etidronate has been researched along with Genetic Predisposition in 3 studies
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pseudoxanthoma elasticum is a prototype of heritable ectopic mineralization disorders, with phenotypic overlap with generalized arterial calcification of infancy and arterial calcification due to CD73 deficiency." | 2.55 | Insights into Pathomechanisms and Treatment Development in Heritable Ectopic Mineralization Disorders: Summary of the PXE International Biennial Research Symposium-2016. ( Li, Q; Terry, SF; Uitto, J; van de Wetering, K; Váradi, A, 2017) |
| "Treatment with etidronate had no effect on bone parameters in the WT mice; however, the Enpp1-/- mice displayed an increased structural model index (SMI; P<0." | 1.42 | Effects of etidronate on the Enpp1⁻/⁻ mouse model of generalized arterial calcification of infancy. ( Huesa, C; MacRae, VE; Millán, JL; Staines, KA, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uitto, J | 1 |
| Li, Q | 1 |
| van de Wetering, K | 1 |
| Váradi, A | 1 |
| Terry, SF | 1 |
| Huesa, C | 1 |
| Staines, KA | 1 |
| Millán, JL | 1 |
| MacRae, VE | 1 |
| Edouard, T | 1 |
| Chabot, G | 1 |
| Miro, J | 1 |
| Buhas, DC | 1 |
| Nitschke, Y | 1 |
| Lapierre, C | 1 |
| Rutsch, F | 1 |
| Alos, N | 1 |
1 review available for etidronate and Genetic Predisposition
| Article | Year |
|---|---|
Insights into Pathomechanisms and Treatment Development in Heritable Ectopic Mineralization Disorders: Summary of the PXE International Biennial Research Symposium-2016.
Topics: 5'-Nucleotidase; Alkaline Phosphatase; Animals; Biopsy, Needle; Clinical Trials as Topic; Congresses | 2017 |
2 other studies available for etidronate and Genetic Predisposition
| Article | Year |
|---|---|
Effects of etidronate on the Enpp1⁻/⁻ mouse model of generalized arterial calcification of infancy.
Topics: Animals; Aorta; Bone Density; Bone Density Conservation Agents; Calcification, Physiologic; Disease | 2015 |
Efficacy and safety of 2-year etidronate treatment in a child with generalized arterial calcification of infancy.
Topics: Absorptiometry, Photon; Angiography; Bone Density Conservation Agents; Diagnosis, Differential; DNA; | 2011 |