrolithiasis. ( Baumann, JM; Bisaz, S; Fleisch, H; Wacker, M, 1978)
"After discontinuation of drug therapy, recurrence was variable but less than expected."2.64Disodium etidronate in the prevention of postoperative recurrence of heterotopic ossification in spinal-cord injury patients. ( Miller, JM; Niemann, KM; Stover, SL, 1976)
"Specific treatment of cancer remains essential to prevent TIH relapse."2.41[Tumor-induced hypercalcemia. Review of bisphosphonate treatment]. ( Lortholary, A, 2001)
"A true recurrence at exactly the same site is quite unusual in algodystrophy."2.40Different patterns of extension and recurrence in algodystrophy. ( Audran, M; Bregeon, C; Legrand, E; Masson, C; Pascaretti, C; Renier, JC, 1998)
"Etidronate treatment at 200 mg/day resulted in the improvement of bone metabolism markers and bone scintigraphy findings."1.32Two cases of monostotic Paget's disease: effects of bisphosphonate. ( Aoki, N; Harada, T; Hoshiro, M; Iwai, H; Miyatake, T; Nishimura, A; Ohno, Y, 2003)
"A case is reported of progressive ossifying myositis (fibrodysplasia ossificans progressiva, Münchmeyer's disease) with onset at 16 years of age by a lesion of internal pterygoid with limitation of opening of mouth."1.27[Permanent constriction of the jaws due to progressive ossifying myositis]. ( Bouvier, R; Delmas, P; Freidel, M; Seguin, P, 1987)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199011 (45.83)18.7374
1990's5 (20.83)18.2507
2000's7 (29.17)29.6817
2010's1 (4.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Seleznev, AN1
Sabilo, ES1
Savin, AA1
Riabov, AG1
Kozlov, SA1
Zima, LN1
Zmievskoĭ, GN1
Conner, GA1
Duffy, M1
Hemmati, I1
Wade, J1
Kelsall, J1
Baranauskaite, A1
Hoshiro, M1
Harada, T1
Iwai, H1
Miyatake, T1
Nishimura, A1
Ohno, Y1
Aoki, N1
Kanis, JA1
Barton, IP1
Johnell, O1
Jacobellis, U1
Salerno, G1
Ruotolo, G1
Baumann, JM2
Biering-Sørensen, F1
Tøndevold, E1
Masson, C1
Audran, M1
Pascaretti, C1
Legrand, E1
Bregeon, C1
Renier, JC1
Thomas, T1
Barou, O1
Vico, L1
Alexandre, C1
Lafage-Proust, MH1
Hosking, DJ1
Miller, PD1
Brown, JP1
Siris, ES2
Hoseyni, MS1
Axelrod, DW1
Bekker, PJ1
Banovac, K1
Lortholary, A1
Bisaz, S1
Fleisch, H1
Wacker, M1
Stover, SL1
Niemann, KM1
Miller, JM1
Ralston, SH1
Gallacher, SJ1
Patel, U1
Dryburgh, FJ1
Fraser, WD1
Cowan, RA1
Boyle, IT1
Ahrengart, L1
Lindgren, U1
Nollen, AJ1
Schiller, JH1
Rasmussen, P1
Benson, AB1
Witte, RS1
Bockman, RS1
Harvey, HA1
Citrin, DL1
Greco, FA1
Stock, JL1
Heath, DA1
Seguin, P1
Delmas, P1
Bouvier, R1
Freidel, M1
Smith, R1
Russell, RG1
Bishop, MC1
Woods, CG1
Bishop, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase I Pilot Trial to Study the Safety and Efficacy of Concomitant Radiotherapy and Zoledronic Acid for the Palliation of Bone Metastases From Breast Cancer, Prostate Cancer and Lung Cancer[NCT00264420]Phase 14 participants (Actual)Interventional2005-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for etidronate and Recrudescence

ArticleYear
Myositis ossificans: a case report of multiple recurrences following third molar extractions and review of the literature.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2009, Volume: 67, Issue:4

    Topics: Adolescent; Diagnosis, Differential; Etidronic Acid; Female; Follow-Up Studies; Humans; Masseter Mus

2009
Risedronate-associated scleritis: a case report and review of the literature.
    Clinical rheumatology, 2012, Volume: 31, Issue:9

    Topics: Adrenal Cortex Hormones; Aged; Brain; China; Diphosphonates; Etidronic Acid; Female; Humans; Inflamm

2012
[Osteoporosis: diagnosis and treatment of vertebral fractures].
    Medicina (Kaunas, Lithuania), 2002, Volume: 38, Issue:8

    Topics: Age Factors; Aged; Calcium; Calcium Channel Blockers; Etidronic Acid; Female; Humans; Male; Middle A

2002
Different patterns of extension and recurrence in algodystrophy.
    Acta orthopaedica Belgica, 1998, Volume: 64, Issue:1

    Topics: Adult; Bone and Bones; Diagnosis, Differential; Disease Progression; Etidronic Acid; Factitious Diso

1998
Prediction and assessment of the response of Paget's disease to bisphosphonate treatment.
    Bone, 1999, Volume: 24, Issue:5 Suppl

    Topics: Alkaline Phosphatase; Bone Resorption; Diphosphonates; Etidronic Acid; Half-Life; Humans; Osteitis D

1999
[Tumor-induced hypercalcemia. Review of bisphosphonate treatment].
    La Revue de medecine interne, 2001, Volume: 22, Issue:7

    Topics: Diagnosis, Differential; Diagnostic Errors; Diphosphonates; Etidronic Acid; Fluid Therapy; Hematolog

2001
Treating Paget's disease.
    British medical journal (Clinical research ed.), 1987, Apr-25, Volume: 294, Issue:6579

    Topics: Calcitonin; Etidronic Acid; Forecasting; Humans; Osteitis Deformans; Recurrence

1987

Trials

7 trials available for etidronate and Recrudescence

ArticleYear
[Mechanisms of formation of chronic low back pain relapse and their correction in patients with dorsopathy].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2008, Volume: 108, Issue:7

    Topics: Algorithms; Anxiety; Bone Density Conservation Agents; Chronic Disease; Depression; Disease Progress

2008
Risedronate decreases fracture risk in patients selected solely on the basis of prior vertebral fracture.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2005, Volume: 16, Issue:5

    Topics: Absorptiometry, Photon; Aged; Anthropometry; Bone Density; Double-Blind Method; Etidronic Acid; Fema

2005
A randomized, double-blind comparison of risedronate and etidronate in the treatment of Paget's disease of bone. Paget's Risedronate/Etidronate Study Group.
    The American journal of medicine, 1999, Volume: 106, Issue:5

    Topics: Administration, Oral; Aged; Alkaline Phosphatase; Bone and Bones; Calcium Channel Blockers; Double-B

1999
Biochemical and clinical effects of ethane-1-hydroxy-1,1-diphosphonate in calcium nephrolithiasis.
    Clinical science and molecular medicine, 1978, Volume: 54, Issue:5

    Topics: Adult; Calcium Phosphates; Calcium Pyrophosphate; Clinical Trials as Topic; Drug Administration Sche

1978
Disodium etidronate in the prevention of postoperative recurrence of heterotopic ossification in spinal-cord injury patients.
    The Journal of bone and joint surgery. American volume, 1976, Volume: 58, Issue:5

    Topics: Adult; Etidronic Acid; Humans; Myositis Ossificans; Organophosphorus Compounds; Postoperative Care;

1976
Comparison of three intravenous bisphosphonates in cancer-associated hypercalcaemia.
    Lancet (London, England), 1989, Nov-18, Volume: 2, Issue:8673

    Topics: Administration, Oral; Bone Resorption; Calcium; Clodronic Acid; Diphosphonates; Drug Administration

1989
Maintenance etidronate in the prevention of malignancy-associated hypercalcemia.
    Archives of internal medicine, 1987, Volume: 147, Issue:5

    Topics: Administration, Oral; Clinical Trials as Topic; Double-Blind Method; Etidronic Acid; Female; Humans;

1987

Other Studies

10 other studies available for etidronate and Recrudescence

ArticleYear
Two cases of monostotic Paget's disease: effects of bisphosphonate.
    Endocrine journal, 2003, Volume: 50, Issue:4

    Topics: Aged; Alendronate; Alkaline Phosphatase; Biomarkers; Bone and Bones; Bone Remodeling; Diphosphonates

2003
[The use of 1-alpha-cholecalciferol in subjects treated for a prolonged time with diphosphonates for recurrent calcium nephrolithiasis].
    Archivos espanoles de urologia, 1984, Volume: 37 Suppl 1

    Topics: Cholecalciferol; Drug Therapy, Combination; Etidronic Acid; Humans; Hypophosphatasia; Kidney Calculi

1984
[Inhibitors of crystallization and calcium nephrolithiasis].
    Therapeutische Umschau. Revue therapeutique, 1980, Volume: 37, Issue:5

    Topics: Calcium Oxalate; Chemical Phenomena; Chemistry; Crystallization; Diphosphates; Etidronic Acid; Glyco

1980
Indomethacin and disodium etidronate for the prevention of recurrence of heterotopic ossification after surgical resection. Two case reports.
    Paraplegia, 1993, Volume: 31, Issue:8

    Topics: Adolescent; Adult; Etidronic Acid; Hip; Humans; Indomethacin; Male; Ossification, Heterotopic; Recur

1993
Recurrence of vertebral fracture with cyclical etidronate therapy in osteoporosis: histomorphometry and X-Ray microanalysis evaluation.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1999, Volume: 14, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Biopsy; Bone Density; Bone Remodeling; Calcium; Electron Probe Micro

1999
The effect of etidronate on late development of heterotopic ossification after spinal cord injury.
    The journal of spinal cord medicine, 2000,Spring, Volume: 23, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Etidronic Acid; Female; Follow-Up Studies; Humans; Infusion

2000
Prevention of ectopic bone formation by local application of ethane-1-hydroxy-1,1-diphosphonate (EHDP): an experimental study in rabbits.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1986, Volume: 4, Issue:1

    Topics: Animals; Bone and Bones; Bone Cements; Bone Neoplasms; Choristoma; Dose-Response Relationship, Drug;

1986
Effects of ethylhydroxydiphosphonate (EHDP) on heterotopic ossification.
    Acta orthopaedica Scandinavica, 1986, Volume: 57, Issue:4

    Topics: Adult; Aged; Drug Evaluation; Elbow Joint; Etidronic Acid; Female; Follow-Up Studies; Hip Joint; Hum

1986
[Permanent constriction of the jaws due to progressive ossifying myositis].
    Revue de stomatologie et de chirurgie maxillo-faciale, 1987, Volume: 88, Issue:3

    Topics: Adolescent; Ankylosis; Chronic Disease; Combined Modality Therapy; Diphosphonates; Etidronic Acid; F

1987
Paget's disease of bone. Experience with a diphosphonate (disodium etidronate) in treatment.
    The Quarterly journal of medicine, 1973, Volume: 42, Issue:166

    Topics: Adult; Aged; Alkaline Phosphatase; Biopsy; Bone Resorption; Calcitonin; Calcium; Clinical Enzyme Tes

1973