etidronate has been researched along with Osteolysis in 30 studies
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
Osteolysis: Dissolution of bone that particularly involves the removal or loss of calcium.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We conclude that EHDP therapy used in this dosage schedule does not have a clinically significant impact in multiple myeloma." | 6.67 | Effect of daily etidronate on the osteolysis of multiple myeloma. ( Belch, AR; Bergsagel, DE; Johnston, D; O'Reilly, S; Pater, J; Sutton, D; Wilson, J; Wilson, K; Zee, B, 1991) |
| "Control of Paget's disease of bone has been possible through treatment with agents that decrease bone resorption; calcitonins, diphosphonates, and mithramycin." | 3.75 | Etidronate disodium in the treatment of Paget's disease of bone. ( Krane, SM, 1982) |
| " We conclude that EHDP therapy used in this dosage schedule does not have a clinically significant impact in multiple myeloma." | 2.67 | Effect of daily etidronate on the osteolysis of multiple myeloma. ( Belch, AR; Bergsagel, DE; Johnston, D; O'Reilly, S; Pater, J; Sutton, D; Wilson, J; Wilson, K; Zee, B, 1991) |
| "This is particularly true in multiple myeloma (MM), where bone involvement markedly influences the quality of life of patients." | 2.40 | The role of bisphosphonates for the treatment of bone disease in multiple myeloma. ( Musto, P, 1998) |
| "Haematologic malignancies and solid tumors are often complicated by the bone tissue destruction." | 2.39 | [Pharmacologic therapy of bone tissue changes due to hematologic malignancies and bone metastasis]. ( Kiełbiński, M, 1994) |
| "This osteolysis was evaluated by measuring the increased area of bone resorption in reduced opacity to radiograph and histologic study." | 1.28 | Inhibition by a new bisphosphonate (AHBuBP) of bone resorption induced by the MBT-2 tumor of mice. ( Koiso, K; Miyagawa, I; Nemoto, R; Satou, S, 1991) |
| "sarcoma 180 was in fact related to alterations of osseous tissues by EHDP." | 1.27 | Effects of disodium etidronate in murine tumor models. ( Coccioli, G; Corti, F; Donelli, MG; Filippeschi, S; Garattini, S; Guaitani, A; Italia, C; Mantovani, A; Marmonti, L; Polentarutti, N, 1984) |
| "Etidronate was also found to prevent bone metastasis in syngeneic rat mammary carcinoma." | 1.27 | Effect of etidronate disodium on the interactions between malignancy and bone. ( Garattini, S; Guaitani, A; Mantovani, A, 1987) |
| "This osteolysis was evaluated by measuring the increased area of bone resorption by its reduced opacity to X-ray, and histology." | 1.27 | Establishment of a model to evaluate inhibition of bone resorption induced by human prostate cancer cells in nude mice. ( Harada, M; Kanoh, S; Koiso, K; Nemoto, R, 1988) |
| "Osteolysis is estimated by the amount of 45Ca released from bone to medium, the mice being given injections of 45Ca on their day of birth." | 1.26 | Inhibition by two diphosphonates of bone lysis in tumor-conditioned media. ( Barras, C; Baud, M; Courvoisier, B; Jung, A; Mermillod, B, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (46.67) | 18.7374 |
| 1990's | 13 (43.33) | 18.2507 |
| 2000's | 1 (3.33) | 29.6817 |
| 2010's | 2 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamada, H | 1 |
| Matsuo, A | 1 |
| Koizumi, T | 1 |
| Satomi, T | 1 |
| Chikazu, D | 1 |
| Hoppé, E | 1 |
| Masson, C | 1 |
| Laffitte, A | 1 |
| Chappard, D | 1 |
| Audran, M | 1 |
| Kamizono, J | 1 |
| Okada, Y | 1 |
| Shirahata, A | 1 |
| Tanaka, Y | 1 |
| Krane, SM | 1 |
| Rondier, J | 1 |
| Huchet, B | 1 |
| Cayla, J | 1 |
| Guaitani, A | 2 |
| Polentarutti, N | 1 |
| Filippeschi, S | 1 |
| Marmonti, L | 1 |
| Corti, F | 1 |
| Italia, C | 1 |
| Coccioli, G | 1 |
| Donelli, MG | 1 |
| Mantovani, A | 2 |
| Garattini, S | 2 |
| Anderson, C | 1 |
| Cape, RD | 1 |
| Crilly, RG | 1 |
| Hodsman, AB | 1 |
| Wolfe, BM | 1 |
| Raisz, LG | 1 |
| Jung, A | 2 |
| Mermillod, B | 2 |
| Barras, C | 2 |
| Baud, M | 1 |
| Courvoisier, B | 2 |
| Kiełbiński, M | 1 |
| Pandey, R | 1 |
| Quinn, JM | 1 |
| Sabokbar, A | 1 |
| Athanasou, NA | 1 |
| Marin, F | 1 |
| Billey, T | 1 |
| Lassoued, S | 1 |
| Body, JJ | 2 |
| Coleman, RE | 1 |
| Piccart, M | 1 |
| Van Gelder, JM | 1 |
| Breuer, E | 1 |
| Schlossman, A | 1 |
| Ornoy, A | 1 |
| Mönkkönen, J | 1 |
| Similä, J | 1 |
| Klenner, T | 1 |
| Stadler, H | 1 |
| Krempien, B | 1 |
| Patlas, N | 1 |
| Golomb, G | 1 |
| Zander, DR | 1 |
| Lander, P | 1 |
| Bégin, LR | 1 |
| Hadjipavlou, AG | 1 |
| Musto, P | 1 |
| Lombardi, A | 1 |
| Mundy, GR | 1 |
| Belch, AR | 1 |
| Bergsagel, DE | 1 |
| Wilson, K | 1 |
| O'Reilly, S | 1 |
| Wilson, J | 1 |
| Sutton, D | 1 |
| Pater, J | 1 |
| Johnston, D | 1 |
| Zee, B | 1 |
| Nemoto, R | 4 |
| Satou, S | 2 |
| Miyagawa, I | 1 |
| Koiso, K | 4 |
| Sato, S | 1 |
| Nishijima, Y | 1 |
| Miyakawa, I | 1 |
| Harada, M | 2 |
| Fedou, P | 1 |
| Codine, P | 1 |
| Simon, L | 1 |
| Uchida, K | 1 |
| Tsutsumi, M | 1 |
| Satou, T | 1 |
| Kawamura, J | 1 |
| Tochigi, H | 1 |
| Yanagawa, M | 1 |
| Yoshida, O | 1 |
| Hida, S | 1 |
| Mori, O | 1 |
| Suzuki, N | 1 |
| Saito, K | 1 |
| Komatsu, Y | 1 |
| Hatayama, T | 1 |
| Kanoh, S | 1 |
| Wendling, D | 1 |
| Guidet, M | 1 |
| Fleisch, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I Pilot Trial to Study the Safety and Efficacy of Concomitant Radiotherapy and Zoledronic Acid for the Palliation of Bone Metastases From Breast Cancer, Prostate Cancer and Lung Cancer[NCT00264420] | Phase 1 | 4 participants (Actual) | Interventional | 2005-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for etidronate and Osteolysis
| Article | Year |
|---|---|
Etidronate disodium in the treatment of Paget's disease of bone.
Topics: Bone Resorption; Calcitonin; Clinical Trials as Topic; Diphosphates; Drug Evaluation; Etidronic Acid | 1982 |
[Pharmacologic therapy of bone tissue changes due to hematologic malignancies and bone metastasis].
Topics: Bone Neoplasms; Calcitonin; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Neoplasms; Osteo | 1994 |
Use of bisphosphonates in cancer patients.
Topics: Alendronate; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Clodronic Acid; Diphosphonates; Etid | 1996 |
The role of bisphosphonates for the treatment of bone disease in multiple myeloma.
Topics: Adult; Aged; Aged, 80 and over; Bone Remodeling; Clinical Trials as Topic; Clodronic Acid; Diphospho | 1998 |
Bisphosphonates as cancer drugs.
Topics: Antineoplastic Agents; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Neoplasm Proteins; Ne | 1999 |
Bone metastases and tumor-induced hypercalcemia.
Topics: Antineoplastic Agents; Bone Neoplasms; Bone Resorption; Calcitonin; Combined Modality Therapy; Dipho | 1992 |
[Biphosphonate as a therapeutic drug--experimental studies and clinical application].
Topics: Animals; Calcinosis; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hypercalcemia; Hyperpar | 1985 |
3 trials available for etidronate and Osteolysis
| Article | Year |
|---|---|
Etidronate disodium in the treatment of Paget's disease of bone.
Topics: Bone Resorption; Calcitonin; Clinical Trials as Topic; Diphosphates; Drug Evaluation; Etidronic Acid | 1982 |
Treatment of Paget's disease of bone with alendronate.
Topics: Adult; Aged; Aged, 80 and over; Alendronate; Alkaline Phosphatase; Bone Resorption; Etidronic Acid; | 1999 |
Effect of daily etidronate on the osteolysis of multiple myeloma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Body Height; Cyclophosphamide; Dexa | 1991 |
21 other studies available for etidronate and Osteolysis
| Article | Year |
|---|---|
A simple evaluation method for early detection of bisphosphonate-related osteonecrosis of the mandible using computed tomography.
Topics: Administration, Intravenous; Administration, Oral; Alendronate; Alveolar Process; Bisphosphonate-Ass | 2014 |
Osteomalacia in a patient with Paget's bone disease treated with long-term etidronate.
Topics: Aged, 80 and over; Alkaline Phosphatase; Biopsy; Bone Density Conservation Agents; Calcification, Ph | 2012 |
Bisphosphonate induces remission of refractory osteolysis in langerhans cell histiocytosis.
Topics: Bone Resorption; Diphosphonates; Etidronic Acid; Female; Histiocytosis, Langerhans-Cell; Humans; Inf | 2002 |
[Pseudosarcomatous osteolysis in a Paget's disease patient treated with disodium etidronate (EHDP)].
Topics: Bone Neoplasms; Bone Resorption; Calcitonin; Diagnosis, Differential; Etidronic Acid; Humans; Male; | 1984 |
Effects of disodium etidronate in murine tumor models.
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Carcinoma 256, Walker; Etidronic Acid; Hypercalcemia | 1984 |
Preliminary observations of a form of coherence therapy for osteoporosis.
Topics: Aged; Biopsy; Bone and Bones; Drug Evaluation; Drug Therapy, Combination; Etidronic Acid; Female; Hu | 1984 |
New diphosphonates to block bone resorption.
Topics: Animals; Bone Resorption; Breast Neoplasms; Clodronic Acid; Diphosphonates; Double-Blind Method; Eti | 1980 |
Inhibition by two diphosphonates of bone lysis in tumor-conditioned media.
Topics: Animals; Bone Resorption; Clodronic Acid; Culture Media; Diphosphonates; Etidronic Acid; Indomethaci | 1981 |
Bisphosphonate inhibition of bone resorption induced by particulate biomaterial-associated macrophages.
Topics: Animals; Biocompatible Materials; Bone and Bones; Cells, Cultured; Dose-Response Relationship, Drug; | 1996 |
[Pseudosarcomatous osteolysis of the femur in a patient with Paget's bone disease treated with long-term etidronate disodium: apropos of a new case].
Topics: Aged; Etidronic Acid; Femur; Humans; Male; Osteitis Deformans; Osteolysis; Time Factors | 1996 |
In vitro and in vivo effects of tetrakisphosphonates on bone resorption, tumor osteolysis, ectopic calcification, and macrophages.
Topics: Animals; Bioprosthesis; Bone Resorption; Calcinosis; Carcinoma 256, Walker; Cell Line; Cell Survival | 1997 |
Focal osteolysis as a complication of therapy for Paget's disease: case report.
Topics: Acetabulum; Antibiotics, Antineoplastic; Arthroplasty, Replacement, Hip; Bone Remodeling; Calcitonin | 1998 |
[Effect of 2 phosphonates on the osteolysis induced by tumor extracts].
Topics: Animals; Animals, Newborn; Clodronic Acid; Diphosphonates; Etidronic Acid; Mice; Neoplasm Metastasis | 1979 |
Inhibition by a new bisphosphonate (AHBuBP) of bone resorption induced by the MBT-2 tumor of mice.
Topics: Alendronate; Animals; Diphosphonates; Etidronic Acid; Female; Mice; Mice, Inbred C3H; Necrosis; Neop | 1991 |
Effects of a new bisphosphonate (AHBuBP) on osteolysis induced by human prostate cancer cells in nude mice.
Topics: Adenocarcinoma; Alendronate; Animals; Diphosphonates; Etidronic Acid; Humans; Male; Mice; Mice, Nude | 1990 |
[Pseudotumoral osteolysis caused by diphosphonates].
Topics: Bone Resorption; Etidronic Acid; Female; Humans; Middle Aged; Osteitis Deformans; Osteolysis; Radiog | 1986 |
Effect of etidronate disodium on the interactions between malignancy and bone.
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Etidronic Acid; Hypercalcemia; Mice; Osteolysis; Par | 1987 |
A model of localized osteolysis induced by the MBT-2 tumor in mice and its responsiveness to etidronate disodium.
Topics: Animals; Bone Neoplasms; Bone Resorption; Etidronic Acid; Mice; Neoplasm Transplantation; Neoplasms, | 1987 |
[Effects of etidronate disodium (EHDP) on urogenital malignancies with bone metastasis: a multicentered collaborative evaluation].
Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Bone and Bones; Bone Neoplasms; Calcium; Drug Evaluat | 1988 |
Establishment of a model to evaluate inhibition of bone resorption induced by human prostate cancer cells in nude mice.
Topics: Adenocarcinoma; Animals; Bone Neoplasms; Cell Line; Etidronic Acid; Male; Mice; Neoplasm Invasivenes | 1988 |
Osteolytic Paget's disease of bone under unduly etidronate therapy.
Topics: Aged; Etidronic Acid; Humans; Male; Osteitis Deformans; Osteolysis | 1988 |