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etidronate and Injuries, Spinal Cord

etidronate has been researched along with Injuries, Spinal Cord in 22 studies

Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.

Research Excerpts

ExcerptRelevanceReference
"He developed bladder stones and electrohydraulic lithotripsy (EHL) was performed in May 2002."5.33Recurrent vesical calculi, hypercalciuria, and biochemical evidence of increased bone resorption in an adult male with paraplegia due to spinal cord injury: is there a role for intermittent oral disodium etidronate therapy for prevention of calcium phosph ( Buczynski, AZ; Fraser, WD; Grases, F; Heilberg, IP; Hughes, PL; Jonsson, O; Kohri, K; Schurch, B; Sett, P; Singh, G; Soni, BM; Tozawa, K; Vaidyanathan, S; Watson, ID; Wyndaele, JJ; Yasui, T, 2005)
"It is attributed to an increase in bone resorption and diminished bone formation characterized clinically by elevated serum calcium levels, hypercalciuria, increased risk of urinary lithiasis, and renal failure."5.29Successful treatment of immobilization hypercalcemia using calcitonin and etidronate. ( Cross, LL; Meythaler, JM; Tuel, SM, 1993)
"The goal of the present study was to use intravenous etidronate in the acute phase of heterotopic ossification (HO) in an attempt to achieve a high initial drug concentration at the site of the active ectopic ossification."3.68Intravenous disodium etidronate therapy in spinal cord injury patients with heterotopic ossification. ( Banovac, K; Bowker, JJ; Gonzalez, F; Wade, N, 1993)
"After discontinuation of drug therapy, recurrence was variable but less than expected."2.64Disodium etidronate in the prevention of postoperative recurrence of heterotopic ossification in spinal-cord injury patients. ( Miller, JM; Niemann, KM; Stover, SL, 1976)
"After patients with osteoporosis are identified, the challenge is to treat them appropriately."2.47Treatments for osteoporosis in people with a disability. ( Smith, EM, 2011)
"Neurogenic heterotopic ossification (NHO) is a frequent complication in spinal cord injury (SCI) that is often difficult to treat."2.41Neurogenic heterotopic ossification in spinal cord injury. ( Geurts, AC; van Kuijk, AA; van Kuppevelt, HJ, 2002)
"He developed bladder stones and electrohydraulic lithotripsy (EHL) was performed in May 2002."1.33Recurrent vesical calculi, hypercalciuria, and biochemical evidence of increased bone resorption in an adult male with paraplegia due to spinal cord injury: is there a role for intermittent oral disodium etidronate therapy for prevention of calcium phosph ( Buczynski, AZ; Fraser, WD; Grases, F; Heilberg, IP; Hughes, PL; Jonsson, O; Kohri, K; Schurch, B; Sett, P; Singh, G; Soni, BM; Tozawa, K; Vaidyanathan, S; Watson, ID; Wyndaele, JJ; Yasui, T, 2005)
"Formation of heterotopic ossification (HO) in soft tissue after spinal cord injury (SCI) is associated with various degrees of inflammation."1.32C-reactive protein and erythrocyte sedimentation rate in patients with heterotopic ossification after spinal cord injury. ( Banovac, K; Estrores, IM; Harrington, A, 2004)
"A case of extensive heterotopic ossification involving the left hip in a 16 year old girl who sustained non traumatic spinal paralysis at T4 ASIA scale A."1.31Management of immature heterotopic ossification (HO) of the hip. ( Banaovac, K; Bergman, SB; El Masry, WS; Jamil, F; Subbarao, JV, 2002)
"Etidronate was started intravenously (300 mg/day) for three days followed by oral therapy for six months (20 mg/kg/day)."1.30Treatment of heterotopic ossification after spinal cord injury. ( Banovac, K; Gonzalez, F; Renfree, KJ, 1997)
"Whereas the articular complications of heterotopic ossification have been well documented, the vascular complications are less well known."1.29[Heterotopic ossification and vascular compression]. ( Brissot, R; Gallien, P; Le Bot, MP; Nicolas, B; Rivier, I; Robineau, S; Sarkis, S, 1994)
"It is attributed to an increase in bone resorption and diminished bone formation characterized clinically by elevated serum calcium levels, hypercalciuria, increased risk of urinary lithiasis, and renal failure."1.29Successful treatment of immobilization hypercalcemia using calcitonin and etidronate. ( Cross, LL; Meythaler, JM; Tuel, SM, 1993)
" Diphosphonate therapy at a dosage of 10 mg/kg/day when prescribed an average of 26 days after diagnosis did not prevent radiographically evident progression of heterotopic ossification."1.27Diphosphonate treatment for heterotopic ossification in spinal cord injury patients. ( Alday, B; Garland, DE; Venos, KG; Vogt, JC, 1983)
"Other causes of hair loss were ruled out."1.27Telogen effluvium: hair loss after spinal cord injury. ( Dahlin, PA; George, J; Nérette, JC, 1984)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19906 (27.27)18.7374
1990's8 (36.36)18.2507
2000's7 (31.82)29.6817
2010's1 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Smith, EM1
Jamil, F1
Subbarao, JV2
Banaovac, K1
El Masry, WS1
Bergman, SB1
Banovac, K6
Sherman, AL1
Estores, IM1
Banovac, F1
Estrores, IM1
Harrington, A1
Vaidyanathan, S1
Watson, ID1
Jonsson, O1
Buczynski, AZ1
Grases, F1
Heilberg, IP1
Yasui, T1
Wyndaele, JJ1
Tozawa, K1
Kohri, K1
Schurch, B1
Hughes, PL1
Singh, G1
Soni, BM1
Sett, P1
Fraser, WD1
Freed, JH1
Hahn, H1
Menter, R1
Dillon, T1
Garland, DE1
Alday, B1
Venos, KG1
Vogt, JC1
Merli, GJ1
McElwain, GE1
Adler, AG1
Martin, JH1
Roberts, JD1
Schnall, B1
Ditunno, JF1
Dahlin, PA1
George, J1
Nérette, JC1
Finerman, GA1
Stover, SL2
Gallien, P1
Nicolas, B1
Le Bot, MP1
Robineau, S1
Rivier, I1
Sarkis, S1
Brissot, R1
Gonzalez, F3
Wade, N1
Bowker, JJ1
Biering-Sørensen, F1
Tøndevold, E1
Meythaler, JM1
Tuel, SM1
Cross, LL1
Pearson, EG1
Nance, PW1
Leslie, WD1
Ludwig, S1
Renfree, KJ1
Blankenship, LD1
Strommen, JA1
van Kuijk, AA1
Geurts, AC1
van Kuppevelt, HJ1
Niemann, KM1
Miller, JM1

Reviews

3 reviews available for etidronate and Injuries, Spinal Cord

ArticleYear
Treatments for osteoporosis in people with a disability.
    PM & R : the journal of injury, function, and rehabilitation, 2011, Volume: 3, Issue:2

    Topics: Bone Density; Bone Density Conservation Agents; Diphosphonates; Disabled Persons; Etidronic Acid; Hu

2011
Prevention and treatment of heterotopic ossification after spinal cord injury.
    The journal of spinal cord medicine, 2004, Volume: 27, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; Etidronic Acid; Humans; Ossifica

2004
Neurogenic heterotopic ossification in spinal cord injury.
    Spinal cord, 2002, Volume: 40, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcitonin; Diagnosis, Differential; Etidronic Acid; Glucoc

2002

Trials

3 trials available for etidronate and Injuries, Spinal Cord

ArticleYear
Evaluation and management of heterotopic ossification in patients with spinal cord injury.
    Spinal cord, 1997, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Etidronic Acid; Female; Humans; Male; Middle Aged; Ossification, Heterotopic; Rad

1997
Cyclical etidronate: its effect on bone density in patients with acute spinal cord injury.
    Archives of physical medicine and rehabilitation, 1997, Volume: 78, Issue:3

    Topics: Acute Disease; Adult; Bone Density; Bone Resorption; Drug Administration Schedule; Etidronic Acid; F

1997
Disodium etidronate in the prevention of postoperative recurrence of heterotopic ossification in spinal-cord injury patients.
    The Journal of bone and joint surgery. American volume, 1976, Volume: 58, Issue:5

    Topics: Adult; Etidronic Acid; Humans; Myositis Ossificans; Organophosphorus Compounds; Postoperative Care;

1976

Other Studies

16 other studies available for etidronate and Injuries, Spinal Cord

ArticleYear
Management of immature heterotopic ossification (HO) of the hip.
    Spinal cord, 2002, Volume: 40, Issue:8

    Topics: Adolescent; Etidronic Acid; Female; Hip; Humans; Ossification, Heterotopic; Paraplegia; Radiography;

2002
C-reactive protein and erythrocyte sedimentation rate in patients with heterotopic ossification after spinal cord injury.
    The journal of spinal cord medicine, 2004, Volume: 27, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Sedimentation; C-Reactive Protein; Etidronic A

2004
Recurrent vesical calculi, hypercalciuria, and biochemical evidence of increased bone resorption in an adult male with paraplegia due to spinal cord injury: is there a role for intermittent oral disodium etidronate therapy for prevention of calcium phosph
    Spinal cord, 2005, Volume: 43, Issue:5

    Topics: Adult; Bone Resorption; Calcium; Etidronic Acid; Follow-Up Studies; Humans; International Cooperatio

2005
The use of the three-phase bone scan in the early diagnosis of heterotopic ossification (HO) and in the evaluation of Didronel therapy.
    Paraplegia, 1982, Volume: 20, Issue:4

    Topics: Diphosphonates; Etidronic Acid; Hip Joint; Humans; Ossification, Heterotopic; Radionuclide Imaging;

1982
Diphosphonate treatment for heterotopic ossification in spinal cord injury patients.
    Clinical orthopaedics and related research, 1983, Issue:176

    Topics: Adolescent; Adult; Etidronic Acid; Female; Hip Joint; Humans; Male; Ossification, Heterotopic; Radio

1983
Immobilization hypercalcemia in acute spinal cord injury treated with etidronate.
    Archives of internal medicine, 1984, Volume: 144, Issue:6

    Topics: Acute Disease; Adult; Etidronic Acid; Humans; Hypercalcemia; Immobilization; Male; Spinal Cord Injur

1984
Telogen effluvium: hair loss after spinal cord injury.
    Archives of physical medicine and rehabilitation, 1984, Volume: 65, Issue:8

    Topics: Adult; Alopecia; Etidronic Acid; Humans; Hysteria; Male; Ossification, Heterotopic; Spinal Cord Inju

1984
Heterotopic ossification following hip replacement or spinal cord injury. Two clinical studies with EHDP.
    Metabolic bone disease & related research, 1981, Volume: 3, Issue:4-5

    Topics: Double-Blind Method; Etidronic Acid; Hip Prosthesis; Humans; Ossification, Heterotopic; Placebos; Ra

1981
[Heterotopic ossification and vascular compression].
    Revue du rhumatisme (Ed. francaise : 1993), 1994, Volume: 61, Issue:11

    Topics: Adult; Craniocerebral Trauma; Etidronic Acid; Femoral Vein; Humans; Indomethacin; Male; Middle Aged;

1994
Intravenous disodium etidronate therapy in spinal cord injury patients with heterotopic ossification.
    Paraplegia, 1993, Volume: 31, Issue:10

    Topics: Administration, Oral; Adolescent; Adult; Drug Administration Schedule; Edema; Etidronic Acid; Female

1993
Indomethacin and disodium etidronate for the prevention of recurrence of heterotopic ossification after surgical resection. Two case reports.
    Paraplegia, 1993, Volume: 31, Issue:8

    Topics: Adolescent; Adult; Etidronic Acid; Hip; Humans; Indomethacin; Male; Ossification, Heterotopic; Recur

1993
Successful treatment of immobilization hypercalcemia using calcitonin and etidronate.
    Archives of physical medicine and rehabilitation, 1993, Volume: 74, Issue:3

    Topics: Adolescent; Adult; Bone Resorption; Calcitonin; Drug Therapy, Combination; Etidronic Acid; Female; H

1993
Treatment of heterotopic ossification after spinal cord injury.
    The journal of spinal cord medicine, 1997, Volume: 20, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Dose-Response Relationship, Drug; Drug Administration Sched

1997
The effect of etidronate on late development of heterotopic ossification after spinal cord injury.
    The journal of spinal cord medicine, 2000,Spring, Volume: 23, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Etidronic Acid; Female; Follow-Up Studies; Humans; Infusion

2000
27-year-old man with a swollen leg.
    Mayo Clinic proceedings, 2000, Volume: 75, Issue:9

    Topics: Adult; Cervical Vertebrae; Diagnosis, Differential; Edema; Etidronic Acid; Exercise Therapy; Humans;

2000
Pseudoarthrosis in heterotopic ossification in spinal cord-injured patients.
    American journal of physical medicine & rehabilitation, 1990, Volume: 69, Issue:2

    Topics: Aged; Ankylosis; Craniocerebral Trauma; Etidronic Acid; Humans; Male; Middle Aged; Ossification, Het

1990