etidronate has been researched along with Cystic Fibrosis in 3 studies
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Disturbances in bone mineralization are frequent in cystic fibrosis but few studies have focused on the use of biphosphonates in this indication, and none on the use of oral etidronate." | 3.72 | [Effect of oral biphosphonates in patients with cystic fibrosis and low bone mineral density]. ( Audran, M; Duveau, E; Giniès, JL; Leblanc, M; Leboucher, B; Ringuier, B; Troussier, F, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haworth, CS | 1 |
| Sharples, L | 1 |
| Hughes, V | 1 |
| Elkin, SL | 1 |
| Hodson, ME | 1 |
| Conway, SP | 1 |
| Etherington, C | 1 |
| Elborn, JS | 1 |
| Rendall, J | 1 |
| Wheaton, E | 1 |
| Kadri, E | 1 |
| Elliott, J | 1 |
| Barker, HC | 1 |
| Bearcroft, PW | 1 |
| Hlaing, T | 1 |
| Compston, JE | 1 |
| Ringuier, B | 1 |
| Leboucher, B | 1 |
| Leblanc, M | 1 |
| Troussier, F | 1 |
| Duveau, E | 1 |
| Audran, M | 1 |
| Giniès, JL | 1 |
| Carson, MR | 1 |
| Winter, MC | 1 |
| Travis, SM | 1 |
| Welsh, MJ | 1 |
1 trial available for etidronate and Cystic Fibrosis
| Article | Year |
|---|---|
Multicentre trial of weekly risedronate on bone density in adults with cystic fibrosis.
Topics: Adult; Bone Density; Bone Density Conservation Agents; Cystic Fibrosis; Drug Administration Schedule | 2011 |
2 other studies available for etidronate and Cystic Fibrosis
| Article | Year |
|---|---|
[Effect of oral biphosphonates in patients with cystic fibrosis and low bone mineral density].
Topics: Adult; Bone Density; Calcium; Child; Cystic Fibrosis; Dietary Supplements; Etidronic Acid; Humans; R | 2004 |
Pyrophosphate stimulates wild-type and mutant cystic fibrosis transmembrane conductance regulator Cl- channels.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Membrane; Chloride Channels; Cyclic AMP; Cyclic AMP | 1995 |