etidronate has been researched along with Chagas Disease in 4 studies
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A murine model of acute Chagas' disease was used, in which experimental animals were infected with 10(3) trypomastigotes and intravenous treatment was started 24 h post-infection." | 1.32 | Antiparasitic activity of risedronate in a murine model of acute Chagas' disease. ( Baptista, MM; Britto, CC; de Castro, SL; Docampo, R; Garzoni, LR; Meirelles, Mde N; Oldfield, E; Urbina, JA; Waghabi, MC, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Demoro, B | 1 |
| Caruso, F | 1 |
| Rossi, M | 1 |
| Benítez, D | 1 |
| Gonzalez, M | 1 |
| Cerecetto, H | 1 |
| Parajón-Costa, B | 1 |
| Castiglioni, J | 1 |
| Galizzi, M | 1 |
| Docampo, R | 3 |
| Otero, L | 1 |
| Gambino, D | 1 |
| Garzoni, LR | 2 |
| Caldera, A | 1 |
| Meirelles, Mde N | 2 |
| de Castro, SL | 2 |
| Meints, GA | 1 |
| Oldfield, E | 2 |
| Urbina, JA | 2 |
| Waghabi, MC | 1 |
| Baptista, MM | 1 |
| Britto, CC | 1 |
| Bouzahzah, B | 1 |
| Jelicks, LA | 1 |
| Morris, SA | 1 |
| Weiss, LM | 1 |
| Tanowitz, HB | 1 |
4 other studies available for etidronate and Chagas Disease
| Article | Year |
|---|---|
Risedronate metal complexes potentially active against Chagas disease.
Topics: Animals; Chagas Disease; Coordination Complexes; Etidronic Acid; Geranyltranstransferase; Models, Ch | 2010 |
Selective in vitro effects of the farnesyl pyrophosphate synthase inhibitor risedronate on Trypanosoma cruzi.
Topics: Alkyl and Aryl Transferases; Animals; Cells, Cultured; Chagas Disease; Chlorocebus aethiops; Enzyme | 2004 |
Antiparasitic activity of risedronate in a murine model of acute Chagas' disease.
Topics: Acute Disease; Alkyl and Aryl Transferases; Animals; Chagas Disease; Disease Models, Animal; Enzyme | 2004 |
Risedronate in the treatment of Murine Chagas' disease.
Topics: Animals; Chagas Cardiomyopathy; Chagas Disease; Disease Models, Animal; Etidronic Acid; Mice; Mice, | 2005 |