etidronate has been researched along with Calcification, Pathologic in 95 studies
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report a beneficial effect of high-dose etidronate, one of the bisphosphonates, on periarticular calcinosis in a case of arterial and periarticular BCP crystal deposition disease." | 7.72 | [Beneficial effect of high-dose etidronate on periarticular calcinosis associated with arterial and periarticular basic calcium phosphate (BCP) crystal deposition disease]. ( Ide, M; Ito, G; Ozaki, S; Suzuki, Y; Uehara, R, 2003) |
| "The use of disodium etidronate (EHDP) for the treatment of calcinosis is complicated by the threat of drug-induced inhibition of skeletal mineralization." | 7.66 | Focal mineralization defect during disodium etidronate treatment of calcinosis. ( Weinstein, RS, 1982) |
| "Oral etidronate has been used for 3 weeks, after failure of classical treatment." | 5.34 | [Etidronate per os in subcutaneous fat necrosis with hypercalcemia and nephrocalcinosis]. ( Bottu, J; Trullemans, B; Van Nieuwenhuyse, JP, 2007) |
| " We report a beneficial effect of high-dose etidronate, one of the bisphosphonates, on periarticular calcinosis in a case of arterial and periarticular BCP crystal deposition disease." | 3.72 | [Beneficial effect of high-dose etidronate on periarticular calcinosis associated with arterial and periarticular basic calcium phosphate (BCP) crystal deposition disease]. ( Ide, M; Ito, G; Ozaki, S; Suzuki, Y; Uehara, R, 2003) |
| "The use of disodium etidronate (EHDP) for the treatment of calcinosis is complicated by the threat of drug-induced inhibition of skeletal mineralization." | 3.66 | Focal mineralization defect during disodium etidronate treatment of calcinosis. ( Weinstein, RS, 1982) |
| "A 46-year-old woman with the CRST variant of scleroderma (calcinosis, Raynaud's phenomenon, sclerodactyly, and telangiectasis) was treated with a diphosphonate (disodium etidronate) in an effort to reduce her dystrophic calcifications or retard their progression." | 3.65 | Appearance of a gastric ulcer during diphosphonate therapy in a woman with CRST syndrome. ( Saunders, RL, 1977) |
| "Statins are not effective in reducing atherosclerotic plaques of the abdominal aorta, and accumulating evidence suggests that bisphosphonates have the potential to induce the regression of atherosclerotic plaques of the abdominal aorta." | 2.78 | Atorvastatin, etidronate, or both in patients at high risk for atherosclerotic aortic plaques: a randomized, controlled trial. ( Inazu, T; Kawahara, C; Kawahara, T; Nishikawa, M; Sakai, K; Suzuki, G, 2013) |
| "Etidronate was given orally at the dose of 200 mg just before sleep on the day of dialysis, which was performed three times per week." | 2.71 | Inhibitory effects of etidronate on the progression of vascular calcification in hemodialysis patients. ( Aizawa, S; Hashiba, H; Kogo, H; Shigematsu, T; Tamura, K, 2004) |
| "Hypercalcemia was confirmed by laboratory examination." | 2.53 | Systemic lupus erythematosus-related hypercalcemia with ectopic calcinosis. ( Huang, L; Zhang, X; Zhao, L, 2016) |
| "Treatment with etidronate, 400 mg daily, induced total regression of severe, disabling periarticular calcifications during a treatment period of 42 months in a patient with chronic kidney disease on dialysis treatment." | 1.36 | [Regression of severe periarticular calcifications during treatment with bisphosphonate in a dialysis patient]. ( Larsen, NA; Obad, D; Pedersen, EB, 2010) |
| "Thirteen Japanese type 2 diabetes postmenopausal women with newly diagnosed osteoporosis (osteoporosis group) and 13 age- and weight-matched diabetic women with normal bone mineral density (control group) were enrolled in this 1-year prospective study." | 1.36 | Effects of treatment with risedronate and alfacalcidol on progression of atherosclerosis in postmenopausal women with type 2 diabetes mellitus accompanied with osteoporosis. ( Hayashi, K; Kanazawa, I; Shimizu, T; Sugimoto, T; Takase, H; Yamaguchi, T, 2010) |
| "Oral etidronate has been used for 3 weeks, after failure of classical treatment." | 1.34 | [Etidronate per os in subcutaneous fat necrosis with hypercalcemia and nephrocalcinosis]. ( Bottu, J; Trullemans, B; Van Nieuwenhuyse, JP, 2007) |
| " Our data show that ED at a dosage that suppresses bone metabolism markedly inhibits vascular calcification in rats with renal failure." | 1.33 | Effect of etidronate on aortic calcification and bone metabolism in calcitriol-treated rats with subtotal nephrectomy. ( Aizawa, S; Hashiba, H; Kogo, H; Suzuki, Y; Tamura, H; Tamura, K, 2005) |
| "Calciphylaxis is a local tissue calcific reaction at the site of an injection of challenger substance given a critical time period after the oral administration of a sensitizer substance such as dihydrotachysterol (DHT), vitamin D or parathormone." | 1.27 | Cutaneous calciphylactic reactions in the mouse and the rat and the effects of diphosphonates on the reaction in the rat. ( McClure, J; Miller, S; Vernon-Roberts, E, 1984) |
| "Calcium content was high in thrombus and increased in all zones with time, in both groups, but the deposition was less in the group treated with hydroxyethylene diphosphonate." | 1.27 | Quantification of regional platelet and calcium deposition on pericardial tissue valve prostheses in calves and effect of hydroxyethylene diphosphonate. ( Chesebro, JH; Dewanjee, MK; Didisheim, P; Edwards, WD; Kaye, MP; Lenker, J; Mackey, ST; Solis, E; Zollman, PE, 1986) |
| " Animals received daily subcutaneous injections of the drug (1, 5, 10, 15, or 25 mg/kg/24 hr) for 21 days with maximal inhibition of bioprosthetic heart valve calcification at a dosage of 15 mg/kg/24 hr (calcium level of diphosphonate-treated bioprostheses 3." | 1.27 | Prevention of leaflet calcification of bioprosthetic heart valves with diphosphonate injection therapy. Experimental studies of optimal dosages and therapeutic durations. ( Levy, RJ; Lund, SA; Schoen, FJ; Smith, MS, 1987) |
| "Transient hypercalcemia was attributed to immobilization." | 1.26 | Tumoral calcinosis. Observations during six years. ( Haas, HG; Lauffenburger, T; Leicht, E; Seeliger, H; Tkocz, HJ, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (47.37) | 18.7374 |
| 1990's | 17 (17.89) | 18.2507 |
| 2000's | 18 (18.95) | 29.6817 |
| 2010's | 15 (15.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pomozi, V | 2 |
| Brampton, C | 1 |
| van de Wetering, K | 1 |
| Zoll, J | 1 |
| Calio, B | 1 |
| Pham, K | 1 |
| Owens, JB | 1 |
| Marh, J | 1 |
| Moisyadi, S | 1 |
| Váradi, A | 1 |
| Martin, L | 1 |
| Bauer, C | 2 |
| Erdmann, J | 2 |
| Aherrahrou, Z | 2 |
| Le Saux, O | 2 |
| Aherrahrou, R | 1 |
| Kriesen, R | 1 |
| Stölting, S | 1 |
| Liebers, A | 1 |
| Kessler, T | 1 |
| Schunkert, H | 1 |
| Kawahara, T | 2 |
| Nishikawa, M | 1 |
| Kawahara, C | 1 |
| Inazu, T | 1 |
| Sakai, K | 1 |
| Suzuki, G | 1 |
| King, A | 1 |
| de Graaf, P | 1 |
| Schicht, IM | 1 |
| Pauwels, EK | 3 |
| Souverijn, JH | 1 |
| de Graeff, J | 1 |
| Apschner, A | 1 |
| Huitema, LF | 1 |
| Ponsioen, B | 1 |
| Peterson-Maduro, J | 1 |
| Schulte-Merker, S | 1 |
| Rathan, S | 1 |
| Yoganathan, AP | 1 |
| O'Neill, CW | 1 |
| Cakir, E | 1 |
| Gedik, AH | 1 |
| Özdemir, A | 1 |
| Buyukpınarbasili, N | 1 |
| Bilgin, M | 1 |
| Ozgen, IT | 1 |
| Zhao, L | 1 |
| Huang, L | 1 |
| Zhang, X | 1 |
| Saito, A | 1 |
| McCormack, FX | 1 |
| Emiralioglu, N | 1 |
| Beken, B | 1 |
| Ozcan, HN | 1 |
| Yalcin, E | 1 |
| Dogru, D | 1 |
| Ozcelik, U | 1 |
| Haliloglu, M | 1 |
| Kiper, N | 2 |
| Lomashvili, KA | 1 |
| Monier-Faugere, MC | 1 |
| Wang, X | 1 |
| Malluche, HH | 1 |
| O'Neill, WC | 1 |
| Neven, EG | 1 |
| De Broe, ME | 1 |
| D'Haese, PC | 1 |
| Obad, D | 1 |
| Larsen, NA | 1 |
| Pedersen, EB | 1 |
| Kanazawa, I | 1 |
| Yamaguchi, T | 1 |
| Hayashi, K | 1 |
| Takase, H | 1 |
| Shimizu, T | 1 |
| Sugimoto, T | 1 |
| Okada, Y | 4 |
| Mori, H | 3 |
| Tanaka, Y | 4 |
| Hashimoto, O | 1 |
| Mackenzie, NC | 1 |
| Zhu, D | 1 |
| Longley, L | 1 |
| Patterson, CS | 1 |
| Kommareddy, S | 1 |
| MacRae, VE | 1 |
| Yamaoka, K | 1 |
| Saito, K | 2 |
| Ito, G | 1 |
| Suzuki, Y | 3 |
| Uehara, R | 1 |
| Ide, M | 1 |
| Ozaki, S | 1 |
| Grases, F | 2 |
| Perelló, J | 2 |
| Prieto, RM | 2 |
| Simonet, BM | 1 |
| Torres, JJ | 2 |
| Hashiba, H | 3 |
| Aizawa, S | 4 |
| Tamura, K | 4 |
| Shigematsu, T | 2 |
| Kogo, H | 4 |
| Tamura, H | 1 |
| Honjo, S | 1 |
| Yokote, K | 1 |
| Takada, A | 1 |
| Maezawa, Y | 1 |
| Kobayashi, K | 1 |
| Tokuyama, T | 1 |
| Sonezaki, K | 1 |
| Saito, Y | 1 |
| Neau-Cransac, M | 1 |
| Lepreux, S | 1 |
| Labreze, C | 1 |
| Quinart, A | 1 |
| Revel, P | 1 |
| Saric, J | 1 |
| Bioulac-Sage, P | 1 |
| Loeb, JA | 2 |
| Sohrab, SA | 1 |
| Huq, M | 1 |
| Fuerst, DR | 1 |
| Trullemans, B | 1 |
| Bottu, J | 1 |
| Van Nieuwenhuyse, JP | 1 |
| Ariyoshi, T | 1 |
| Eishi, K | 1 |
| Sakamoto, I | 1 |
| Matsukuma, S | 1 |
| Odate, T | 1 |
| Matsushita, M | 1 |
| Fujii, H | 1 |
| Miyaura, C | 1 |
| Kishikawa, H | 1 |
| Sanchis, P | 1 |
| Isern, B | 1 |
| Fernández-Palomeque, C | 1 |
| McClure, J | 5 |
| Miller, S | 1 |
| Vernon-Roberts, E | 1 |
| Martin-Simmerman, P | 1 |
| Cohen, MD | 1 |
| Siddiqui, A | 1 |
| Mirkin, D | 1 |
| Provisor, A | 1 |
| Fleisch, H | 3 |
| Dirksen, G | 1 |
| Sachs, M | 1 |
| Held, T | 1 |
| Nowotzin, C | 1 |
| Hänichen, T | 1 |
| Meyer, J | 1 |
| Rambeck, WA | 1 |
| Zucker, H | 1 |
| Leicht, E | 1 |
| Tkocz, HJ | 1 |
| Seeliger, H | 1 |
| Lauffenburger, T | 1 |
| Haas, HG | 1 |
| Klemm, G | 1 |
| Putzke, HP | 1 |
| Ibels, LS | 2 |
| Alfrey, AC | 1 |
| Caughey, JE | 1 |
| Gray, P | 1 |
| Weinstein, RS | 1 |
| Hirsch, D | 2 |
| Drader, J | 1 |
| Pathak, YV | 1 |
| Yee, R | 1 |
| Schoen, FJ | 9 |
| Levy, RJ | 10 |
| Kawaguchi, Y | 1 |
| Hasegawa, T | 1 |
| Kubo, H | 1 |
| Yamamoto, H | 1 |
| Nakayama, M | 1 |
| Van Gelder, JM | 1 |
| Breuer, E | 1 |
| Schlossman, A | 1 |
| Ornoy, A | 1 |
| Mönkkönen, J | 1 |
| Similä, J | 1 |
| Klenner, T | 1 |
| Stadler, H | 1 |
| Krempien, B | 1 |
| Patlas, N | 1 |
| Golomb, G | 4 |
| Jono, S | 2 |
| Nishizawa, Y | 2 |
| Shioi, A | 2 |
| Morii, H | 2 |
| Mori, K | 1 |
| Naito, T | 1 |
| Nitta, K | 1 |
| Kimata, N | 1 |
| Honda, K | 1 |
| Yoshida, T | 1 |
| Koinuma, M | 1 |
| Ikeda, Y | 1 |
| Kato, Y | 1 |
| Nihei, H | 1 |
| Goldstein, MR | 1 |
| Price, PA | 1 |
| Faus, SA | 1 |
| Williamson, MK | 1 |
| Schneider, VS | 1 |
| LeBlanc, A | 1 |
| Huntoon, CL | 1 |
| Zucchelli, P | 1 |
| Fusaroli, M | 1 |
| Fabbri, L | 1 |
| Pavlica, P | 1 |
| Casanova, S | 1 |
| Viglietta, G | 1 |
| Sasdelli, M | 1 |
| Schäfer, HJ | 1 |
| Riesner, K | 1 |
| Schlangen, JT | 1 |
| Doyle, DV | 1 |
| Dunn, CJ | 1 |
| Willoughby, DA | 1 |
| Reimann, E | 1 |
| Münzenberg, KJ | 1 |
| Gebhardt, M | 1 |
| Russell, RG | 2 |
| Uttley, WS | 2 |
| Belton, NR | 1 |
| Syme, J | 2 |
| Sheppard, H | 2 |
| O'Hara, JP | 1 |
| Jowsey, J | 1 |
| Williams, GA | 1 |
| Newsome, AL | 1 |
| Harley, JP | 1 |
| Saunders, RL | 1 |
| Kramsch, DM | 1 |
| Chan, CT | 1 |
| Meradji, M | 1 |
| de Villeneuve, VH | 1 |
| Huber, J | 1 |
| de Bruijn, WC | 1 |
| Pearse, RG | 1 |
| Rabens, SF | 1 |
| Bethune, JE | 1 |
| Smith, R | 1 |
| Woods, CG | 1 |
| Goel, KM | 1 |
| Shanks, RA | 1 |
| Allen, SH | 1 |
| Shah, JH | 1 |
| Bellah, RD | 1 |
| Zawodniak, L | 1 |
| Librizzi, RJ | 1 |
| Harris, MC | 1 |
| Göcmen, A | 1 |
| Toppare, MF | 1 |
| Büyükpamukcu, N | 1 |
| de Jonge, FA | 1 |
| Hamdy, NA | 1 |
| Kingma, JG | 1 |
| Roy, PE | 1 |
| Stuart, G | 1 |
| Wren, C | 1 |
| Bain, H | 1 |
| Morris, DC | 1 |
| Anderson, HC | 1 |
| Yoshikawa, H | 1 |
| Nakahara, H | 1 |
| Takaoka, K | 1 |
| Ono, K | 1 |
| Dewanjee, MK | 1 |
| Solis, E | 1 |
| Mackey, ST | 1 |
| Lenker, J | 1 |
| Edwards, WD | 1 |
| Didisheim, P | 1 |
| Chesebro, JH | 1 |
| Zollman, PE | 1 |
| Kaye, MP | 1 |
| Dixon, M | 1 |
| Smith, MS | 2 |
| Lund, SA | 4 |
| Schneider, HG | 1 |
| Minne, HW | 1 |
| Raue, F | 1 |
| Fichtner, HJ | 1 |
| Baldauf, G | 1 |
| Ziegler, R | 1 |
| Webb, CL | 1 |
| Benedict, JJ | 1 |
| Linden, JA | 1 |
| Johnston, TP | 1 |
| Barbarash, LS | 1 |
| Zhuravleva, IIu | 1 |
| Medvedeva, VM | 1 |
| Shaposhnikov, AN | 1 |
| Hawley, MA | 2 |
| Liu, PY | 1 |
| Wolfrum, J | 2 |
| Langer, R | 2 |
| Spiro, J | 1 |
| Gordon, B | 1 |
| Raper, RF | 1 |
| Metzger, AL | 1 |
| Singer, FR | 1 |
| Bluestone, R | 1 |
| Pearson, CM | 1 |
| Belton, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intestinal Microbiota and Vitamin K Levels in PXE Patients (IMPROVE Study)[NCT03813550] | 20 participants (Anticipated) | Interventional | 2019-01-21 | Recruiting | |||
| Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications[NCT01000233] | Phase 2/Phase 3 | 250 participants (Anticipated) | Interventional | 2009-08-31 | Recruiting | ||
| Effect of Vitamin K2 Supplementation on Vascular Calcification in Hemodialysis Patients: a Controlled Randomized Trial.[NCT04539418] | Phase 4 | 59 participants (Actual) | Interventional | 2016-12-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for etidronate and Calcification, Pathologic
| Article | Year |
|---|---|
Systemic lupus erythematosus-related hypercalcemia with ectopic calcinosis.
Topics: Adult; Biomarkers; Bone Density Conservation Agents; Calcinosis; Calcitonin; Cyclophosphamide; Drug | 2016 |
Pulmonary Alveolar Microlithiasis.
Topics: Bone Density Conservation Agents; Calcinosis; Calcium Phosphates; Etidronic Acid; Genetic Diseases, | 2016 |
[Positioning of bisphosphonates for vascular calcification].
Topics: Animals; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Calcinosis; Clinical Trial | 2010 |
Diphosphonates: history and mechanisms of action.
Topics: Animals; Bone Resorption; Calcification, Physiologic; Calcinosis; Calcium Phosphates; Clodronic Acid | 1981 |
Current issues of continuous ambulatory peritoneal dialysis.
Topics: Adult; Calcinosis; Cohort Studies; Etidronic Acid; Female; Humans; Japan; Male; Middle Aged; Nutriti | 1995 |
Pyrophosphate and diphosphonates in skeletal metabolism. Physiological, clinical and therapeutic aspects.
Topics: Animals; Bone and Bones; Bone Resorption; Calcification, Physiologic; Calcinosis; Calcium; Calcium M | 1975 |
Calcinosis and metastatic calcification due to vitamin D intoxication. A case report and review.
Topics: Adult; Aluminum Hydroxide; Calcinosis; Ergocalciferols; Etidronic Acid; Humans; Joint Diseases; Male | 1992 |
Scintigraphy in the clinical evaluation of disorders of mineral and skeletal metabolism in renal failure.
Topics: Amyloidosis; Calcinosis; Chronic Kidney Disease-Mineral and Bone Disorder; Etidronic Acid; Humans; K | 1991 |
[Pathogenesis and prevention of calcinosis of bioprostheses].
Topics: Animals; Bioprosthesis; Calcinosis; Disease Models, Animal; Etidronic Acid; Heart Valve Prosthesis; | 1991 |
[Biphosphonate as a therapeutic drug--experimental studies and clinical application].
Topics: Animals; Calcinosis; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hypercalcemia; Hyperpar | 1985 |
5 trials available for etidronate and Calcification, Pathologic
| Article | Year |
|---|---|
Atorvastatin, etidronate, or both in patients at high risk for atherosclerotic aortic plaques: a randomized, controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Aorta, Abdominal; Aorta, Thoracic; Aortic Diseases; Atorvastatin; Bo | 2013 |
Inhibitory effects of etidronate on the progression of vascular calcification in hemodialysis patients.
Topics: Aged; Aorta; Bone Density; Calcinosis; Calcium; Etidronic Acid; Female; Humans; Male; Middle Aged; P | 2004 |
Brain calcifications induce neurological dysfunction that can be reversed by a bone drug.
Topics: Bone Density Conservation Agents; Brain; Brain Damage, Chronic; Brain Diseases; Calcinosis; Calcium | 2006 |
Inhibition of the progression of aortic calcification by etidronate treatment in hemodialysis patients: long-term effects.
Topics: Aortic Diseases; Bone Density; Bone Density Conservation Agents; Calcinosis; Disease Progression; Et | 2006 |
Effect of etidronic acid on arterial calcification in dialysis patients.
Topics: Aged; Aorta, Abdominal; Aorta, Thoracic; Bone Density Conservation Agents; Calcinosis; Coronary Vess | 2006 |
80 other studies available for etidronate and Calcification, Pathologic
| Article | Year |
|---|---|
Pyrophosphate Supplementation Prevents Chronic and Acute Calcification in ABCC6-Deficient Mice.
Topics: Acute Disease; Animals; ATP-Binding Cassette Transporters; Calcinosis; Chronic Disease; Diphosphates | 2017 |
Etidronate prevents dystrophic cardiac calcification by inhibiting macrophage aggregation.
Topics: Animals; Bone Density Conservation Agents; Calcinosis; Cardiovascular Diseases; Cell Aggregation; Ce | 2018 |
Vascular disease: aortic plaque--dual therapy for a heterogeneous disease.
Topics: Aortic Diseases; Calcinosis; Etidronic Acid; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl- | 2013 |
Bone scintigraphy in uremic pulmonary calcification.
Topics: Adolescent; Adult; Bone and Bones; Calcinosis; Etidronic Acid; Female; Humans; Kidney Failure, Chron | 1979 |
Zebrafish enpp1 mutants exhibit pathological mineralization, mimicking features of generalized arterial calcification of infancy (GACI) and pseudoxanthoma elasticum (PXE).
Topics: Animals; Biomarkers; Calcinosis; Calcium; Choristoma; Etidronic Acid; Fibroblast Growth Factor-23; H | 2014 |
The role of inorganic pyrophosphate in aortic valve calcification.
Topics: Alkaline Phosphatase; Animals; Aortic Valve; Aortic Valve Stenosis; Calcinosis; Diphosphates; Etidro | 2014 |
Response to Disodium Etidronate Treatment in Three Siblings with Pulmonary Alveolar Microlithiasis.
Topics: Bone Density Conservation Agents; Calcinosis; Child; Child, Preschool; Etidronic Acid; Female; Genet | 2015 |
Diagnosis and treatment of pulmonary alveolar microlithiasis.
Topics: Adolescent; Biopsy; Bone Density Conservation Agents; Calcinosis; Child; Etidronic Acid; Genetic Dis | 2016 |
Effect of bisphosphonates on vascular calcification and bone metabolism in experimental renal failure.
Topics: Animals; Aortic Diseases; Bone and Bones; Bone Resorption; Calcification, Physiologic; Calcinosis; D | 2009 |
Prevention of vascular calcification with bisphosphonates without affecting bone mineralization: a new challenge?
Topics: Animals; Aortic Diseases; Calcification, Physiologic; Calcinosis; Diphosphonates; Etidronic Acid; Hu | 2009 |
[Regression of severe periarticular calcifications during treatment with bisphosphonate in a dialysis patient].
Topics: Bone Density Conservation Agents; Calcinosis; Etidronic Acid; Humans; Kidney Failure, Chronic; Male; | 2010 |
Effects of treatment with risedronate and alfacalcidol on progression of atherosclerosis in postmenopausal women with type 2 diabetes mellitus accompanied with osteoporosis.
Topics: Aged; Aorta, Abdominal; Atherosclerosis; Body Mass Index; Bone Density Conservation Agents; Calcinos | 2010 |
MOVAS-1 cell line: a new in vitro model of vascular calcification.
Topics: Alkaline Phosphatase; Animals; Anthraquinones; Bone Density Conservation Agents; Calcinosis; Calcium | 2011 |
Marked improvement of calcinosis in adult dermatomyositis with etidronate therapy.
Topics: Adult; Alkaline Phosphatase; Bone Density; Calcinosis; Collagen Type I; Dermatomyositis; Etidronic A | 2012 |
[Beneficial effect of high-dose etidronate on periarticular calcinosis associated with arterial and periarticular basic calcium phosphate (BCP) crystal deposition disease].
Topics: Calcinosis; Calcium Phosphates; Crystallization; Etidronic Acid; Female; Humans; Joint Diseases; Mid | 2003 |
Dietary myo-inositol hexaphosphate prevents dystrophic calcifications in soft tissues: a pilot study in Wistar rats.
Topics: Administration, Oral; Animals; Calcinosis; Diet; Disease Models, Animal; Etidronic Acid; Injections, | 2004 |
Effect of etidronate on aortic calcification and bone metabolism in calcitriol-treated rats with subtotal nephrectomy.
Topics: Amino Acids; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Diseases; Body Weight; Bone and Bone | 2005 |
Etidronate ameliorates painful soft-tissue calcification in Werner syndrome.
Topics: Adenosine Triphosphatases; Calcinosis; Connective Tissue; DNA Helicases; DNA Mutational Analysis; Et | 2005 |
Uncommon localization of calcinosis cutis after liver transplantation.
Topics: Adult; Bone Density Conservation Agents; Calcinosis; Etidronic Acid; Graft Rejection; Humans; Hyperc | 2005 |
[Etidronate per os in subcutaneous fat necrosis with hypercalcemia and nephrocalcinosis].
Topics: Adipose Tissue; Calcinosis; Etidronic Acid; Female; Humans; Hypercalcemia; Infant; Kidney Diseases; | 2007 |
Prevention of aortic calcification by etidronate in the renal failure rat model.
Topics: Animals; Aortic Diseases; Bone Density; Calcinosis; Calcium; Calcium-Binding Proteins; Disease Model | 2007 |
A case of blue rubber bleb nevus syndrome treated by etidronate.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Bone Density Conservation Agents; Calcinosis; Colono | 2007 |
Effect of crystallization inhibitors on vascular calcifications induced by vitamin D: a pilot study in Sprague-Dawley rats.
Topics: Animals; Aorta; Atherosclerosis; Bone Density Conservation Agents; Calcinosis; Calcium; Crystallizat | 2007 |
Etidronate for the treatment of progressive tumoral calcinosis in hemodialysis patients.
Topics: Adult; Bone Density Conservation Agents; Calcinosis; Disease Progression; Etidronic Acid; Humans; Ki | 2007 |
Skeletal muscle calcergy.
Topics: Animals; Calcinosis; Clodronic Acid; Etidronic Acid; Hexadimethrine Bromide; Male; Mice; Muscles; Mu | 1982 |
The effects of disodium ethane-hydroxy-1,1-diphosphonate and disodium dichloromethylene diphosphonate on lanthanide-induced calcergy.
Topics: Animals; Calcinosis; Clodronic Acid; Diphosphonates; Disease Models, Animal; Etidronic Acid; Hydroca | 1982 |
The effects of various anti-calcific, anti-rheumatic and anti-inflammatory drugs on local (simple) calcergy induced by lead acetate in the mouse.
Topics: Animals; Calcinosis; Clodronic Acid; Connective Tissue; Connective Tissue Diseases; Diphosphonates; | 1982 |
Cutaneous calciphylactic reactions in the mouse and the rat and the effects of diphosphonates on the reaction in the rat.
Topics: Animals; Calcinosis; Calciphylaxis; Chlorides; Clodronic Acid; Dihydrotachysterol; Diphosphonates; D | 1984 |
Calcification and uptake of Tc-99m diphosphonates in neuroblastomas: concise communication.
Topics: Abdominal Neoplasms; Bone and Bones; Calcinosis; Diphosphonates; Etidronic Acid; Female; Homovanilli | 1984 |
[Effect of aluminum hydroxide and l-hydroxyethane-1,1-diphosphonate (EHDP) on the calcinogenic effect of Trisetum flavescens (L.,P.B.) in sheep].
Topics: Aluminum Hydroxide; Animals; Calcinosis; Etidronic Acid; Female; Male; Plant Poisoning; Plants, Toxi | 1983 |
Tumoral calcinosis. Observations during six years.
Topics: Amyloidosis; Biopsy; Calcinosis; Etidronic Acid; Female; Humans; Hypercalcemia; Lipoproteins, VLDL; | 1980 |
[Inhibitory action of diphosphonate on the development of pancreatic concrements (experiment with EHDP (author's transl)].
Topics: Animals; Calcinosis; Calculi; Etidronic Acid; Female; Iron-Dextran Complex; Pancreas; Pancreatic Dis | 1981 |
Effects of thyroparathyroidectomy, phosphate depletion and diphosphonate therapy on acute uraemic extra-osseous calcification in the rat.
Topics: Animals; Calcinosis; Calcium; Etidronic Acid; Male; Parathyroid Glands; Phosphates; Rats; Rats, Inbr | 1981 |
Heterotopic calcification complicating infectious polyneuritis.
Topics: Adult; Alkaline Phosphatase; Calcinosis; Etidronic Acid; Hip; Humans; Male; Paraplegia; Polyneuropat | 1982 |
Focal mineralization defect during disodium etidronate treatment of calcinosis.
Topics: Bone Diseases; Calcinosis; Child; Dermatomyositis; Etidronic Acid; Female; Humans | 1982 |
Synergistic inhibition of the calcification of glutaraldehyde pretreated bovine pericardium in a rat subdermal model by FeCl3 and ethanehydroxydiphosphonate: preincubation and polymeric controlled release studies.
Topics: Animals; Bioprosthesis; Calcinosis; Cattle; Chlorides; Delayed-Action Preparations; Disease Models, | 1993 |
Effects of metallic ions and diphosphonates on inhibition of pericardial bioprosthetic tissue calcification and associated alkaline phosphatase activity.
Topics: Alkaline Phosphatase; Animals; Bioprosthesis; Calcinosis; Cattle; Diphosphonates; Etidronic Acid; Gl | 1993 |
In vitro and in vivo effects of tetrakisphosphonates on bone resorption, tumor osteolysis, ectopic calcification, and macrophages.
Topics: Animals; Bioprosthesis; Bone Resorption; Calcinosis; Carcinoma 256, Walker; Cell Line; Cell Survival | 1997 |
Parathyroid hormone-related peptide as a local regulator of vascular calcification. Its inhibitory action on in vitro calcification by bovine vascular smooth muscle cells.
Topics: Alkaline Phosphatase; Animals; Calcinosis; Calcium; Cattle; Cells, Cultured; Cyclic AMP-Dependent Pr | 1997 |
Functional improvement in a patient with cerebral calcinosis using a bisphosphonate.
Topics: Basal Ganglia Diseases; Brain Mapping; Calcinosis; Etidronic Acid; Gait; Humans; Male; Middle Aged; | 1998 |
Expression of matrix Gla protein (MGP) in an in vitro model of vascular calcification.
Topics: Alendronate; Animals; Blotting, Northern; Calcinosis; Calcium; Calcium-Binding Proteins; Cattle; Cel | 1998 |
Progressive tumoral calcinosis as the presenting feature of sarcoidosis in a patient on haemodialysis treatment.
Topics: Adult; Calcinosis; Calcitonin; Drug Therapy, Combination; Etidronic Acid; Glucocorticoids; Humans; L | 1999 |
Bisphosphonate therapy and vascular calcification.
Topics: Blood Vessels; Calcification, Physiologic; Calcinosis; Calcium Channel Blockers; Cardiovascular Dise | 2000 |
Bisphosphonates alendronate and ibandronate inhibit artery calcification at doses comparable to those that inhibit bone resorption.
Topics: Alendronate; Animals; Aortic Diseases; Bone Resorption; Calcification, Physiologic; Calcinosis; Diph | 2001 |
Prevention of space flight induced soft tissue calcification and disuse osteoporosis.
Topics: Bed Rest; Bone and Bones; Bone Demineralization, Pathologic; Calcinosis; Calcium; Clodronic Acid; Et | 1993 |
Treatment of ectopic calcification in uremia.
Topics: Adult; Biopsy; Calcinosis; Etidronic Acid; Female; Humans; Ilium; Male; Middle Aged; Remission, Spon | 1978 |
[Calcium kinetics of myocardium in experimental hypercalcemia and isoproterenol lesions--ultrastructural and roentgen microanalytical findings].
Topics: Animals; Calcinosis; Calcium; Dihydrotachysterol; Etidronic Acid; Heart; Hypercalcemia; Isoprotereno | 1978 |
[The diagnosis of pulmonary calcinosis by scintigraphy (author's transl)].
Topics: Adolescent; Adult; Aged; Calcinosis; Diagnosis, Differential; Etidronic Acid; Female; Glomerulonephr | 1976 |
Potassium permanganate induced calcergy: a model to study the effects of drugs on hydroxyapatite crystal deposition.
Topics: Animals; Calcinosis; Clodronic Acid; Dexamethasone; Disease Models, Animal; Etidronic Acid; Hydroxya | 1979 |
[On the effect of methane-bis--phosphonate in vivo (author's transl)].
Topics: Animals; Apatites; Calcinosis; Clodronic Acid; Diphosphonates; Etidronic Acid; Injections, Subcutane | 1978 |
Calcium balance in children treated with diphosphonates.
Topics: Adenosine Monophosphate; Adrenocorticotropic Hormone; Bone and Bones; Calcinosis; Calcium; Child; Ch | 1975 |
Effects of dichloromethylene diphosphonate, ethane-1-hydroxy-1,1-diphosphonate, and rickets in rats.
Topics: Acetates; Animals; Bone and Bones; Bone Development; Bone Resorption; Calcinosis; Calcium; Diet; Eti | 1975 |
Trichinella spiralis: acceleration and inhibition of cyst calcification in rats.
Topics: Animals; Calcinosis; Cholecalciferol; Etidronic Acid; Larva; Male; Rats; Trichinella; Trichinellosis | 1978 |
A comparison of the inhibitory effects of disodium pyrophosphate and disodium ethane-hydroxy-1, 1-diphosphonate on simple calcergy.
Topics: Animals; Calcinosis; Diphosphates; Etidronic Acid; Lead; Male; Mice; Skin; Time Factors | 1979 |
Appearance of a gastric ulcer during diphosphonate therapy in a woman with CRST syndrome.
Topics: Calcinosis; Etidronic Acid; Female; Humans; Middle Aged; Radiography; Raynaud Disease; Scleroderma, | 1977 |
The effect of agents interfering with soft tissue calcification and cell proliferation on calcific fibrous-fatty plaques in rabbits.
Topics: Animals; Aorta; Arteriosclerosis; Calcinosis; Cholesterol; Demecolcine; Diet, Atherogenic; Elastin; | 1978 |
Idiopathic infantile arterial calcification in siblings: radiologic diagnosis and successful treatment.
Topics: Arteriosclerosis; Calcinosis; Coronary Disease; Etidronic Acid; Female; Humans; Infant, Newborn; Inf | 1978 |
Disodium etidronate therapy for dystrophic cutaneous calcification.
Topics: Abscess; Administration, Oral; Calcinosis; Elbow; Etidronic Acid; Female; Humans; Knee; Middle Aged; | 1975 |
Myositis ossificans progressiva. Clinical features of eight patients and their response to treatment.
Topics: Adolescent; Adult; Calcinosis; Child; Etidronic Acid; Female; Humans; Male; Myositis Ossificans; Org | 1976 |
Dermatomyositis in childhood. Review of eight cases.
Topics: Biopsy; Calcinosis; Child; Child, Preschool; Dermatomyositis; Etidronic Acid; Female; Follow-Up Stud | 1976 |
Idiopathic arterial calcification of infancy: prenatal and postnatal effects of therapy in an infant.
Topics: Arterial Occlusive Diseases; Calcinosis; Etidronic Acid; Female; Heart Failure; Humans; Infant; Nitr | 1992 |
Treatment of pulmonary alveolar microlithiasis with a diphosphonate--preliminary results of a case.
Topics: Calcinosis; Calculi; Child, Preschool; Etidronic Acid; Female; Humans; Lung Diseases; Pulmonary Alve | 1992 |
Effect of ethane-I-hydroxy-I, I-diphosphonate on arterial calcinosis induced by hypervitaminosis D: a morphologic investigation.
Topics: Animals; Aorta, Thoracic; Aortic Diseases; Calcinosis; Ergocalciferols; Etidronic Acid; Male; Micros | 1990 |
Idiopathic infantile arterial calcification in two siblings: failure of treatment with diphosphonate.
Topics: Calcinosis; Consanguinity; Echocardiography; Etidronic Acid; Female; Fetal Diseases; Humans; Infant, | 1990 |
Matrix vesicle calcification of ectopically induced osteoid tissue in 1-hydroxethylidene-1,1-bisphosphonate (HEBP)-treated mice.
Topics: Animals; Bone Morphogenetic Proteins; Calcinosis; Etidronic Acid; Extracellular Matrix; Injections, | 1990 |
Quantification of regional platelet and calcium deposition on pericardial tissue valve prostheses in calves and effect of hydroxyethylene diphosphonate.
Topics: Animals; Calcinosis; Calcium; Calcium Phosphates; Cattle; Cell Survival; Etidronic Acid; Heart Valve | 1986 |
Controlled-release drug delivery of diphosphonates to inhibit bioprosthetic heart valve calcification: release rate modulation with silicone matrices via drug solubility and membrane coating.
Topics: Animals; Bioprosthesis; Calcinosis; Delayed-Action Preparations; Etidronic Acid; Heart Valve Prosthe | 1987 |
Prevention of leaflet calcification of bioprosthetic heart valves with diphosphonate injection therapy. Experimental studies of optimal dosages and therapeutic durations.
Topics: Animals; Bioprosthesis; Calcinosis; Diphosphonates; Dose-Response Relationship, Drug; Drug Evaluatio | 1987 |
[Extraosseous calcification in juvenile dermatomyositis. The ineffectiveness of EHDP].
Topics: Adult; Calcinosis; Chronic Disease; Dermatomyositis; Drug Evaluation; Drug Therapy, Combination; Eti | 1988 |
Inhibition of bioprosthetic heart valve calcification with aminodiphosphonate covalently bound to residual aldehyde groups.
Topics: Aldehydes; Animals; Aortic Valve Stenosis; Bioprosthesis; Calcinosis; Cattle; Diphosphonates; Diseas | 1988 |
Controlled release of diphosphonates from synthetic polymers to inhibit calcification.
Topics: Animals; Bioprosthesis; Calcinosis; Diphosphonates; Etidronic Acid; Heart Valve Prosthesis; Male; Ma | 1987 |
Prevention of calcification of bioprosthetic heart valve leaflets by Ca2+ diphosphonate pretreatment.
Topics: Animals; Bone and Bones; Calcinosis; Cattle; Diphosphonates; Drug Implants; Etidronic Acid; Heart Va | 1988 |
[Ways to prevent the calcification of heart valve bioprostheses].
Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Diphosphonates; Drug Evaluation, Preclinical; Etid | 1988 |
Inhibition by diphosphonate compounds of calcification of porcine bioprosthetic heart valve cusps implanted subcutaneously in rats.
Topics: Animals; Bioprosthesis; Calcinosis; Diphosphonates; Etidronic Acid; Femur; Heart Valve Prosthesis; H | 1985 |
Inhibition of calcification of bioprosthetic heart valves by local controlled-release diphosphonate.
Topics: Animals; Bioprosthesis; Bone Development; Calcinosis; Delayed-Action Preparations; Etidronic Acid; H | 1985 |
Calcinosis universalis treated with disodium etidronate.
Topics: Calcinosis; Child; Etidronic Acid; Female; Humans | 1985 |
Osteosclerotic myeloma complicated by diffuse arteritis, vascular calcification and extensive cutaneous necrosis.
Topics: Adult; Aluminum Hydroxide; Arteritis; Bone Neoplasms; Calcinosis; Cyclophosphamide; Etidronic Acid; | 1985 |
Local controlled-release of diphosphonates from ethylenevinylacetate matrices prevents bioprosthetic heart valve calcification.
Topics: Animals; Bone Development; Calcinosis; Calcium; Delayed-Action Preparations; Etidronic Acid; Heart V | 1985 |
Failure of disodium etidronate in calcinosis due to dermatomyositis and scleroderma.
Topics: Administration, Oral; Calcinosis; Dermatomyositis; Etidronic Acid; Female; Humans; Male; Organophosp | 1974 |
Proceedings: Use of diphosphonates in diseases associated with ectopic calcification.
Topics: Apatites; Calcinosis; Calcium; Etidronic Acid; Humans; Organophosphorus Compounds; Ossification, Het | 1974 |