etidronate has been researched along with Dental Caries in 10 studies
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
Dental Caries: Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (60.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, J | 1 |
| Gil, M | 1 |
| Khorashadi, S | 1 |
| Chen, G | 1 |
| Lee, C | 1 |
| Ishida, Y | 1 |
| Nagai, M | 1 |
| Wada, S | 1 |
| Ishikawa-Nagai, S | 1 |
| Da Silva, JD | 1 |
| Morago, A | 1 |
| Ordinola-Zapata, R | 1 |
| Ferrer-Luque, CM | 1 |
| Baca, P | 1 |
| Ruiz-Linares, M | 1 |
| Arias-Moliz, MT | 1 |
| Hasegawa, T | 1 |
| Ri, S | 1 |
| Umeda, M | 1 |
| Komatsubara, H | 1 |
| Kobayashi, M | 1 |
| Shigeta, T | 1 |
| Yoshitomi, I | 1 |
| Ikeda, H | 1 |
| Shibuya, Y | 1 |
| Asahina, I | 1 |
| Komori, T | 1 |
| Wefel, JS | 1 |
| Harless, JD | 1 |
| Wöltgens, JH | 3 |
| Koulourides, T | 1 |
| White, WD | 1 |
| Nancollas, GH | 1 |
| Houwink, B | 2 |
| Bervoets, TJ | 1 |
| Christoffersen, J | 1 |
| Christoffersen, MR | 1 |
| Ruben, J | 1 |
| Arends, J | 1 |
| Shimizu, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Using Etidronate in Sodium Hypochlorite Versus Sodium Hypochlorite Irrigating Solution on the Intensity of Postoperative Pain and Bacterial Load Reduction in Patients With Necrotic Pulp: A Randomized Clinical Trial[NCT04035330] | 34 participants (Anticipated) | Interventional | 2019-09-30 | Not yet recruiting | |||
| Prevention of Enamel Demineralization in Fixed Appliance Orthodontic Patients Using UDMA-K18 Sealant to Prevent Microbial Attachment Compared to a UDMA Control and no Sealant, a Randomized Split Mouth Clinical Trial[NCT03306433] | 16 participants (Actual) | Interventional | 2018-01-08 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The mineral density immediately below the surface of the tooth will lower if left unprotected to some extent. (NCT03306433)
Timeframe: Visit Window: 3-4 weeks.
| Intervention | Canary Number (Mean) |
|---|---|
| UDMA-K18 | 23.424 |
| UDMA-control | 31.125 |
| Adhesive Control | 35.563 |
The WSL Index is from 0 (no lesion) to 4 (severe lesion) (NCT03306433)
Timeframe: Visit Window: 3-4 weeks.
| Intervention | White spot Index (Median) |
|---|---|
| UDMA-K18 | 0 |
| UDMA-control | 2 |
| Adhesive Control | 2 |
10 other studies available for etidronate and Dental Caries
| Article | Year |
|---|---|
Efficacy of bisphosphonates in detection of early enamel caries using NIR fluorescence imaging and inhibition of caries progression.
Topics: Bone Density Conservation Agents; Contrast Media; Dental Caries; Dental Enamel; Diphosphonates; Dise | 2021 |
Influence of Smear Layer on the Antimicrobial Activity of a Sodium Hypochlorite/Etidronic Acid Irrigating Solution in Infected Dentin.
Topics: Anti-Infective Agents; Bacteria; Bicuspid; Dental Caries; Dental Pulp Cavity; Dentin; Enterococcus f | 2016 |
The observational study of delayed wound healing after tooth extraction in patients receiving oral bisphosphonate therapy.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Alendronate; Antibiotic Prophylaxis; Bisphosph | 2013 |
Comparison of artificial white spots by microradiography and polarized light microscopy.
Topics: Decalcification Technique; Dental Caries; Dental Enamel; Durapatite; Etidronic Acid; Gels; Humans; H | 1984 |
Comparison of diphosphonate effects on enamel in vitro and in vivo.
Topics: Animals; Cattle; Dental Caries; Dental Enamel; Etidronic Acid; Fluorides; Hardness; Humans; In Vitro | 1983 |
A rotating disc study of enamel dissolution in HEDP solution under simulated white spot conditions.
Topics: Animals; Calcium; Cattle; Chemical Precipitation; Dental Caries; Dental Enamel; Dental Enamel Solubi | 1980 |
Influence of the diphosphonate EHDP on the remineralization of artificial caries in human enamel.
Topics: Birefringence; Dental Caries; Dental Enamel; Etidronic Acid; Humans; Tooth Calcification | 1979 |
Influence of diphosphonates and sodium fluoride on the development of artificial caries. II. Morphological aspects.
Topics: Animals; Calcium; Cattle; Dental Caries; Etidronic Acid; Fluorides, Topical; Organophosphonates; Org | 1976 |
The effect of EHDP concentration on enamel demineralization in vitro.
Topics: Animals; Calcium; Cariostatic Agents; Cattle; Dental Caries; Dental Enamel; Dental Enamel Solubility | 1991 |
[Effect of HEBP on the remineralization of acid-etched enamel].
Topics: Acid Etching, Dental; Animals; Cattle; Dental Caries; Dental Enamel; Etidronic Acid; Tooth Remineral | 1986 |