etidronate and Hyperparathyroidism
etidronate has been researched along with Hyperparathyroidism in 26 studies
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
Hyperparathyroidism: A condition of abnormally elevated output of PARATHYROID HORMONE (or PTH) triggering responses that increase blood CALCIUM. It is characterized by HYPERCALCEMIA and BONE RESORPTION, eventually leading to bone diseases. PRIMARY HYPERPARATHYROIDISM is caused by parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. SECONDARY HYPERPARATHYROIDISM is increased PTH secretion in response to HYPOCALCEMIA, usually caused by chronic KIDNEY DISEASES.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"To define the nature, incidence and consequence of a possible interaction between etidronate (for the treatment of hypercalcemia) and methylene diphosphonate labelled with technetium-99m (99mTc-MDP) (for bone scanning)." | 3.69 | Etidronate therapy decreases the sensitivity of bone scanning with methylene diphosphonate labelled with technetium-99m. ( Line, BR; Malfetano, J; Murphy, KJ, 1997) |
"Urinary deoxypyridinoline, a bone resorption marker, decreased by 46." | 2.73 | Risedronate and ergocalciferol prevent hip fracture in elderly men with Parkinson disease. ( Honda, Y; Iwamoto, J; Sato, Y, 2007) |
"Indomethacin was effective in only one of five patients to whom it was given, and EHDP was effective also in only one of five patients." | 2.65 | Comparative study of available medical therapy for hypercalcemia of malignancy. ( Heath, DA; Mundy, GR; Wilkinson, R, 1983) |
"Histologic proof of renal osteodystrophy had been obtained in all patients." | 1.26 | Bone scintigraphy in renal osteodystrophy. ( de Graaf, P; de Graeff, J; Pauwels, EK; Schicht, IM; te Velde, J, 1978) |
Research
Studies (26)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 17 (65.38) | 18.7374 |
1990's | 6 (23.08) | 18.2507 |
2000's | 2 (7.69) | 29.6817 |
2010's | 1 (3.85) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Brookler, KH | 1 |
Sato, Y | 2 |
Honda, Y | 2 |
Umeno, K | 1 |
Hayashida, N | 1 |
Iwamoto, J | 2 |
Takeda, T | 1 |
Matsumoto, H | 1 |
Mundy, GR | 2 |
Wilkinson, R | 1 |
Heath, DA | 1 |
Delmas, PD | 1 |
Meunier, PJ | 1 |
Fogelman, I | 2 |
Bessent, RG | 2 |
Gay, JD | 1 |
Poznanski, WJ | 1 |
Licata, AA | 1 |
O'Hanlon, E | 1 |
De Graaf, P | 2 |
Schicht, IM | 2 |
Te Velde, J | 2 |
Pauwels, EK | 2 |
Kleiverda, K | 1 |
De Graeff, J | 2 |
Amoroso, A | 1 |
Petroni, S | 1 |
Cavina, G | 1 |
Caccavo, D | 1 |
Raisz, LG | 1 |
Steiniche, T | 1 |
Rodan, GA | 1 |
Seedor, JG | 1 |
Balena, R | 1 |
Reasner, CA | 1 |
Stone, MD | 1 |
Hosking, DJ | 1 |
Ballah, A | 1 |
Forbes, RB | 1 |
Grant, DJ | 1 |
MacWalter, RS | 1 |
Murphy, KJ | 1 |
Line, BR | 1 |
Malfetano, J | 1 |
Alexandre, C | 1 |
Chapuy, MC | 1 |
Meunier, P | 1 |
Walton, RJ | 1 |
Smith, R | 1 |
Russell, RG | 1 |
Kaplan, RA | 1 |
Geho, WB | 1 |
Poindexter, C | 1 |
Haussler, M | 1 |
Dietz, GW | 1 |
Pak, CY | 1 |
Greig, WR | 1 |
Boyle, IT | 1 |
Rosen, C | 1 |
Segal, H | 1 |
Hartz, CE | 1 |
Mroz, F | 1 |
Carlton, E | 1 |
Foldes, J | 1 |
Halperin, Y | 1 |
Kidroni, G | 1 |
Menczel, J | 1 |
Sasaki, H | 1 |
Miyake, K | 1 |
Okumura, M | 1 |
Eimoto, T | 1 |
Fleisch, H | 1 |
Clinical Trials (1)
Trial Overview
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Phase I Pilot Trial to Study the Safety and Efficacy of Concomitant Radiotherapy and Zoledronic Acid for the Palliation of Bone Metastases From Breast Cancer, Prostate Cancer and Lung Cancer[NCT00264420] | Phase 1 | 4 participants (Actual) | Interventional | 2005-12-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Reviews
3 reviews available for etidronate and Hyperparathyroidism
Article | Year |
---|---|
Bone histomorphometry in the pathophysiological evaluation of primary and secondary osteoporosis and various treatment modalities.
Topics: Adult; Aged; Aging; Benzothiadiazines; Bone and Bones; Calcium; Diuretics; Estrogens; Etidronic Acid | 1995 |
Preclinical pharmacology of alendronate.
Topics: Alendronate; Animals; Calcification, Physiologic; Diphosphonates; Disease Models, Animal; Estrogens; | 1993 |
[Biphosphonate as a therapeutic drug--experimental studies and clinical application].
Topics: Animals; Calcinosis; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hypercalcemia; Hyperpar | 1985 |
Trials
4 trials available for etidronate and Hyperparathyroidism
Article | Year |
---|---|
The prevention of hip fracture with menatetrenone and risedronate plus calcium supplementation in elderly patients with Alzheimer disease: a randomized controlled trial.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Bone Density; Bone Density Conservation Agents; Etidroni | 2011 |
Risedronate and ergocalciferol prevent hip fracture in elderly men with Parkinson disease.
Topics: Aged; Aged, 80 and over; Amino Acids; Biomarkers; Bone Density; Bone Density Conservation Agents; Bo | 2007 |
Comparative study of available medical therapy for hypercalcemia of malignancy.
Topics: Administration, Oral; Adult; Aged; Calcium; Clinical Trials as Topic; Diphosphonates; Etidronic Acid | 1983 |
Metabolic effects of diphosphonate in primary hyperparathyroidism.
Topics: Adult; Aged; Alkaline Phosphatase; Bone and Bones; Calcium; Clinical Trials as Topic; Cyclic AMP; Di | 1977 |
Other Studies
19 other studies available for etidronate and Hyperparathyroidism
Article | Year |
---|---|
Monaural diplacusis with tinnitus, aural fullness, hyperacusis, and sensorineural hearing loss.
Topics: Bone Density Conservation Agents; Diabetes Mellitus, Type 2; Etidronic Acid; Hearing Loss, Sensorine | 2009 |
Medical management of primary hyperparathyroidism.
Topics: Aged; Clodronic Acid; Estrogens; Etidronic Acid; Humans; Hyperparathyroidism; Middle Aged | 1984 |
[Diphosphonates in the treatment of hypercalcemia].
Topics: Bone Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hypercalcemia; Hyperparathyr | 1984 |
The effect of parathyroid hormone on technetium-99m pyrophosphate distribution in rats.
Topics: Animals; Diphosphates; Etidronic Acid; Humans; Hyperparathyroidism; Organotechnetium Compounds; Radi | 1981 |
Hyperparathyroidism in Paget's disease of bone.
Topics: Aged; Calcium; Cyclic AMP; Etidronic Acid; Female; Humans; Hyperparathyroidism; Male; Middle Aged; O | 1983 |
Treatment of hyperparathyroidism with etidronate disodium.
Topics: Aged; Alkaline Phosphatase; Calcium; Etidronic Acid; Female; Humans; Hyperparathyroidism; Pain; Phos | 1983 |
Quantitative bone scintigraphy in evaluating treatment of renal osteodystrophy.
Topics: Bone and Bones; Chronic Kidney Disease-Mineral and Bone Disorder; Etidronic Acid; Humans; Hyperparat | 1983 |
[Hypercalcemic syndromes].
Topics: Adrenal Cortex Hormones; Adult; Benzothiadiazines; Child; Diphosphonates; Diuretics; Etidronic Acid; | 1984 |
New diphosphonates to block bone resorption.
Topics: Animals; Bone Resorption; Breast Neoplasms; Clodronic Acid; Diphosphonates; Double-Blind Method; Eti | 1980 |
Acute changes in calcium homeostasis during treatment of primary hyperparathyroidism with risedronate.
Topics: Administration, Oral; Aged; Alkaline Phosphatase; Analysis of Variance; Bone Resorption; Calcium; Et | 1993 |
Cyclical etidronate and calcium carbonate (with citrate) supplementation for osteoporosis unmasking primary hyperparathyroidism.
Topics: Aged; Aged, 80 and over; Antacids; Calcium; Calcium Carbonate; Citrates; Citric Acid; Diagnosis, Dif | 1995 |
Etidronate therapy decreases the sensitivity of bone scanning with methylene diphosphonate labelled with technetium-99m.
Topics: Administration, Oral; Aged; Bone and Bones; Bone Diseases; Bone Neoplasms; Contraindications; Drug I | 1997 |
Bone scintigraphy in renal osteodystrophy.
Topics: Adolescent; Adult; Alkaline Phosphatase; Bone and Bones; Chronic Kidney Disease-Mineral and Bone Dis | 1978 |
[The hypocalcemia test, using human and salmon synthetic calcitonins. Paradoxical hypercalcemic responses. Responses in patients with Paget's disease treated with EHDP].
Topics: Calcitonin; Calcium; Dose-Response Relationship, Drug; Etidronic Acid; Hormones; Humans; Hyperparath | 1979 |
Effects of a diphosphonate (disodium etidronate: EHDP) on phosphate metabolism in Paget's disease of bone, primary hyperparathyroidism and type I hypophosphataemic rickets.
Topics: Etidronic Acid; Humans; Hyperparathyroidism; Hypophosphatemia, Familial; Kidney; Kidney Tubules; Org | 1976 |
Skeletal uptake of Tc-99m HEDP in primary hyperparathyroidism.
Topics: Bone and Bones; Etidronic Acid; Humans; Hyperparathyroidism; Radionuclide Imaging; Technetium | 1977 |
Primary hyperparathyroidism in an elderly patient with multiple myeloma.
Topics: Aged; Aged, 80 and over; Calcium; Cyclic AMP; Etidronic Acid; Humans; Hypercalcemia; Hyperparathyroi | 1992 |
Medical treatment of primary hyperparathyroidism: effects on parathormone and vitamin D metabolites.
Topics: Calcitonin; Cimetidine; Dihydroxycholecalciferols; Drug Therapy, Combination; Etidronic Acid; Female | 1987 |
[Failure of cimetidine and etidronate disodium to suppress parathyroid hormone level and hypercalcemia in primary hyperparathyroidism].
Topics: Adenoma; Aged; Alkaline Phosphatase; Cimetidine; Etidronic Acid; Humans; Hypercalcemia; Hyperparathy | 1988 |