etidronate has been researched along with Oral Ulcer in 2 studies
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
Oral Ulcer: A loss of mucous substance of the mouth showing local excavation of the surface, resulting from the sloughing of inflammatory necrotic tissue. It is the result of a variety of causes, e.g., denture irritation, aphthous stomatitis (STOMATITIS, APHTHOUS); NOMA; necrotizing gingivitis (GINGIVITIS, NECROTIZING ULCERATIVE); TOOTHBRUSHING; and various irritants. (From Jablonski, Dictionary of Dentistry, 1992, p842)
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, there seems to be a limited awareness that oral bisphosphonates can also induce adverse effects in the soft tissues of the oral cavity, as indicated by the paucity of reported cases in the literature." | 1.38 | Pharmacovigilance of oral bisphosphonates: adverse effects manifesting in the soft tissue of the oral cavity. ( Kharazmi, M; Persson, U; Warfvinge, G, 2012) |
| "Most reports of osteonecrosis are attributed to the use of bisphosphonates administered intravenously for the treatment of bone disorders such as multiple myeloma." | 1.35 | Osteonecrosis associated with short-term oral administration of bisphosphonate. ( Harada, A; Sumi, Y; Takagi, Y, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takagi, Y | 1 |
| Sumi, Y | 1 |
| Harada, A | 1 |
| Kharazmi, M | 1 |
| Persson, U | 1 |
| Warfvinge, G | 1 |
2 other studies available for etidronate and Oral Ulcer
| Article | Year |
|---|---|
Osteonecrosis associated with short-term oral administration of bisphosphonate.
Topics: Administration, Oral; Aged; Bone Density Conservation Agents; Denture, Partial, Removable; Etidronic | 2009 |
Pharmacovigilance of oral bisphosphonates: adverse effects manifesting in the soft tissue of the oral cavity.
Topics: Administration, Oral; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Alendronate; | 2012 |