Page last updated: 2024-10-26

etidronate and Pregnancy

etidronate has been researched along with Pregnancy in 18 studies

Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"This cross-sectional study assessed geospatial patterns of early-onset hypertensive disorders of pregnancy (eHDP) in primiparous mothers and exposure to industrial emissions using geocoded residential information from Kentucky live (N = 210,804) and still (N = 1,247) birth records (2008-2017) and census block group estimates of aerosol concentrations of arsenic (As), cadmium (Cd), chromium (Cr), lead (Pb), mercury (Hg), selenium (Se), and zinc (Zi) from the Risk Screening Environmental Indicators (RSEI) model."4.12A cross-sectional examination of the early-onset hypertensive disorders of pregnancy and industrial emissions of toxic metals using Kentucky birth records, 2008-2017. ( Browning, SR; Christian, WJ; Kucharska-Newton, A; Walker, CJ, 2022)
"Cows fed a balanced diet with the required amounts of calcium and phosphorus developed acute hypocalcemia and hypophosphatemia shortly after parturition, even in the presence of the a responsive parathyroid gland, when bone resorption was selectively inhibited by the prepartal administration of disodium ethane-1-hydroxy-1, 1-diphosphonate (EHDP)."3.65Experimental parturient hypocalcemia in cows following prepartal chemical inhibition of bone resportion. ( Black, HE; Capen, CC; Geho, WB; Potts, JT; Re, R; Yarrington, JT, 1976)
"Chlorpromazine, which has an antagonistic action towards calmodulin, also suppressed the increases of calcium and ALP in the tooth germ."1.28[In vitro effect of chlorpromazine on the mineralization of tooth germ in mice--comparison with that of retinoic acid and HEBP]. ( Kondo, M, 1991)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19909 (50.00)18.7374
1990's5 (27.78)18.2507
2000's2 (11.11)29.6817
2010's1 (5.56)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Walker, CJ1
Christian, WJ1
Kucharska-Newton, A1
Browning, SR1
Vujasinovic-Stupar, N1
Pejnovic, N1
Markovic, L1
Zlatanovic, M1
Daigo, T1
Krasovskiĭ, GN1
Aĭrapetova, LN1
Reĭzin, BL1
Paterson, CR1
Feely, J1
Richardson, AC1
Tinling, SP1
Chole, RA1
Van Beek, E1
Löwik, C1
Que, I1
Papapoulos, S1
van Beek, ER1
Löwik, CW2
Ebetino, FH1
Papapoulos, SE1
Reinholz, GG1
Getz, B1
Sanders, ES1
Karpeisky, MY1
Padyukova, NSh1
Mikhailov, SN1
Ingle, JN1
Spelsberg, TC1
Yarrington, JT2
Capen, CC2
Black, HE2
Re, R2
Potts, JT2
Geho, WB2
Meradji, M1
de Villeneuve, VH1
Huber, J1
de Bruijn, WC1
Pearse, RG1
Kondo, M1
Stuart, G1
Wren, C1
Bain, H1
Boonekamp, PM1
van de Pluym, G1
van de Wee-Pals, L1
Bloys van Treslong-de Groot, H1
Bijvoet, OL1
Sakiyama, Y3
Tada, I2
Yamamoto, H2
Nakanishi, T1
Yasuda, Y1
Soeda, Y2
Oda, M2
Nagasawa, S1
Ikeo, T2
Takaya, T1
Yamauchi, K1
Miwa, M1
Shioji, I1

Other Studies

18 other studies available for etidronate and Pregnancy

ArticleYear
A cross-sectional examination of the early-onset hypertensive disorders of pregnancy and industrial emissions of toxic metals using Kentucky birth records, 2008-2017.
    PloS one, 2022, Volume: 17, Issue:9

    Topics: Arsenic; Birth Certificates; Cadmium; Chromium; Cross-Sectional Studies; Etidronic Acid; Female; Hea

2022
Pregnancy-associated spinal osteoporosis treated with bisphosphonates: long-term follow-up of maternal and infants outcome.
    Rheumatology international, 2012, Volume: 32, Issue:3

    Topics: Adult; Back Pain; Bone Density; Bone Density Conservation Agents; Child; Diphosphonates; Etidronic A

2012
[Effects of 1-hydroxyethylidene-1,1-bisphosphonate (HEBP) on the formation of dental hard tissue of mouse molar tooth germs in organ culture system].
    Kokubyo Gakkai zasshi. The Journal of the Stomatological Society, Japan, 2003, Volume: 70, Issue:2

    Topics: Amelogenin; Animals; Dental Enamel Proteins; Etidronic Acid; Female; Immunohistochemistry; Mice; Mic

2003
[Toxicological and hygienic evaluation of water content of zinc complexonate of 1-hydroxyethylidene diphosphonic acid with regard to its gonado- and embryotropic effect].
    Gigiena i sanitariia, 1983, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Etidronic Acid; Female; Fetal Death; Male; Mice; Ovary; P

1983
Vitamin D metabolites and analogues, diphosphonates, danazol, and bromocriptine.
    British medical journal (Clinical research ed.), 1983, May-21, Volume: 286, Issue:6378

    Topics: Acromegaly; Bromocriptine; Calcitriol; Danazol; Endometriosis; Etidronic Acid; Female; Fibrocystic B

1983
Risedronate activity in the fetal and neonatal mouse.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1993, Volume: 109, Issue:4

    Topics: Analysis of Variance; Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Culture Techniqu

1993
Dissociation of binding and antiresorptive properties of hydroxybisphosphonates by substitution of the hydroxyl with an amino group.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1996, Volume: 11, Issue:10

    Topics: Amines; Analysis of Variance; Animals; Binding Sites; Bone Matrix; Bone Resorption; Calcium Oxalate;

1996
Binding and antiresorptive properties of heterocycle-containing bisphosphonate analogs: structure-activity relationships.
    Bone, 1998, Volume: 23, Issue:5

    Topics: Alendronate; Animals; Bone and Bones; Bone Resorption; Calcification, Physiologic; Calcium; Culture

1998
Distinct mechanisms of bisphosphonate action between osteoblasts and breast cancer cells: identity of a potent new bisphosphonate analogue.
    Breast cancer research and treatment, 2002, Volume: 71, Issue:3

    Topics: Bone and Bones; Breast Neoplasms; Cell Differentiation; Diphosphonates; Dose-Response Relationship,

2002
Experimental parturient hypocalcemia in cows following prepartal chemical inhibition of bone resportion.
    The American journal of pathology, 1976, Volume: 83, Issue:3

    Topics: Animals; Antigens; Bone Resorption; Calcium; Calcium, Dietary; Cattle; Cattle Diseases; Cyclic AMP;

1976
Effect of ethane-1-hydroxy-1,1-diphosphonate (EHDP) on the ultrastructure of parathyroid glands and plasma immunoreactive parathyroid hormone in pregnant cows fed a low calcium diet.
    Laboratory investigation; a journal of technical methods and pathology, 1977, Volume: 36, Issue:4

    Topics: Animals; Antigens; Calcium; Calcium, Dietary; Cyclic AMP; Duodenum; Etidronic Acid; Female; Homeosta

1977
Idiopathic infantile arterial calcification in siblings: radiologic diagnosis and successful treatment.
    The Journal of pediatrics, 1978, Volume: 92, Issue:3

    Topics: Arteriosclerosis; Calcinosis; Coronary Disease; Etidronic Acid; Female; Humans; Infant, Newborn; Inf

1978
[In vitro effect of chlorpromazine on the mineralization of tooth germ in mice--comparison with that of retinoic acid and HEBP].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 97, Issue:2

    Topics: Alkaline Phosphatase; Animals; Chlorpromazine; Etidronic Acid; Female; Mice; Organ Culture Technique

1991
Idiopathic infantile arterial calcification in two siblings: failure of treatment with diphosphonate.
    British heart journal, 1990, Volume: 64, Issue:2

    Topics: Calcinosis; Consanguinity; Echocardiography; Etidronic Acid; Female; Fetal Diseases; Humans; Infant,

1990
Bisphosphonates can reduce osteoclastic bone resorption by two different mechanisms.
    Advances in experimental medicine and biology, 1986, Volume: 208

    Topics: Animals; Bone and Bones; Bone Resorption; Cell Differentiation; Chemotaxis; Clodronic Acid; Culture

1986
The effect of ethane-1-hydroxy-1,1-diphosphonate (EHDP) on fetal mice during pregnancy--with emphasis on implantation and fetal weight.
    Journal of Osaka Dental University, 1986, Volume: 19, Issue:2

    Topics: Animals; Body Weight; Embryo Implantation; Etidronic Acid; Female; Fetal Viability; Fetus; Male; Mic

1986
The effect of ethane-1-hydroxy-1, 1-diphosphonate (EHDP) on fetal mice during pregnancy. Part 2. External anomalies.
    Journal of Osaka Dental University, 1986, Volume: 20, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Brain; Cleft Lip; Cleft Palate; Etidronic Acid; Face; Female;

1986
Effect of ethane-1-hdryoxy-1, 1-diphosphonate (EHDP) on fetal mice during pregnancy. Chemical changes in skin collagen.
    Journal of Osaka Dental University, 1987, Volume: 21, Issue:2

    Topics: Animals; Collagen; Etidronic Acid; Female; Fetus; Mice; Pregnancy; Skin; Solubility

1987