etidronate has been researched along with Pain, Intractable in 18 studies
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
Pain, Intractable: Persistent pain that is refractory to some or all forms of treatment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate the efficacy of 186Re-1,1-hydroxyethylidene diphosphonate (etidronate) in breast cancer patients with painful bone metastases." | 9.09 | 186Re-etidronate in breast cancer patients with metastatic bone pain. ( Blijham, GH; de Klerk, JM; Han, SH; Quirijnen, JM; van Dijk, A; van het Schip, AD; van Rijk, PP; Zonneberg, BA, 1999) |
| "The aim of this study was to evaluate the efficacy of 186Re-1,1-hydroxyethylidene diphosphonate (etidronate) in breast cancer patients with painful bone metastases." | 5.09 | 186Re-etidronate in breast cancer patients with metastatic bone pain. ( Blijham, GH; de Klerk, JM; Han, SH; Quirijnen, JM; van Dijk, A; van het Schip, AD; van Rijk, PP; Zonneberg, BA, 1999) |
| "It is concluded that in prostate cancer patients, the maximum tolerated dose of 188Re-HEDP is 3." | 2.69 | Dose escalation study with rhenium-188 hydroxyethylidene diphosphonate in prostate cancer patients with osseous metastases. ( Bender, H; Biersack, HJ; Grünwald, F; Guhlke, S; Knapp, FF; Palmedo, H; Risse, J; Sartor, J; Schoeneich, G, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (16.67) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 10 (55.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Silberstein, EB | 2 |
| Taylor, AT | 1 |
| Palmedo, H | 2 |
| Manka-Waluch, A | 1 |
| Albers, P | 1 |
| Schmidt-Wolf, IG | 1 |
| Reinhardt, M | 1 |
| Ezziddin, S | 1 |
| Joe, A | 1 |
| Roedel, R | 1 |
| Fimmers, R | 1 |
| Knapp, FF | 2 |
| Guhlke, S | 2 |
| Biersack, HJ | 2 |
| Koutsikos, J | 1 |
| Leondi, A | 1 |
| McEwan, AJ | 1 |
| Lewington, VJ | 1 |
| Han, SH | 2 |
| Zonneberg, BA | 1 |
| de Klerk, JM | 2 |
| Quirijnen, JM | 1 |
| van het Schip, AD | 1 |
| van Dijk, A | 1 |
| Blijham, GH | 1 |
| van Rijk, PP | 2 |
| Giannakenas, C | 1 |
| Kalofonos, HP | 1 |
| Apostolopoulos, DJ | 1 |
| Zarakovitis, J | 1 |
| Kosmas, C | 1 |
| Vassilakos, PJ | 1 |
| Bender, H | 1 |
| Sartor, J | 1 |
| Schoeneich, G | 1 |
| Risse, J | 1 |
| Grünwald, F | 1 |
| Sciuto, R | 2 |
| Tofani, A | 1 |
| Festa, A | 2 |
| Giannarelli, D | 1 |
| Pasqualoni, R | 2 |
| Maini, CL | 2 |
| Siberstein, EB | 1 |
| Semprebene, A | 1 |
| Rea, S | 1 |
| Bergomi, S | 1 |
| Piffanelli, A | 1 |
| Dafermou, A | 1 |
| Giganti, M | 1 |
| Colamussi, P | 1 |
| Pizzocaro, C | 1 |
| Bestagno, M | 1 |
| Zonnenberg, BA | 1 |
| Tan, S | 1 |
| Englaro, EE | 2 |
| Schroder, LE | 2 |
| Thomas, SR | 2 |
| Williams, CC | 2 |
| Maxon, HR | 2 |
| Hertzberg, VS | 1 |
| Samaratunga, R | 1 |
| Smith, H | 1 |
| Moulton, JS | 1 |
| Ehrhardt, GJ | 1 |
| Carey, PO | 1 |
| Lippert, MC | 1 |
| Kawamura, J | 1 |
| Tochigi, H | 1 |
| Yanagawa, M | 1 |
| Yoshida, O | 1 |
| Hida, S | 1 |
| Mori, O | 1 |
| Suzuki, N | 1 |
| Saito, K | 1 |
| Komatsu, Y | 1 |
| Hatayama, T | 1 |
| Williams, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Repeated Rhenium-188-HEDP Versus Radium-223-chloride in Patients With Metastatic Castration-resistant Prostate Cancer: The RaRe Study[NCT03458559] | Phase 3 | 402 participants (Anticipated) | Interventional | 2018-05-16 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for etidronate and Pain, Intractable
| Article | Year |
|---|---|
Targeted radionuclide therapy for bone metastases.
Topics: Analgesics; Bone Neoplasms; Combined Modality Therapy; Etidronic Acid; Humans; Organometallic Compou | 1993 |
186Re-etidronate. Efficacy of palliative radionuclide therapy for painful bone metastases.
Topics: Bone Neoplasms; Etidronic Acid; Female; Humans; Male; Organometallic Compounds; Pain, Intractable; P | 2001 |
8 trials available for etidronate and Pain, Intractable
| Article | Year |
|---|---|
Repeated bone-targeted therapy for hormone-refractory prostate carcinoma: tandomized phase II trial with the new, high-energy radiopharmaceutical rhenium-188 hydroxyethylidenediphosphonate.
Topics: Aged; Bone Neoplasms; Disease Progression; Dose-Response Relationship, Radiation; Etidronic Acid; Hu | 2003 |
186Re-etidronate in breast cancer patients with metastatic bone pain.
Topics: Bone Neoplasms; Breast Neoplasms; Etidronic Acid; Female; Humans; Organometallic Compounds; Pain, In | 1999 |
Preliminary results of the use of Re-186-HEDP for palliation of pain in patients with metastatic bone disease.
Topics: Adult; Aged; Aged, 80 and over; Bone Neoplasms; Breast Neoplasms; Etidronic Acid; Female; Humans; Ma | 2000 |
Dose escalation study with rhenium-188 hydroxyethylidene diphosphonate in prostate cancer patients with osseous metastases.
Topics: Bone Neoplasms; Dose-Response Relationship, Radiation; Etidronic Acid; Humans; Male; Pain Measuremen | 2000 |
Metastatic bone pain palliation with 89-Sr and 186-Re-HEDP in breast cancer patients.
Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Disease-Free Survival; Etidronic Acid; Female; Humans | 2001 |
Radionuclide therapy for painful bone metastases. An Italian multicentre observational study. Writing Committee of an Ad Hoc Study Group.
Topics: Bone Neoplasms; Etidronic Acid; Humans; Male; Organometallic Compounds; Pain, Intractable; Palliativ | 2001 |
Rhenium-186(Sn)HEDP for treatment of painful osseous metastases: results of a double-blind crossover comparison with placebo.
Topics: Aged; Bone Neoplasms; Double-Blind Method; Etidronic Acid; Female; Humans; Male; Organometallic Comp | 1991 |
Strontium-89 therapy for the pain of osseous metastases.
Topics: Bone Neoplasms; Clinical Trials as Topic; Dose-Response Relationship, Radiation; Etidronic Acid; Fem | 1985 |
8 other studies available for etidronate and Pain, Intractable
| Article | Year |
|---|---|
EANM procedure guidelines for treatment of refractory metastatic bone pain.
Topics: Bone Neoplasms; Etidronic Acid; Europe; Humans; Nuclear Medicine; Organometallic Compounds; Organoph | 2003 |
Re-186 HEDP treatment in breast cancer patients with bone metastases.
Topics: Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Combined Modality Therapy; Dipho | 2008 |
Pain palliation and nuclear medicine.
Topics: Bone Neoplasms; Etidronic Acid; Humans; Organometallic Compounds; Organophosphorus Compounds; Pain, | 1993 |
Short- and long-term effects of 186Re-1,1-hydroxyethylidene diphosphonate in the treatment of painful bone metastases.
Topics: Aged; Bone Neoplasms; Breast Neoplasms; Etidronic Acid; Female; Follow-Up Studies; Humans; Male; Org | 2000 |
Advances in our understanding of the treatment of painful bone metastasis.
Topics: Bone Neoplasms; Breast Neoplasms; Etidronic Acid; Female; Humans; Male; Organometallic Compounds; Pa | 2000 |
Safety and efficacy of repeated sequential administrations of Re-186(Sn)HEDP as palliative therapy for painful skeletal metastases. Initial case reports of two patients.
Topics: Adenocarcinoma; Aged; Bone Neoplasms; Etidronic Acid; Humans; Male; Organometallic Compounds; Pain, | 1992 |
Treatment of painful prostatic bone metastases with oral etidronate disodium.
Topics: Administration, Oral; Bone Neoplasms; Etidronic Acid; Humans; Male; Orchiectomy; Pain Measurement; P | 1988 |
[Effects of etidronate disodium (EHDP) on urogenital malignancies with bone metastasis: a multicentered collaborative evaluation].
Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Bone and Bones; Bone Neoplasms; Calcium; Drug Evaluat | 1988 |