etidronate has been researched along with Osteoarthritis of Knee in 11 studies
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the frequency of upper gastrointestinal (GI) tract adverse events associated with risedronate during two (2-year) randomized, double-blind, parallel-group, placebo-controlled studies." | 2.71 | Upper gastrointestinal tract safety of daily oral risedronate in patients taking NSAIDs: a randomized, double-blind, placebo-controlled trial. ( Adami, S; Barton, IP; Bensen, WG; Cline, GA; Cohen, SB; Hosterman, MA; Pavelka, K, 2005) |
| "Alendronate treatment reduced bony osteophyte development." | 1.36 | In vivo microfocal computed tomography and micro-magnetic resonance imaging evaluation of antiresorptive and antiinflammatory drugs as preventive treatments of osteoarthritis in the rat. ( Doschak, MR; Jones, MD; Li, G; Maksymowych, WP; Tran, CW; Zernicke, RF, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (72.73) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iwamoto, J | 1 |
| Takeda, T | 1 |
| Sato, Y | 1 |
| Matsumoto, H | 1 |
| Jones, MD | 1 |
| Tran, CW | 1 |
| Li, G | 1 |
| Maksymowych, WP | 1 |
| Zernicke, RF | 1 |
| Doschak, MR | 1 |
| Bartlett, SJ | 1 |
| Ling, SM | 1 |
| Mayo, NE | 1 |
| Scott, SC | 1 |
| Bingham, CO | 4 |
| Spector, TD | 2 |
| Conaghan, PG | 2 |
| Buckland-Wright, JC | 3 |
| Garnero, P | 3 |
| Cline, GA | 5 |
| Beary, JF | 4 |
| Valent, DJ | 1 |
| Meyer, JM | 4 |
| Adami, S | 2 |
| Pavelka, K | 1 |
| Hosterman, MA | 1 |
| Barton, IP | 1 |
| Cohen, SB | 3 |
| Bensen, WG | 1 |
| Messent, EA | 1 |
| Ward, RJ | 1 |
| Tonkin, C | 1 |
| Dougados, M | 1 |
| Clauw, DJ | 1 |
| Pelletier, JP | 2 |
| Raynauld, JP | 2 |
| Strand, V | 1 |
| Simon, LS | 1 |
| Martel-Pelletier, J | 1 |
| Berthiaume, MJ | 1 |
| Abram, F | 1 |
| Choquette, D | 1 |
| Haraoui, B | 1 |
| Aronstein, WS | 1 |
| Christiansen, C | 1 |
| Fujita, T | 1 |
| Fujii, Y | 1 |
| Okada, SF | 1 |
| Miyauchi, A | 1 |
| Takagi, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical Intervention[NCT05204836] | Phase 1 | 56 participants (Anticipated) | Interventional | 2023-05-16 | Recruiting | ||
| A Randomized Placebo Controlled Trial Testing The Effect of Zoledronic Acid on Hip Osteoarthritis[NCT04303026] | Phase 3 | 70 participants (Anticipated) | Interventional | 2020-03-02 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for etidronate and Osteoarthritis of Knee
| Article | Year |
|---|---|
Effects of risedronate on osteoarthritis of the knee.
Topics: Animals; Calcium Channel Blockers; Cartilage; Diphosphonates; Etidronic Acid; Humans; Osteoarthritis | 2010 |
7 trials available for etidronate and Osteoarthritis of Knee
3 other studies available for etidronate and Osteoarthritis of Knee
| Article | Year |
|---|---|
In vivo microfocal computed tomography and micro-magnetic resonance imaging evaluation of antiresorptive and antiinflammatory drugs as preventive treatments of osteoarthritis in the rat.
Topics: Alendronate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Density Conservation Agents; Dis | 2010 |
Osteoporosis drug may protect joints.
Topics: Bone Density Conservation Agents; Etidronic Acid; Humans; Osteoarthritis, Knee; Risedronic Acid | 2006 |
Correlation between bone lesion changes and cartilage volume loss in patients with osteoarthritis of the knee as assessed by quantitative magnetic resonance imaging over a 24-month period.
Topics: Analysis of Variance; Bone and Bones; Bone Cysts; Cartilage, Articular; Diphosphonates; Disease Prog | 2008 |