etidronate has been researched along with Osteoarthritis in 18 studies
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Osteoarthritis was surgically induced on one knee of 32 New Zealand White rabbits using the contralateral as healthy controls." | 5.40 | Effects of glucosamine and risedronate alone or in combination in an experimental rabbit model of osteoarthritis. ( Caeiro, JR; González-Cantalapiedra, A; Guede, D; López-Peña, M; Muñoz, F; Permuy, M, 2014) |
| "Cohort study in a tertiary care university affiliated hospital in corticosteroid treated patients, with polymyalgia rheumatica, asthma, systemic lupus erythematosus, rheumatoid arthritis, or temporal arteritis, examining the effects of ICT etidronate." | 5.07 | Intermittent cyclic therapy with etidronate in the prevention of corticosteroid induced bone loss. ( Adachi, J; Bensen, WG; Bianchi, F; Cividino, A; Craig, GL; Cranney, A; Goldsmith, CH; Kaminska, E; Papaioannou, A; Sebaldt, RJ, 1994) |
| " The patients received an oral dosage of about 20 mg/kg body weight the first 2 months and about 5 mg/kg from month 3-6." | 2.66 | [Therapy of psoriatic osteoarthropathy with EHDP]. ( Altmeyer, P; Holzmann, H; Hör, G; Maul, FD; Thiers, G, 1985) |
| "Osteoarthritis was surgically induced on one knee of 32 New Zealand White rabbits using the contralateral as healthy controls." | 1.40 | Effects of glucosamine and risedronate alone or in combination in an experimental rabbit model of osteoarthritis. ( Caeiro, JR; González-Cantalapiedra, A; Guede, D; López-Peña, M; Muñoz, F; Permuy, M, 2014) |
| " In two groups, anterior cruciate ligament transection was performed and half were left untreated, and the other half dosed with risedronate (0." | 1.35 | Preservation of periarticular cancellous morphology and mechanical stiffness in post-traumatic experimental osteoarthritis by antiresorptive therapy. ( Boyd, SK; Doschak, MR; MacNeil, JA; Zernicke, RF, 2008) |
| " We surgically transected the anterior cruciate ligament (ACLX) in two groups of rabbits; the first group was dosed with BP (risedronate, 0." | 1.32 | Antiresorptive therapy conserves some periarticular bone and ligament mechanical properties after anterior cruciate ligament disruption in the rabbit knee. ( Bray, RC; Doschak, MR; Hanley, DA; Wohl, GR; Zernicke, RF, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (44.44) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thomsen, JS | 1 |
| Straarup, TS | 1 |
| Danielsen, CC | 1 |
| Oxlund, H | 1 |
| Brüel, A | 1 |
| Permuy, M | 1 |
| Guede, D | 1 |
| López-Peña, M | 1 |
| Muñoz, F | 1 |
| González-Cantalapiedra, A | 1 |
| Caeiro, JR | 1 |
| Bruyère, O | 1 |
| Burlet, N | 1 |
| Delmas, PD | 1 |
| Rizzoli, R | 1 |
| Cooper, C | 1 |
| Reginster, JY | 1 |
| Yemisci, OU | 1 |
| Yalbuzdag, SA | 1 |
| Karatas, M | 1 |
| Doschak, MR | 2 |
| Wohl, GR | 1 |
| Hanley, DA | 1 |
| Bray, RC | 1 |
| Zernicke, RF | 2 |
| Felson, DT | 1 |
| Kim, YJ | 1 |
| MacNeil, JA | 1 |
| Boyd, SK | 1 |
| Kawasaki, T | 1 |
| Kurosawa, H | 1 |
| Ikeda, H | 1 |
| Kim, SG | 1 |
| Osawa, A | 1 |
| Takazawa, Y | 1 |
| Kubota, M | 1 |
| Ishijima, M | 1 |
| Halverson, PB | 2 |
| Cheung, HS | 1 |
| McCarty, DJ | 2 |
| Adachi, J | 1 |
| Cranney, A | 1 |
| Goldsmith, CH | 1 |
| Bensen, WG | 1 |
| Bianchi, F | 1 |
| Cividino, A | 1 |
| Craig, GL | 1 |
| Kaminska, E | 1 |
| Sebaldt, RJ | 1 |
| Papaioannou, A | 1 |
| Doyle, DV | 1 |
| Dunn, CJ | 1 |
| Willoughby, DA | 1 |
| Oppenheim, BE | 1 |
| Cantez, S | 1 |
| Forys, VA | 1 |
| Altman, RD | 1 |
| Brown, M | 1 |
| Gargano, F | 1 |
| Thomas, BJ | 1 |
| Amstutz, HC | 1 |
| Holzmann, H | 1 |
| Thiers, G | 1 |
| Altmeyer, P | 1 |
| Maul, FD | 1 |
| Hör, G | 1 |
| Bijvoet, OL | 1 |
| Nollen, AJ | 1 |
| Slooff, TJ | 1 |
| Feith, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Placebo Controlled Trial Testing The Effect of Zoledronic Acid on Hip Osteoarthritis[NCT04303026] | Phase 3 | 70 participants (Anticipated) | Interventional | 2020-03-02 | Recruiting | ||
| Pilot, Open Non-controled Trial to Assess the Feasibility of Implementing Objective Parameters as Primary Endpoints in a Clinical Trial With Patients Affected by Knee Osteoarthritis[NCT03421054] | 8 participants (Actual) | Interventional | 2018-03-19 | Completed | |||
| Double Blind, Placebo Controlled Trial to Evaluate the Effects of a Nutraceutical Containing High-Molecular-Weight Hyaluronic Acid (HA) and Acetyl-11-Keto-Beta-Boswellic Acid (AKBA) in Patients Affected by Knee Osteoarthritis[NCT03612986] | 72 participants (Actual) | Interventional | 2018-08-22 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for etidronate and Osteoarthritis
| Article | Year |
|---|---|
Evaluation of symptomatic slow-acting drugs in osteoarthritis using the GRADE system.
Topics: Anthraquinones; Antirheumatic Agents; Calcitonin; Chondroitin Sulfates; Clinical Trials as Topic; Et | 2008 |
Evaluation of symptomatic slow-acting drugs in osteoarthritis using the GRADE system.
Topics: Anthraquinones; Antirheumatic Agents; Calcitonin; Chondroitin Sulfates; Clinical Trials as Topic; Et | 2008 |
Evaluation of symptomatic slow-acting drugs in osteoarthritis using the GRADE system.
Topics: Anthraquinones; Antirheumatic Agents; Calcitonin; Chondroitin Sulfates; Clinical Trials as Topic; Et | 2008 |
Evaluation of symptomatic slow-acting drugs in osteoarthritis using the GRADE system.
Topics: Anthraquinones; Antirheumatic Agents; Calcitonin; Chondroitin Sulfates; Clinical Trials as Topic; Et | 2008 |
The futility of current approaches to chondroprotection.
Topics: Anti-Bacterial Agents; Bone Density Conservation Agents; Cartilage, Articular; Chondrocytes; Doxycyc | 2007 |
4 trials available for etidronate and Osteoarthritis
| Article | Year |
|---|---|
Additive effects of glucosamine or risedronate for the treatment of osteoarthritis of the knee combined with home exercise: a prospective randomized 18-month trial.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Bone Density Conservation Agents; | 2008 |
Intermittent cyclic therapy with etidronate in the prevention of corticosteroid induced bone loss.
Topics: Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Bone Density; Cohort Studies; Dose-Resp | 1994 |
Prevention of heterotopic bone formation: clinical experience with diphosphonates.
Topics: Clinical Trials as Topic; Etidronic Acid; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; M | 1987 |
[Therapy of psoriatic osteoarthropathy with EHDP].
Topics: Administration, Oral; Adult; Aged; Clinical Trials as Topic; Etidronic Acid; Female; Humans; Male; M | 1985 |
12 other studies available for etidronate and Osteoarthritis
| Article | Year |
|---|---|
No effect of risedronate on articular cartilage damage in the Dunkin Hartley guinea pig model of osteoarthritis.
Topics: Animals; Bone Density Conservation Agents; Bone Resorption; Calcification, Physiologic; Cartilage, A | 2013 |
Effects of glucosamine and risedronate alone or in combination in an experimental rabbit model of osteoarthritis.
Topics: Animals; Bone Density Conservation Agents; Etidronic Acid; Female; Glucosamine; Humans; Osteoarthrit | 2014 |
Risedronate-induced arthritis.
Topics: Bone Density Conservation Agents; Etidronic Acid; Female; Humans; Middle Aged; Osteoarthritis; Osteo | 2010 |
Antiresorptive therapy conserves some periarticular bone and ligament mechanical properties after anterior cruciate ligament disruption in the rabbit knee.
Topics: Animals; Anterior Cruciate Ligament; Biomechanical Phenomena; Bone Density; Etidronic Acid; Osteoart | 2004 |
Preservation of periarticular cancellous morphology and mechanical stiffness in post-traumatic experimental osteoarthritis by antiresorptive therapy.
Topics: Animals; Bone Density Conservation Agents; Bone Resorption; Computer Simulation; Disease Models, Ani | 2008 |
Enzymatic release of microspheroids containing hydroxyapatite crystals from synovium and of calcium pyrophosphate dihydrate crystals from cartilage.
Topics: Calcium Pyrophosphate; Cartilage, Articular; Diphosphates; Etidronic Acid; Humans; Hydroxyapatites; | 1982 |
Identification of hydroxyapatite crystals in synovial fluid.
Topics: Adult; Aged; Arthritis, Juvenile; Arthritis, Rheumatoid; Chondrocalcinosis; Etidronic Acid; Female; | 1979 |
Potassium permanganate induced calcergy: a model to study the effects of drugs on hydroxyapatite crystal deposition.
Topics: Animals; Calcinosis; Clodronic Acid; Dexamethasone; Disease Models, Animal; Etidronic Acid; Hydroxya | 1979 |
What causes lower neck uptake in bone scans?
Topics: Adult; Cervical Vertebrae; Diphosphates; Etidronic Acid; Humans; Laryngeal Cartilages; Neoplasm Meta | 1977 |
Etidronate and osteoarthritis.
Topics: Drug Administration Schedule; Etidronic Acid; Female; Humans; Osteoarthritis; Osteoporosis, Postmeno | 1991 |
Low back pain in Paget's disease of bone.
Topics: Back Pain; Diagnosis, Differential; Etidronic Acid; Humans; Osteitis Deformans; Osteoarthritis; Radi | 1987 |
Effect of a diphosphonate on para-articular ossification after total hip replacement.
Topics: Aged; Creatinine; Etidronic Acid; Female; Hip Joint; Humans; Male; Organophosphonates; Organophospho | 1974 |