etidronate has been researched along with Osteoarthritis, Knee in 11 studies
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
Osteoarthritis, Knee: Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the frequency of upper gastrointestinal (GI) tract adverse events associated with risedronate during two (2-year) randomized, double-blind, parallel-group, placebo-controlled studies." | 2.71 | Upper gastrointestinal tract safety of daily oral risedronate in patients taking NSAIDs: a randomized, double-blind, placebo-controlled trial. ( Adami, S; Barton, IP; Bensen, WG; Cline, GA; Cohen, SB; Hosterman, MA; Pavelka, K, 2005) |
| "Alendronate treatment reduced bony osteophyte development." | 1.36 | In vivo microfocal computed tomography and micro-magnetic resonance imaging evaluation of antiresorptive and antiinflammatory drugs as preventive treatments of osteoarthritis in the rat. ( Doschak, MR; Jones, MD; Li, G; Maksymowych, WP; Tran, CW; Zernicke, RF, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (72.73) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iwamoto, J | 1 |
| Takeda, T | 1 |
| Sato, Y | 1 |
| Matsumoto, H | 1 |
| Jones, MD | 1 |
| Tran, CW | 1 |
| Li, G | 1 |
| Maksymowych, WP | 1 |
| Zernicke, RF | 1 |
| Doschak, MR | 1 |
| Bartlett, SJ | 1 |
| Ling, SM | 1 |
| Mayo, NE | 1 |
| Scott, SC | 1 |
| Bingham, CO | 4 |
| Spector, TD | 2 |
| Conaghan, PG | 2 |
| Buckland-Wright, JC | 3 |
| Garnero, P | 3 |
| Cline, GA | 5 |
| Beary, JF | 4 |
| Valent, DJ | 1 |
| Meyer, JM | 4 |
| Adami, S | 2 |
| Pavelka, K | 1 |
| Hosterman, MA | 1 |
| Barton, IP | 1 |
| Cohen, SB | 3 |
| Bensen, WG | 1 |
| Messent, EA | 1 |
| Ward, RJ | 1 |
| Tonkin, C | 1 |
| Dougados, M | 1 |
| Clauw, DJ | 1 |
| Pelletier, JP | 2 |
| Raynauld, JP | 2 |
| Strand, V | 1 |
| Simon, LS | 1 |
| Martel-Pelletier, J | 1 |
| Berthiaume, MJ | 1 |
| Abram, F | 1 |
| Choquette, D | 1 |
| Haraoui, B | 1 |
| Aronstein, WS | 1 |
| Christiansen, C | 1 |
| Fujita, T | 1 |
| Fujii, Y | 1 |
| Okada, SF | 1 |
| Miyauchi, A | 1 |
| Takagi, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical Intervention[NCT05204836] | Phase 1 | 56 participants (Anticipated) | Interventional | 2023-05-16 | Recruiting | ||
| A Randomized Placebo Controlled Trial Testing The Effect of Zoledronic Acid on Hip Osteoarthritis[NCT04303026] | Phase 3 | 70 participants (Anticipated) | Interventional | 2020-03-02 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for etidronate and Osteoarthritis, Knee
| Article | Year |
|---|---|
Effects of risedronate on osteoarthritis of the knee.
Topics: Animals; Calcium Channel Blockers; Cartilage; Diphosphonates; Etidronic Acid; Humans; Osteoarthritis | 2010 |
7 trials available for etidronate and Osteoarthritis, Knee
3 other studies available for etidronate and Osteoarthritis, Knee
| Article | Year |
|---|---|
In vivo microfocal computed tomography and micro-magnetic resonance imaging evaluation of antiresorptive and antiinflammatory drugs as preventive treatments of osteoarthritis in the rat.
Topics: Alendronate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Density Conservation Agents; Dis | 2010 |
Osteoporosis drug may protect joints.
Topics: Bone Density Conservation Agents; Etidronic Acid; Humans; Osteoarthritis, Knee; Risedronic Acid | 2006 |
Correlation between bone lesion changes and cartilage volume loss in patients with osteoarthritis of the knee as assessed by quantitative magnetic resonance imaging over a 24-month period.
Topics: Analysis of Variance; Bone and Bones; Bone Cysts; Cartilage, Articular; Diphosphonates; Disease Prog | 2008 |